Zobrazeno 1 - 10 of 20 pro vyhledávání: '"E. R. BACON"'
1
Hemoglobin Switching in Humans Is Accompanied by Changes in the Ratio of the Transcription Factors, GATA-1 and SP1
Autor: Ariella Oppenheim, L Schreiber, E R Bacon, Eliezer A. Rachmilewitz, Nava Dalyot, Dvora Filon
Publikováno v: Molecular Medicine. 1:297-305
Understanding the mechanism of developmental regulation of hemoglobin switching has scientific as well as clinical relevance because of the influence of fetal hemoglobin (HbF) production in adulthood on the clinical manifestation of thalassemia and s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e329fe7574d0d65c7274604420774b58
https://doi.org/10.1007/bf03401554
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2
A short and general synthesis of 1,3-dihydro-6-heteroaryl-5-perfluoroalkyl-2H-imidazo[4,5-b]pyridin-2-ones
Autor: George Y. Lesher, Baldev Singh, E. R. Bacon, Michael Eissenstat, Gee-Hong Kuo
Publikováno v: Journal of Heterocyclic Chemistry. 30:37-40
Trifluoro or pentafluoroacylation of heteroaryl-enamines 2a,b gave the corresponding perfluoroacylated heteroaryl-enamines 3a-c. Heating the latter compounds with diethyl iminomalonate gave 2-amino-3-pyridinecarboxylates 4a-c. Hydrolysis to the free
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b75f28377b83316bf9b05a44d00676fd
https://doi.org/10.1002/jhet.5570300107
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4
ChemInform Abstract: A Short and General Synthesis of 1,3-Dihydro-6-heteroaryl-5- perfluoroalkyl-2H-imidazo(4,5-b)pyridin-2-ones
Autor: E. R. Bacon, George Y. Lesher, Baldev Singh, Michael Eissenstat, Gee-Hong Kuo
Publikováno v: ChemInform. 24
Trifluoro or pentafluoroacylation of heteroaryl-enamines 2a,b gave the corresponding perfluoroacylated heteroaryl-enamines 3a-c. Heating the latter compounds with diethyl iminomalonate gave 2-amino-3-pyridinecarboxylates 4a-c. Hydrolysis to the free
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e56b86801b9affd223b8c72fcdb39bb9
https://doi.org/10.1002/chin.199333179
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8
Pharmacokinetics and hepatic disposition of bis[1-(ethoxycarbonyl)propyl]5-acetylamino-2,4,6-triiodoisophthalate in rats and isolated perfused rat livers
Autor: Y, Liu, E R, Bacon, K, Ballinger, C D, Black, K, Illig, G L, McIntire, P P, Wang, N, O'Neil, L, Kinter, V C, Desai
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 28(7)
Bis[1-(Ethoxycarbonyl)propyl]5-acetylamino-2,4,6- triiodoisophthalate+ (NC 68183) was designed as a new computed tomography imaging agent. The purpose of this study was to determine the pharmacokinetics and metabolism of NC 68183 in conscious rats an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24a79b91312cabd0fb7def87c6d0b6a0
https://pubmed.ncbi.nlm.nih.gov/10859144
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9
Synthesis of 7-ethyl-4,7-dihydro-4-oxo-2-(4-pyridinyl)thieno[2,3-b]pyridine-5-carboxylic acid
Autor: Sol J. Daum, E. R. Bacon
Publikováno v: Journal of Heterocyclic Chemistry. 28:1953-1955
7-Ethyl-4,7-dihydro-4-oxo-2-(4-pyridinyl)thieno[2,3-b]pyridine-5-carboxylic acid (4), an analog of nalidixic acid, was synthesized in seven steps starting from commercially available 4-methylpyridine. Bacterial susceptibility to compound 4 was tested
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5fa18ff96609167fa6315fdd813bf384
https://doi.org/10.1002/jhet.5570280826
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10
Antiviral properties of 3-quinolinecarboxamides: a series of novel non-nucleoside antiherpetic agents
Autor: M P, Wentland, R B, Perni, P H, Dorff, R P, Brundage, M J, Castaldi, J A, Carlson, T R, Bailey, S C, Aldous, P M, Carabateas, E R, Bacon, R K, Kullnig, D C, Young, M G, Woods, S D, Kingsley, K A, Ryan, D, Rosi, M L, Drozd, F J, Dutko
Publikováno v: Drug design and discovery. 15(1)
Novel antiherpetic 3-quinolinecarboxamides were discovered as part of a drug discovery program at Sterling Winthrop Inc. A major goal of this research was to identify novel non-nucleoside agents possessing activity against acyclovir resistant herpes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b901a023688a7a67d516ed7f0308037
https://pubmed.ncbi.nlm.nih.gov/9332829
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