Exploring the predictive potential of programmed death ligand 1 expression in healthy organs and lymph nodes as measured by 18F-BMS-986192 PET: pooled analysis of data from four solid tumor types

Autor: Tanja D de Gruijl, Rieneke van de Ven, Geke A P Hospers, Marc C Huisman, Gerben J C Zwezerijnen, C Willemien Menke-van der Houven van Oordt, Iris H C Miedema, Johanna E. E. Pouw, Anne Kwakman, Florentine E F Timmer, Adrianus J de Langen

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)

Introduction Immune checkpoint inhibitors (ICIs) can elicit anticancer immune responses, but predictive biomarkers are needed. We measured programmed death ligand 1 (PD-L1) expression in organs and lymph nodes using 18F-BMS-986192 positron emission t

Externí odkaz: https://doaj.org/article/25fc274b5a5a47a2b15beea98d6e7ced

First exploration of the on-treatment changes in tumor and organ uptake of a radiolabeled anti PD-L1 antibody during chemoradiotherapy in patients with non-small cell lung cancer using whole body PET

Autor: Tanja D de Gruijl, Teodora Radonic, Marc C Huisman, Idris Bahce, Johanna E E Pouw, Sayed M S Hashemi, Jessica E Wijngaarden, Maarten Slebe, Daniela E Oprea-Lager, Gerben J C Zwezerijnen, Danielle Vugts, Ezgi B Ulas, Suresh Senan, C Willemien Menke-van der Houven van Oordt

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)

Background In patients with locally advanced unresectable non-small cell lung cancer (NSCLC), durvalumab, an anti-programmed cell death ligand-1 (PD-L1) antibody, has shown improved overall survival when used as consolidation therapy following concur

Externí odkaz: https://doaj.org/article/4b3a18abdb6f4a34986c4c57af3d9db7

Endoscopically placed fiducial markers for image-guided radiotherapy in preoperative gastric cancer: Technical feasibility and potential benefit

Autor: Margot Bleeker, Astrid van der Horst, Arjan Bel, Jan-Jakob Sonke, Jeanin E. van Hooft, R. E. Pouw, Maarten C.C.M. Hulshof

Publikováno v: Endoscopy International Open, Vol 11, Iss 09, Pp E866-E872 (2023)

Externí odkaz: https://doaj.org/article/555c87dec66a4bff8b211997940440e3

Vacuum-stent: A combination of endoscopic vacuum therapy and an intraluminal stent for treatment of esophageal transmural defects

Autor: Lisanne M. D. Pattynama, Wietse J. Eshuis, Mark I. van Berge Henegouwen, Jacques J. G. H. M. Bergman, Roos E. Pouw

Publikováno v: Frontiers in Surgery, Vol 10 (2023)

IntroductionEndoscopic vacuum therapy (EVT) has gained a greater role in management of transmural defects in the upper gastrointestinal (GI) tract, including anastomotic leakage and esophageal perforation (e.g. Boerhaave syndrome and iatrogenic cause

Externí odkaz: https://doaj.org/article/15669ee9417140e9baf3277b6e6fe87b

Towards a robust and compact deep learning system for primary detection of early Barrett’s neoplasia: Initial image‐based results of training on a multi‐center retrospectively collected data set

Autor: Kiki N. Fockens, Jelmer B. Jukema, Tim Boers, Martijn R. Jong, Joost A. van der Putten, Roos E. Pouw, Bas L. A. M. Weusten, Lorenza Alvarez Herrero, Martin H. M. G. Houben, Wouter B. Nagengast, Jessie Westerhof, Alaa Alkhalaf, Rosalie Mallant, Krish Ragunath, Stefan Seewald, Peter Elbe, Maximilien Barret, Jacobo Ortiz Fernández‐Sordo, Oliver Pech, Torsten Beyna, Fons van der Sommen, Peter H. de With, A. Jeroen de Groof, Jacques J. Bergman

Publikováno v: United European Gastroenterology Journal, 11(4), 324-336. SAGE Publications Inc.
Fockens, K N, Jukema, J B, Boers, T, Jong, M R, van der Putten, J A, Pouw, R E, Weusten, B L A M, Alvarez Herrero, L, Houben, M H M G, Nagengast, W B, Westerhof, J, Alkhalaf, A, Mallant, R, Ragunath, K, Seewald, S, Elbe, P, Barret, M, Ortiz Fernández-Sordo, J, Pech, O, Beyna, T, van der Sommen, F, de With, P H, de Groof, A J & Bergman, J J 2023, ' Towards a robust and compact deep learning system for primary detection of early Barrett’s neoplasia : Initial image-based results of training on a multi-center retrospectively collected data set ', United European Gastroenterology Journal, vol. 11, no. 4, pp. 324-336 . https://doi.org/10.1002/ueg2.12363

Introduction: Endoscopic detection of early neoplasia in Barrett's esophagus is difficult. Computer Aided Detection (CADe) systems may assist in neoplasia detection. The aim of this study was to report the first steps in the development of a CADe sys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fcc000e2d7b0049f882191e98f7ecca
https://doi.org/10.1002/ueg2.12363