Zobrazeno 1 - 10
of 112
pro vyhledávání: '"E. Peter Geiduschek"'
Autor:
Kelly-Anne F. Twist, E. Peter Geiduschek, Sergei Nechaev, Elizabeth A. Campbell, Seth A. Darst, Ann Hochschild, Padraig Deighan, Vikas Jain
Publikováno v:
Proceedings of the National Academy of Sciences. 108:19961-19966
Activated transcription of the bacteriophage T4 late genes, which is coupled to concurrent DNA replication, is accomplished by an initiation complex containing the host RNA polymerase associated with two phage-encoded proteins, gp55 (the basal promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf3df91fe76afe3f5d42b25178eb3a5
https://doi.org/10.1073/pnas.1113328108
https://doi.org/10.1073/pnas.1113328108
Autor:
E. Peter Geiduschek
Publikováno v:
Journal of Biological Chemistry. 285:25885-25892
Having been offered the opportunity to contribute one of the episodes of this series of personal history accounts, I have chosen to write about circumstances that led me to the start of the scientific path that I have followed for the past forty odd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c34ce33851a5be10ff0ff6854ed2234
https://doi.org/10.1074/jbc.x110.143867
https://doi.org/10.1074/jbc.x110.143867
Publikováno v:
Proceedings of the National Academy of Sciences. 107:6777-6781
Many archaea (including all the methanogens, nearly all euryarchaeotes, and some crenarchaeotes) use histones as components of the chromatin that compacts their genomes. The archaeal histones are homo- and heterodimers that pair on DNA to form tetras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960c1f3f2598af1aa00052ce5c74dd8a
https://doi.org/10.1073/pnas.1002360107
https://doi.org/10.1073/pnas.1002360107
Publikováno v:
Molecular Microbiology. 74:582-593
Summary Methanocaldococcus jannaschii Ptr2, a member of the Lrp/AsnC family of bacterial DNA-binding proteins, is an activator of its eukaryal-type core transcription apparatus. In Lrp-family proteins, an N-terminal helix–turn–helix DNA-binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05b861b5c8183f5dc750b0f5c40e1d5
https://doi.org/10.1111/j.1365-2958.2009.06884.x
https://doi.org/10.1111/j.1365-2958.2009.06884.x
Publikováno v:
Journal of Biological Chemistry. 281:14321-14329
The Brf1 subunit of the central RNA polymerase (pol) III transcription initiation factor TFIIIB is bipartite; its N-terminal TFIIB-related half is principally responsible for recruiting pol III to the promoter and for promoter opening near the transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7523055a1dd1c0c987454f295acf94b7
https://doi.org/10.1074/jbc.m601702200
https://doi.org/10.1074/jbc.m601702200
Autor:
Sergei Nechaev, E. Peter Geiduschek
Publikováno v:
The EMBO Journal. 25:1700-1709
The bacterial RNA polymerase (RNAP) recognizes promoters through sequence-specific contacts of its promoter-specificity components (sigma) with two DNA sequence motifs. Contacts with the upstream ('-35') promoter motif are made by sigma domain 4 atta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cc942df1c9adf948137c9bbe2f87b3
https://doi.org/10.1038/sj.emboj.7601069
https://doi.org/10.1038/sj.emboj.7601069
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15423-15428
Transcriptional regulation in the archaea involves a mosaic of DNA-binding proteins frequently (although not exclusively) of bacterial type, modulating a eukaryal-type core transcription apparatus. Methanocaldococcus jannaschii ( Mja ) Ptr2, a homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efe17b8c4522c642a240ea118dcc776
https://doi.org/10.1073/pnas.0508043102
https://doi.org/10.1073/pnas.0508043102
Publikováno v:
Proceedings of the National Academy of Sciences. 102:15406-15411
Transcription factor (TF) IIIB, the central transcription initiation factor of RNA polymerase III (pol III), is composed of three subunits, Bdp1, Brf1 and TATA-binding protein (TBP), all essential for normal function in vivo and in vitro . Brf1 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea328d28e585bb6deedb0c8496a9d380
https://doi.org/10.1073/pnas.0507653102
https://doi.org/10.1073/pnas.0507653102
Publikováno v:
Molecular Microbiology. 56:1397-1407
The relatively complex archaeal RNA polymerases are constructed along eukaryotic lines, and require two initiation factors for promoter recognition and specific transcription that are homologues of the RNA polymerase II TATA-binding protein and TFIIB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86bab4a065e25a8eadccfdfe9d52942
https://doi.org/10.1111/j.1365-2958.2005.04627.x
https://doi.org/10.1111/j.1365-2958.2005.04627.x
Autor:
E. Peter Geiduschek, Mohamed Ouhammouch, Anjana J. Simpson, Najib M. El-Sayed, Geoffrey Langham, Winfried Hausner
Publikováno v:
Molecular Microbiology. 56:625-637
The archaeal transcription apparatus is chimeric: its core components (RNA polymerase and basal factors) closely resemble those of eukaryotic RNA polymerase II, but the putative archaeal transcriptional regulators are overwhelmingly of bacterial type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda28e44f4c26709571d09166db15031
https://doi.org/10.1111/j.1365-2958.2005.04563.x
https://doi.org/10.1111/j.1365-2958.2005.04563.x