The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria

Autor: Mutafova-Yambolieva, Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Lauren E. Peri, Violeta N.

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9964

The bladder urothelium releases ATP into the lamina propria (LP) during filling, which can activate P2X receptors on afferent neurons and trigger the micturition reflex. Effective ATP concentrations are largely dependent on metabolism by membrane-bou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::b0656bed2bbaaf93894221194521e04f

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Role of detrusor PDGFRα+ cells in mouse model of cyclophosphamide-induced detrusor overactivity

Autor: Haeyeong Lee, Byoung H. Koh, Lauren E. Peri, Holly J. Woodward, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh

Publikováno v: Lee, H, Koh, B H, Peri, L E, Woodward, H J, Perrino, B A, Sanders, K M & Koh, S D 2022, ' Role of detrusor PDGFRα+ cells in mouse model of cyclophosphamide-induced detrusor overactivity ', Scientific Reports, vol. 12, no. 1, 5071 . https://doi.org/10.1038/s41598-022-09155-3

Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8595c6017a3ddea499c9c8851570385
https://www.pure.ed.ac.uk/ws/files/259220890/s41598_022_09155_3.pdf

Role of detrusor PDGFRα

Autor: Haeyeong, Lee, Byoung H, Koh, Lauren E, Peri, Holly J, Woodward, Brian A, Perrino, Kenton M, Sanders, Sang Don, Koh

Publikováno v: Scientific reports. 12(1)

Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55faebb31bd3f93c4b1b6d68d9a86670
https://pubmed.ncbi.nlm.nih.gov/35332235

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