Zobrazeno 1 - 10
of 500
pro vyhledávání: '"E. Pennington"'
Publikováno v:
Atmospheric Chemistry and Physics, Vol 21, Pp 5079-5100 (2021)
Volatile chemical products (VCPs) are an increasingly important source of anthropogenic reactive organic carbon (ROC) emissions. Among these sources are everyday items, such as personal care products, general cleaners, architectural coatings, pestici
Externí odkaz:
https://doaj.org/article/bddd6a1289ab49bd89cf9c42989bd457
Autor:
Christy W. LaFlamme, Cassandra Rastin, Soham Sengupta, Helen E. Pennington, Sophie J. Russ-Hall, Amy L. Schneider, Emily S. Bonkowski, Edith P. Almanza Fuerte, Talia J. Allan, Miranda Perez-Galey Zalusky, Joy Goffena, Sophia B. Gibson, Denis M. Nyaga, Nico Lieffering, Malavika Hebbar, Emily V. Walker, Daniel Darnell, Scott R. Olsen, Pandurang Kolekar, Mohamed Nadhir Djekidel, Wojciech Rosikiewicz, Haley McConkey, Jennifer Kerkhof, Michael A. Levy, Raissa Relator, Dorit Lev, Tally Lerman-Sagie, Kristen L. Park, Marielle Alders, Gerarda Cappuccio, Nicolas Chatron, Leigh Demain, David Genevieve, Gaetan Lesca, Tony Roscioli, Damien Sanlaville, Matthew L. Tedder, Sachin Gupta, Elizabeth A. Jones, Monika Weisz-Hubshman, Shamika Ketkar, Hongzheng Dai, Kim C. Worley, Jill A. Rosenfeld, Hsiao-Tuan Chao, Undiagnosed Diseases Network, Geoffrey Neale, Gemma L. Carvill, University of Washington Center for Rare Disease Research, Zhaoming Wang, Samuel F. Berkovic, Lynette G. Sadleir, Danny E. Miller, Ingrid E. Scheffer, Bekim Sadikovic, Heather C. Mefford
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sequence-based genetic testing identifies causative variants in ~ 50% of individuals with developmental and epileptic encephalopathies (DEEs). Aberrant changes in DNA methylation are implicated in various neurodevelopmental disorders but rem
Externí odkaz:
https://doaj.org/article/56ab879163324f04934308a670c8a49d
Autor:
Alexander C J, van Akkooi, Tina J, Hieken, Elizabeth M, Burton, Charlotte, Ariyan, Paolo A, Ascierto, Salvatore V M A, Asero, Christian U, Blank, Matthew S, Block, Genevieve M, Boland, Corrado, Caraco, Sydney, Chng, B Scott, Davidson, Joao Pedreira, Duprat Neto, Mark B, Faries, Jeffrey E, Gershenwald, Dirk J, Grunhagen, David E, Gyorki, Dale, Han, Andrew J, Hayes, Winan J, van Houdt, Giorgos C, Karakousis, Willem M C, Klop, Georgina V, Long, Michael C, Lowe, Alexander M, Menzies, Roger, Olofsson Bagge, Thomas E, Pennington, Piotr, Rutkowski, Robyn P M, Saw, Richard A, Scolyer, Kerwin F, Shannon, Vernon K, Sondak, Hussein, Tawbi, Alessandro A E, Testori, Mike T, Tetzlaff, John F, Thompson, Jonathan S, Zager, Charlotte L, Zuur, Jennifer A, Wargo, Andrew J, Spillane, Merrick I, Ross
Publikováno v:
Annals of Surgical Oncology, 29(6), 3694-3708. Springer New York
Exciting advances in melanoma systemic therapies have presented the opportunity for surgical oncologists and their multidisciplinary colleagues to test the neoadjuvant systemic treatment approach in high-risk, resectable metastatic melanomas. Here we
Autor:
Mary-Ann El Sharouni, Richard A. Scolyer, Carla H. van Gils, Sydney Ch’ng, Omgo E. Nieweg, Thomas E. Pennington, Robyn PM. Saw, Kerwin Shannon, Andrew Spillane, Jonathan Stretch, Arjen J. Witkamp, Vigfús Sigurdsson, John F. Thompson, Paul J. van Diest, Serigne N. Lo
Publikováno v:
European Journal of Cancer. 167:133-141
This study sought to assess whether the interval between diagnostic excision-biopsy of a primary melanoma and definitive wide excision with sentinel node biopsy (SNB) influenced the size of SN metastatic deposits, which might have implications for ma
Autor:
Richard A. Scolyer, Victoria Atkinson, David E. Gyorki, Duncan Lambie, Sandra O'Toole, Robyn P.M. Saw, Benhur Amanuel, Christopher M. Angel, Alison E. Button-Sloan, Matteo S. Carlino, Sydney Ch'ng, Andrew J. Colebatch, Dariush Daneshvar, Inês Pires da Silva, Tamara Dawson, Peter M. Ferguson, Erwin Foster-Smith, Stephen B. Fox, Anthony J. Gill, Ruta Gupta, Michael A. Henderson, Angela M. Hong, Julie R. Howle, Louise A. Jackett, Craig James, C. Soon Lee, Alistair Lochhead, Daphne Loh, Grant A. McArthur, Catriona A. McLean, Alexander M. Menzies, Omgo E. Nieweg, Blake H. O'Brien, Thomas E. Pennington, Alison J. Potter, Saurabh Prakash, Robert V. Rawson, Rebecca L. Read, Michael A. Rtshiladze, Kerwin F. Shannon, B. Mark Smithers, Andrew J. Spillane, Jonathan R. Stretch, John F. Thompson, Paul Tucker, Alexander H.R. Varey, Ricardo E. Vilain, Benjamin A. Wood, Georgina V. Long
Publikováno v:
Pathology. 54:6-19
Targeted therapy (BRAF inhibitor plus MEK inhibitor) is now among the possible treatment options for patients with BRAF mutation-positive stage III or stage IV melanoma. This makes prompt BRAF mutation testing an important step in the management of p
Autor:
Irene L. M. Reijers, Alexander M. Menzies, Alexander C. J. van Akkooi, Judith M. Versluis, Noëlle M. J. van den Heuvel, Robyn P. M. Saw, Thomas E. Pennington, Ellen Kapiteijn, Astrid A. M. van der Veldt, Karijn P. M. Suijkerbuijk, Geke A. P. Hospers, Elisa A. Rozeman, Willem M. C. Klop, Winan J. van Houdt, Karolina Sikorska, Jos A. van der Hage, Dirk J. Grünhagen, Michel W. Wouters, Arjen J. Witkamp, Charlotte L. Zuur, Judith M. Lijnsvelt, Alejandro Torres Acosta, Lindsay G. Grijpink-Ongering, Maria Gonzalez, Katarzyna Jóźwiak, Carolien Bierman, Kerwin F. Shannon, Sydney Ch’ng, Andrew J. Colebatch, Andrew J. Spillane, John B. A. G. Haanen, Robert V. Rawson, Bart A. van de Wiel, Lonneke V. van de Poll-Franse, Richard A. Scolyer, Annelies H. Boekhout, Georgina V. Long, Christian U. Blank
Publikováno v:
Nature Medicine, 28(6), 1178-+. NATURE PORTFOLIO
Nature Medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine
Nature medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine, 28. Nature Publishing Group
Nature Medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine
Nature medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine, 28. Nature Publishing Group
Neoadjuvant ipilimumab and nivolumab induces high pathologic response rates (pRRs) in clinical stage III nodal melanoma, and pathologic response is strongly associated with prolonged relapse-free survival (RFS). The PRADO extension cohort of the OpAC
Autor:
Daniel R. Schlaepfer, Kyle A. Taylor, Victoria E. Pennington, Kellen N. Nelson, Trace E. Martyn, Caitlin M. Rottler, William K. Lauenroth, John B. Bradford
Publikováno v:
Ecosphere, Vol 6, Iss 1, Pp 1-31 (2015)
Many semi‐arid plant communities in western North America are dominated by big sagebrush. These ecosystems are being reduced in extent and quality due to economic development, invasive species, and climate change. These pervasive modifications have
Externí odkaz:
https://doaj.org/article/ed87b815ac1b41798919314fbd4f4581
Autor:
Kerwin F. Shannon, Andrew T. Li, Serigne Lo, Georgina V. Long, Matteo S. Carlino, Alexander H. R. Varey, Andrew J. Spillane, Kavita Vakharia, Omgo E. Nieweg, Julie Howle, Jonathan R. Stretch, John F. Thompson, Thomas E. Pennington, Richard A. Scolyer, Robyn P. M. Saw, Sydney Ch'ng, Alexander M. Menzies
Publikováno v:
Annals of Surgical Oncology. 28:6109-6123
Metastasectomy for selected patients with melanoma was associated with improved survival in the era before effective systemic therapy. Emerging evidence shows that these benefits persist even in this era of BRAF-targeted therapy and immune checkpoint
Autor:
Christian U. Blank, Rodabe N. Amaria, Jennifer A. Wargo, Bart A. van de Wiel, Georgina V. Long, Hussein Abdul-Hassan Tawbi, Alexander C. Huang, Xiaowei Xu, Richard A. Scolyer, Tara C. Mitchell, Giorgos C. Karakousis, Alexander C.J. van Akkooi, Michael A. Davies, Andrew J. Spillane, Elisa A. Rozeman, Alexander M. Menzies, Robyn P. M. Saw, Michael T. Tetzlaff, Ahmad A. Tarhini, Thomas E. Pennington, Elizabeth M. Burton, Paolo A. Ascierto, Serigne Lo
Publikováno v:
Nature Medicine. 27:301-309
The association among pathological response, recurrence-free survival (RFS) and overall survival (OS) with neoadjuvant therapy in melanoma remains unclear. In this study, we pooled data from six clinical trials of anti-PD-1-based immunotherapy or BRA
Autor:
Victoria L.C. Pallares, Anna E. Pennington, Morgan L. Crowley, Avi Patel, Morgan E. Reeves, Carolina Lopera-Londoño, Marco Mottinelli, Nicholas P. Ho, Francisco León, John D. Fortner, Christopher R. McCurdy, Luis F. Restrepo, Victoria A. Taylor, Jenny L. Wilkerson, Lance R. McMahon, Samuel Obeng, Takato Hiranita, Tobias Braun, Lea R. Gamez-Jimenez, Morgan R. Williamson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:410-427
Relationships between µ-opioid receptor (MOR) efficacy and effects of mitragynine and 7-hydroxymitragynine are not fully established. We assessed in vitro binding affinity and efficacy and discriminative stimulus effects together with antinociceptio