Zobrazeno 1 - 10
of 103
pro vyhledávání: '"E. Padula"'
Autor:
Jacqueline S. Womersley, Clémence Obellianne, Audrey E. Padula, Marcelo F. Lopez, William C. Griffin, Lauren E. Ball, Stefano Berto, Kathleen A. Grant, Danyelle M. Townsend, Joachim D. Uys, Patrick J. Mulholland
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117514- (2024)
Alcohol use disorder (AUD) is the most prevalent substance use disorder but there is incomplete knowledge of the underlying molecular etiology. Here, we examined the cytosolic proteome from the nucleus accumbens core (NAcC) of ethanol drinking rhesus
Externí odkaz:
https://doaj.org/article/065fd24f7c074ee98ae105b126d2ddbc
Autor:
Patrick J. Mulholland, Audrey E. Padula, Larry J. Wilhelm, Byung Park, Kathleen A. Grant, Betsy M. Ferguson, Rita Cervera-Juanes
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The underlying genetic and epigenetic mechanisms driving functional adaptations in neuronal excitability and excessive alcohol intake are poorly understood. Small-conductance Ca2+-activated K+ (KCa2 or SK) channels encoded by the KCNN family
Externí odkaz:
https://doaj.org/article/0f5f2a56dec54ef883fca75ec810d00c
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Repeated exposure to ethanol followed by withdrawal leads to the alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (NAc) in both clinical and preclinical models of ethanol exposure. Homer2 is a member of
Externí odkaz:
https://doaj.org/article/1793eab71d0a48789bd4b08b9fd805c1
Autor:
Jennifer A. Rinker, Marcelo F. Lopez, Patrick J. Mulholland, Audrey E. Padula, Howard C. Becker, Robert W. Williams, Megan K. Mulligan
Publikováno v:
Translational Psychiatry
Mood disorders are often comorbid with alcohol use disorder (AUD) and play a considerable role in the development and maintenance of alcohol dependence and relapse. Because of this high comorbidity, it is necessary to determine shared and unique gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05f7782a212aead05555b8b562eff94
http://europepmc.org/articles/PMC7699620
http://europepmc.org/articles/PMC7699620
Autor:
Megan K. Mulligan, Marcelo F. Lopez, Robert W. Williams, Fauzan Khan, Audrey E. Padula, Patrick J. Mulholland, Jennifer A. Rinker, Howard C. Becker
Anxiety and mood disorders are often comorbid with alcohol use disorder (AUD) and are considered critical in the development, maintenance, and reinstatement of alcohol dependence and harmful alcohol-seeking behaviors. Because of this high comorbidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99efd6e9b0a94cb18e564cabee999715
Autor:
Marcelo F. Lopez, Patrick J. Mulholland, Reginald Cannady, Tiffany Nguyen, Howard C. Becker, John J. Woodward, Jennifer A. Rinker, Audrey E. Padula
Publikováno v:
Neuropharmacology
Stress is a risk factor that plays a considerable role in the development and maintenance of alcohol (ethanol) abuse and relapse. Preclinical studies examining ethanol-stress interactions have demonstrated elevated ethanol drinking, cognitive deficit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aae750a60ac5b2a4879a4a06b79a3bd
https://doi.org/10.1016/j.neuropharm.2020.108396
https://doi.org/10.1016/j.neuropharm.2020.108396
Autor:
William C. Griffin, Patrick J. Mulholland, Natalie S. McGuier, Audrey E. Padula, Elissa J. Chesler, Justin T. Gass
Publikováno v:
Addiction Biology. 21:1097-1112
Alcohol use disorders (AUDs) are a major public health issue and produce enormous societal and economic burdens. Current Food and Drug Administration (FDA)-approved pharmacotherapies for treating AUDs suffer from deleterious side effects and are only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f551b73fa65b442cb7d5747e4d3cd402
https://doi.org/10.1111/adb.12279
https://doi.org/10.1111/adb.12279
Autor:
Natalie S. McGuier, Patrick J. Mulholland, Audrey E. Padula, Marcelo F. Lopez, John J. Woodward
Publikováno v:
Alcohol. 49:21-27
Alcohol use disorders (AUDs) are associated with functional and morphological changes in subfields of the prefrontal cortex. Clinical and preclinical evidence indicates that the orbitofrontal cortex (OFC) is critical for controlling impulsive behavio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabe8eb56569c904e3a32a2f2fdc1cfa
https://doi.org/10.1016/j.alcohol.2014.07.017
https://doi.org/10.1016/j.alcohol.2014.07.017
Autor:
Natalie S, McGuier, William C, Griffin, Justin T, Gass, Audrey E, Padula, Elissa J, Chesler, Patrick J, Mulholland
Publikováno v:
Addiction biology. 21(6)
Alcohol use disorders (AUDs) are a major public health issue and produce enormous societal and economic burdens. Current Food and Drug Administration (FDA)-approved pharmacotherapies for treating AUDs suffer from deleterious side effects and are only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c718e09267a793eab79cff9ba3b59c00
https://pubmed.ncbi.nlm.nih.gov/26104325
https://pubmed.ncbi.nlm.nih.gov/26104325
Publikováno v:
Journal of Virology. 83:4757-4765
Herpes simplex virus 1 (HSV-1) nucleocapsids exit the nucleus by budding into the inner nuclear membrane, where they exist briefly as primary enveloped virions. These virus particles subsequently fuse their envelopes with the outer nuclear membrane,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e16a20f5f33995f45ade20d0ab738ad
https://doi.org/10.1128/jvi.01927-08
https://doi.org/10.1128/jvi.01927-08