Zobrazeno 1 - 10 of 28 pro vyhledávání: '"E. P. Reich"'
1
Treatment with Sulfatide or its Precursor, Galactosylceramide, Prevents Diabetes in NOD Mice
Autor: Pam Fredman, K Hanspers, Karsten Buschard, E P Reich
Publikováno v: Autoimmunity. 34:9-17
Sulfatide (3'sulfogalactosylceramide) is a glycosphingolipid present within the nervous system and in the islets of Langerhans. Anti-sulfatide antibodies have been observed in both pre-diabetic and newly diagnosed type 1 diabetic patients. The aim of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9bc359e956e274508e65f3920675d5
https://doi.org/10.3109/08916930108994121
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2
Synthesis and kinetics of cyclization of MHC class II-derived cyclic peptide vaccine for diabetes
Autor: L. Berezhkovskiy, E.-P. Reich, S. Deshpande, S. Pham
Publikováno v: The Journal of Peptide Research. 54:112-119
Conformationally constrained cyclic peptides are known to be better vaccines because of their ability to mimic the native structure of a protein against which an immune response is sought. To test the hypothesis of using conformationally constrained,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46173b7dae3b71b93b13e507c67383cd
https://doi.org/10.1034/j.1399-3011.1999.00084.x
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4
Self peptides isolated from MHC glycoproteins of non-obese diabetic mice
Autor: E P, Reich, H, von Grafenstein, A, Barlow, K E, Swenson, K, Williams, C A, Janeway
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 152(5)
The non-obese diabetic (NOD) mouse spontaneously develops an insulin-dependent diabetes mellitus that resembles human type I diabetes. This disease can be transferred by purified T cells or cloned T cell lines, implicating an autoimmune T cell attack
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46a1e73383283fbcf9d81ca91b11b890
https://pubmed.ncbi.nlm.nih.gov/8133041
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5
Rules for the Presentation of Peptides by Class II Molecules of the Major Histocompatibility Complex
Autor: J. Rothbard, E.-P. Reich, Basel K. al-Ramadi, Donal B. Murphy, Alexander Y. Rudensky, C. A. JanewayJr., Paula Preston-Hurlburt
Publikováno v: Progress in Immunology Vol. VIII ISBN: 9783642514814
As virtually all adaptive immune responses involve the activation of CD4 T cells by specific antigen, a central question in immunology is the nature of the ligands recognized by these cells. It is now well established that CD4 T cells respond to pept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2338dce6800514550b9cfc484818c98
https://doi.org/10.1007/978-3-642-51479-1_24
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6
Cross-linking and Conformational Change in T-cell Receptors: Role in Activation and in Repertoire Selection
Autor: J. Yagi, Charles A Janeway, E.-P. Reich, U. Dianzani, J. M. Rojo, Donal B. Murphy, S. Rath, P. Portoles
Publikováno v: Cold Spring Harbor Symposia on Quantitative Biology. 54:657-666
TCRs undergo a series of interactions with ligands during development. We have characterized the interaction of a TCR with its ligand and the attendant co-receptor and co-ligand structures. This characterization has led to the model in which the TCR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16a23fb8406d8bb1fbd4411c34fd9d8
https://doi.org/10.1101/sqb.1989.054.01.077
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7
Autocrine growth of CD4+ T cells. Differential effects of IL-1 on helper and inflammatory T cells
Autor: L A Greenbaum, J B Horowitz, A Woods, T Pasqualini, E P Reich, K Bottomly
Publikováno v: The Journal of Immunology. 140:1555-1560
The growth factor requirements of cloned lines representing two major subsets of CD4+ T cells were examined. The helper subset, which produces IL-4 as its autocrine growth factor, proliferates in response to IL-2 or to IL-4 in the presence of IL-1. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a16d15eed6b95db3559c9e71b726b183
https://doi.org/10.4049/jimmunol.140.5.1555
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9
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10
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