Zobrazeno 1 - 10
of 57
pro vyhledávání: '"E. P. PAPADOPOULOS"'
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Reversible phosphorylation is the basis for signal transduction in eukaryotic cells, and this is tightly controlled by the complex interplay of kinases and phosphatases. Many malignancies are characterized by dysregulation of the delicate protein pho
Externí odkaz:
https://doaj.org/article/01d3318abf6e40219aedb51d5194df09
Publikováno v:
Journal of Heterocyclic Chemistry. 40:885-893
The triethylamine-catalyzed reactions of methyl N-(cyanothioformyl)anthranilate (1) with isocyanates result in cyclization involving the cyano group to form methyl 2-(4-imino-2-oxo-3-substituted-5-thioxoimi-dazolidin-1-yl)benzoates (4). Ring closure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a111b26ddfd0831596e2f49ca6d2f021
https://doi.org/10.1002/jhet.5570400522
https://doi.org/10.1002/jhet.5570400522
Publikováno v:
Journal of Heterocyclic Chemistry. 38:343-347
A variety of 2-substituted thiophenes is readily obtained from 2-(2-thienyl)-4H-3,l-benzothiazin-4-one (2), which is formed when thiophene reacts with methyl 2-isothiocyanatobenzoate (1) in the presence of anhydrous stannic chloride.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c90ce4675981ba9aed241155f26cb6f
https://doi.org/10.1002/jhet.5570380204
https://doi.org/10.1002/jhet.5570380204
Autor:
L. M. Deck, E. P. Papadopoulos
Publikováno v:
Journal of Heterocyclic Chemistry. 37:675-680
The ureas 3 which are obtained from 3-(benzylamino)propanenitrile (1) and various isocyanates (2) cyclize readily upon heating in ethanol, in the presence of hydrochloric acid, to form 3-substituted 1-benzyldihydro-2,4-(1H,3H)pyrimidinediones (11) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e9a4b9034a097e0709e6016813399d6
https://doi.org/10.1002/jhet.5570370401
https://doi.org/10.1002/jhet.5570370401
Publikováno v:
ChemInform. 32
A variety of 2-substituted thiophenes is readily obtained from 2-(2-thienyl)-4H-3,l-benzothiazin-4-one (2), which is formed when thiophene reacts with methyl 2-isothiocyanatobenzoate (1) in the presence of anhydrous stannic chloride.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c978446e52492a0389bdf93ae3b5c6
https://doi.org/10.1002/chin.200136114
https://doi.org/10.1002/chin.200136114
Publikováno v:
ChemInform. 35
The triethylamine-catalyzed reactions of methyl N-(cyanothioformyl)anthranilate (1) with isocyanates result in cyclization involving the cyano group to form methyl 2-(4-imino-2-oxo-3-substituted-5-thioxoimi-dazolidin-1-yl)benzoates (4). Ring closure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bef4d5206e67932952e0ad6b7c20e67
https://doi.org/10.1002/chin.200412045
https://doi.org/10.1002/chin.200412045
Autor:
E. P. Papadopoulos, L. M. Deck
Publikováno v:
ChemInform. 32
The ureas 3 which are obtained from 3-(benzylamino)propanenitrile (1) and various isocyanates (2) cyclize readily upon heating in ethanol, in the presence of hydrochloric acid, to form 3-substituted 1-benzyldihydro-2,4-(1H,3H)pyrimidinediones (11) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dd6289c7d626e5f8259f90313287711
https://doi.org/10.1002/chin.200101161
https://doi.org/10.1002/chin.200101161
Autor:
E. P. Papadopoulos, L. L. Whitfield
Publikováno v:
Synthesis. 1985:423-426
Le compose du titre reagit avec des amines ou des alcanols-1: obtention des dialkylthiocarbamoylamides ou alcoxythiocarbonylamides et esters de methyle de l'acide phtalique; l'action de l'hydrazine sur les alcoxythiocarbonylamides conduit aux s-triaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0849cd9fee6ddb310674134302cc1a
https://doi.org/10.1055/s-1985-31227
https://doi.org/10.1055/s-1985-31227
Autor:
E. P. Papadopoulos
Publikováno v:
The Journal of Organic Chemistry. 41:962-965
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a41ace431429e0253f705fbd79ccd96
https://doi.org/10.1021/jo00868a013
https://doi.org/10.1021/jo00868a013
Autor:
E. P. Papadopoulos
Publikováno v:
Journal of Heterocyclic Chemistry. 21:1411-1414
The urea 1 obtained from anthranilonitrile and 3-chloropropyl isocyanate is converted into 3-(3-chloropropyl)-2,4(1H,3H)quinazolinedione (4) when heated with hydrochloric acid, whereas it undergoes a double cyclization to form 2,3,4,7-tetrahydro-6H-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce8c83a62c5f2f0ef5d01074c2f93ee
https://doi.org/10.1002/jhet.5570210537
https://doi.org/10.1002/jhet.5570210537