Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E. P. K. Mensah-Brown"'
Autor:
Suraiya A. Ansari, Ernesto Guccione, Princy Jayaprakash, Suneesh Kaimala, Sreejisha P Sreedharan, E. P. K. Mensah-Brown, Bright Starling Emerald, Ernest Adeghate, Jimsheena V. Karakkat
Publikováno v:
Nucleic Acids Research
The metabolic sensor Per-Arnt-Sim (Pas) domain-containing serine/threonine kinase (PASK) is expressed predominantly in the cytoplasm of different cell types, although a small percentage is also expressed in the nucleus. Herein, we show that the nucle
Publikováno v:
Clinical Epigenetics
Diabetes mellitus (DM) is a chronic condition characterised by β cell dysfunction and persistent hyperglycaemia. The disorder can be due to the absence of adequate pancreatic insulin production or a weak cellular response to insulin signalling. Amon
Autor:
Basel K. al-Ramadi, Maria J. Fernandez-Cabezudo, Yousef Haik, E. P. K. Mensah-Brown, Shahnaz Qadri, Ghada Bashir
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:2241-2250
Treatment of osteomyelitis by conventional antibiotics has proven to be challenging due to limited accessibility to this unique location. Inorganic routes against bacterial infection have been reported for external and topical applications, however i
Autor:
E. P. K. Mensah-Brown, Suraiya A. Ansari, Bright Starling Emerald, Ahmed Hassan Al-Marzouqi, Ranjit Vijayan, Suneesh Kaimala, Marwa F Ibrahim, Jimsheena V. Karakkat, Ashok Daniel Prabakaran, Ernest Adeghate, Jisha Chalissery
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 3 (2018)
Disease Models & Mechanisms, Vol 11, Iss 3 (2018)
Although the existence of a close relationship between the early maternal developmental environment, fetal size at birth and the risk of developing disease in adulthood has been suggested, most studies, however, employed experimentally induced intrau
Autor:
Mustafa T. Ardah, E. P. K. Mensah-Brown, Divya S. Varghese, Ashok Daniel Prabakaran, Bright Starling Emerald, Shama Parween, Suraiya A. Ansari
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The nutrient responsive O-GlcNAcylation is a dynamic post-translational protein modification found on several nucleocytoplasmic proteins. Previous studies have suggested that hyperglycemia induces the levels of total O-GlcNAcylation inside the cells.
Autor:
Mariam Al-Shamsi, Suleiman Al-Hammadi, Abdul-Kader Souid, Allen Shahin, E. P. K. Mensah-Brown, Aysha Al-Mansouri, Farida Marzouqi
Publikováno v:
Sultan Qaboos University Medical Journal. 14:65-71
Objectives: Aflatoxin B 1 (AFB 1 ) is a naturally occurring carcinogenic and immunosuppressive compound. This study was designed to measure its toxic effects on human peripheral blood mononuclear cells (PBMC). Methods: The study recruited 7 healthy v
Publikováno v:
Clinical Immunology. 149:86-96
Toll like receptors are primary sensors of both innate and adaptive immune systems. They activate APCs and influence T-cell function in inflammatory autoimmune response. Studies have shown that TLR manipulation may lead to either tolerance or trigger
Autor:
Xiang-Yu Zheng, E. P. K. Mensah-Brown, Jie Zhu, Sheikh Azimullah, Mariam Al Shamsi, Hong-Liang Zhang, Naheed Amir, Xiaoke Wang, Abdu Adem, Allen Shahin, Rayomand Press
Publikováno v:
Journal of Neuroimmunology. 246:18-26
Previous studies have shown that interferon-gamma (IFN-γ) is a proinflammatory cytokine that contributes to the pathogenesis of Guillain–Barre syndrome and its animal model, experimental autoimmune neuritis (EAN). Treatments with anti-IFN-γ antib
Autor:
Nebojsa Arsenijevic, E. P. K. Mensah-Brown, Miodrag L. Lukic, Allen Shahin, Nemanja Zdravkovic
Publikováno v:
Molecular Immunology. 47:28-36
Several peripheral mechanisms appear to be operational in limiting autoimmune damage of the islets of Langerhans and organ-specific T cell-mediated autoimmunity in general. These include cyclophosphamide sensitive T regulatory cells (Treg cells) and
Autor:
Carl S. Goodyear, Sandra Y. Fukada, Fu-Tong Liu, Zakeya Al Rasebi, Hui-Rong Jiang, Allen Shahin, Damo Xu, Miodrag L. Lukic, E. P. K. Mensah-Brown, Foo Y. Liew
Publikováno v:
The Journal of Immunology. 182:1167-1173
Galectin-3 (Gal-3) is a member of the β-galactoside-binding lectin family and plays an important role in inflammation. However, the precise role of Gal-3 in autoimmune diseases remains obscure. We have investigated the functional role of Gal-3 in ex