Zobrazeno 1 - 7
of 7
pro vyhledávání: '"E. P. Baxter"'
Autor:
Zijian Fang, Giuditta Corbizi Fattori, Thomas McKerrell, Rebecca H. Boucher, Aimee Jackson, Rachel S. Fletcher, Dorian Forte, Jose-Ezequiel Martin, Sonia Fox, James Roberts, Rachel Glover, Erica Harris, Hannah R. Bridges, Luigi Grassi, Alba Rodriguez-Meira, Adam J. Mead, Steven Knapper, Joanne Ewing, Nauman M. Butt, Manish Jain, Sebastian Francis, Fiona J. Clark, Jason Coppell, Mary F. McMullin, Frances Wadelin, Srinivasan Narayanan, Dragana Milojkovic, Mark W. Drummond, Mallika Sekhar, Hesham ElDaly, Judy Hirst, Maike Paramor, E. Joanna Baxter, Anna L. Godfrey, Claire N. Harrison, Simón Méndez-Ferrer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Current therapies for myeloproliferative neoplasms (MPNs) improve symptoms but have limited effect on tumor size. In preclinical studies, tamoxifen restored normal apoptosis in mutated hematopoietic stem/progenitor cells (HSPCs). TAMARIN Pha
Externí odkaz:
https://doaj.org/article/16a1a95232b2462f94a84a299c0e1020
Autor:
Heather E. Machado, Nina F. Øbro, Nicholas Williams, Shengjiang Tan, Ahmed Z. Boukerrou, Megan Davies, Miriam Belmonte, Emily Mitchell, E. Joanna Baxter, Nicole Mende, Anna Clay, Philip Ancliff, Jutta Köglmeier, Sally B. Killick, Austin Kulasekararaj, Stefan Meyer, Elisa Laurenti, Peter J. Campbell, David G. Kent, Jyoti Nangalia, Alan J. Warren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Clonal tracking of cells using somatic mutations permits exploration of clonal dynamics in human disease. Here, we perform whole genome sequencing of 323 haematopoietic colonies from 10 individuals with the inherited ribosomopathy Shwachman-
Externí odkaz:
https://doaj.org/article/83d4535580c848179ab239f1596e4673
Autor:
Aleksandra Kamizela, Nicholas Williams, Joe Lee, Karim Mane, Kate Milne, Tony Green, Timothy Chevassut, Brian Huntly, E. Joanna Baxter, Jyoti Nangalia
Publikováno v:
HemaSphere, Vol 7, p e82325b5 (2023)
Externí odkaz:
https://doaj.org/article/15786b79c5f34ba6872f1edc79b90809
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 22, Iss 9, Pp n/a-n/a (2021)
Abstract The presence of mélange at the subduction interface influences numerous geochemical and geophysical processes. However, the relationship between the timescales of mélange development, deformation, and resultant mass transport is poorly und
Externí odkaz:
https://doaj.org/article/17e37bbbd7cb4259aa77a396cca36060
Autor:
Rachel Dobson, Peter Y. Du, Lívia Rásó-Barnett, Wen-Qing Yao, Zi Chen, Calogero Casa, Hesham EI-Daly, Lorant Farkas, Elizabeth Soilleux, Penny Wright, John W. Grant, Manuel Rodriguez-Justo, George A. Follows, Hala Rashed, Margarete Fabre, E. Joanna Baxter, George Vassiliou, Andrew Wotherspoon, Ayoma D. Attygalle, Hongxiang Liu, Ming-Qing Du
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma with T follicular helper phenotype (PTCL-TFH) are a group of complex clinicopathological entities that originate from T follicular helper cells and share a similar mutation prof
Externí odkaz:
https://doaj.org/article/252c4c971bfc4266a313e8ba0c9f2647
Autor:
Nina F. Øbro, Jacob Grinfeld, Miriam Belmonte, Melissa Irvine, Mairi S. Shepherd, Tata Nageswara Rao, Axel Karow, Lisa M. Riedel, Oliva B. Harris, E. Joanna Baxter, Jyoti Nangalia, Anna Godfrey, Claire N. Harrison, Juan Li, Radek C. Skoda, Peter J. Campbell, Anthony R. Green, David G. Kent
Publikováno v:
HemaSphere, Vol 4, Iss 3, p e371 (2020)
Abstract. Myeloproliferative neoplasms (MPNs) are characterized by deregulation of mature blood cell production and increased risk of myelofibrosis (MF) and leukemic transformation. Numerous driver mutations have been identified but substantial disea
Externí odkaz:
https://doaj.org/article/43e4a632d24a477996c58eecfcde097c
Publikováno v:
Immunology letters. 25(1-3)
Multiple sclerosis (MS) is a common cause of neurological disability in young adults. The disease generally manifests in early to middle adulthood and causes various neurological deficits. Autoreactive T lymphocytes and their associated antigens have