Zobrazeno 1 - 10
of 41
pro vyhledávání: '"E. Osler"'
Autor:
Gustavo A. Nader, Alexander V. Chibalin, Brendan Egan, Isabelle Riedl, Marie Björnholm, Juleen R. Zierath, Megan E. Osler
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 310:E461-E472
Mechanisms regulating skeletal muscle growth involve a balance between the activity of serine/threonine protein kinases, including the mammalian target of rapamycin (mTOR) and 5′-AMP-activated protein kinase (AMPK). The contribution of different AM
Autor:
B. Arda Ozilgen, Daniella E. Duque-Guimaraes, Lake Q. Jiang, Juleen R. Zierath, Julie Massart, Megan E. Osler, Lars Löfgren, Alexander V. Chibalin, Atul S. Deshmukh, Thais de Castro Barbosa
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 310:E51-E60
Decrease of AMPK-related signal transduction and insufficient lipid oxidation contributes to the pathogenesis of obesity and type 2 diabetes. Previously, we identified that diacylglycerol kinase-δ (DGKδ), an enzyme involved in triglyceride biosynth
Autor:
Jörgen Östling, Pablo Garrido Cuesta, Mutsumi Katayama, Thais de Castro Barbosa, Ann-Christin Nyström, Lubna Al-Khalili, Julie Massart, Megan E. Osler, Juleen R. Zierath, Jan Oscarsson
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C774-C787
Two-dimensional difference gel electrophoresis (2-D DIGE)-based proteome analysis has revealed intrinsic insulin resistance in myotubes derived from type 2 diabetic patients. Using 2-D DIGE-based proteome analysis, we identified a subset of insulin-r
Publikováno v:
Mechanics & Industry. 15:169-174
Since a few years, a new wind measurement instrument has been competing with standard cup anemometers: the LiDAR. The performances of this instrument over complex terrain are still a matter of debate and this is mainly due to the flow homogeneity ass
Autor:
Tomas Fritz, Ferenc Szekeres, Anna Krook, Fredirick Mashili, Megan E. Osler, Petra Lundström, C.-G. Östenson, Juleen R. Zierath, Per Wändell, Kenneth Caidahl
Publikováno v:
Diabetes/Metabolism Research and Reviews. 29:25-32
Background Physical activity remains a valuable prevention for metabolic disease. The effects of Nordic walking on cardiovascular risk factors were determined in overweight individuals with normal or disturbed glucose regulation. Methods We included
Autor:
Megan E. Osler, Kenneth Caidahl, Romain Barrès, Anna Rune, Anna Krook, Jie Yan, Tomas Fritz, Juleen R. Zierath
Publikováno v:
Cell Metabolism. 10:189-198
Epigenetic modification through DNA methylation is implicated in metabolic disease. Using whole-genome promoter methylation analysis of skeletal muscle from normal glucose-tolerant and type 2 diabetic subjects, we identified cytosine hypermethylation
Publikováno v:
Annales de cardiologie et d'angeiologie. 66(1)
The history of infective endocarditis (IE) is a good example of medical progress. Initially incurable, endocarditis, when diagnosed, was synonym of death. After significant diagnostic progress, thanks to Osler's contribution especially, the first sur
Autor:
Heike Vogel, Sarah Voisin, Helgi B. Schiöth, Suzanne L. Dickson, Jonathan Cedernaes, Christian Benedict, Juleen R. Zierath, Megan E. Osler, Jan-Erik Broman
Publikováno v:
The Journal of clinical endocrinology and metabolism. 100(9)
Context: Shift workers are at increased risk of metabolic morbidities. Clock genes are known to regulate metabolic processes in peripheral tissues, eg, glucose oxidation. Objective: This study aimed to investigate how clock genes are affected at the
Publikováno v:
Proceedings of the National Academy of Sciences. 103:614-619
Bves/pop1a is a unique, highly conserved integral membrane protein expressed in embryonic epithelia and striated muscle. Although studies have proposed a role in epithelial morphogenesis, the function of Bves/pop1a in development is completely unknow
Autor:
David M. Bader, Megan E. Osler
Publikováno v:
Developmental Dynamics. 229:658-667
Bves (blood vessel/epicardial substance) is a transmembrane protein postulated to play a role in cell adhesion. While it is clear that Bves and gene products of the same family are expressed in adult striated muscle cells, the distribution of these p