Zobrazeno 1 - 10
of 547
pro vyhledávání: '"E. Noll"'
Autor:
Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract We implicated the X-chromosome THOC2 gene, which encodes the largest subunit of the highly-conserved TREX (Transcription-Export) complex, in a clinically complex neurodevelopmental disorder with intellectual disability as the core phenotype.
Externí odkaz:
https://doaj.org/article/f655e25df84a4da1addb5bf08b495565
Autor:
Tao Zhang, Sarah E. Noll, Jesus T. Peng, Amman Klair, Abigail Tripka, Nathan Stutzman, Casey Cheng, Richard N. Zare, Alexandra J. Dickinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Understanding how plants grow is critical for agriculture and fundamental for illuminating principles of multicellular development. Here, we apply desorption electrospray ionization mass spectrometry imaging (DESI-MSI) to the chemical mappin
Externí odkaz:
https://doaj.org/article/5cc3e1f00a584ee393fc975ae7acb806
Autor:
Hadil A. Alkathiry, Samia Q. Alghamdi, Holly E.J. Morgan, Madeleine E. Noll, Jing J. Khoo, Abdulaziz N. Alagaili, Benjamin L. Makepeace
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 2, Pp 402-406 (2023)
Scrub typhus is a zoonosis caused by 3 species of Orientia bacteria, including Candidatus Orientia chuto. This species is known only from a human case in Dubai and infections in wildlife in Kenya. We report molecular detection of Candidatus O. chuto
Externí odkaz:
https://doaj.org/article/dfb47a5d62314159a08485b20363ea09
Autor:
Alanah L. Bradey, Stephen Fitter, Jvaughn Duggan, Vicki Wilczek, Connor M. D. Williams, Emma AJ. Cheney, Jacqueline E. Noll, Pawanrat Tangseefa, Vasilios Panagopoulos, Andrew C. W. Zannettino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Multiple myeloma (MM) is an incurable haematological malignancy, caused by the uncontrolled proliferation of plasma cells within the bone marrow (BM). Obesity is a known risk factor for MM, however, few studies have investigated the potentia
Externí odkaz:
https://doaj.org/article/6d46703cea084e25a8d12c7d74c265bf
Autor:
Brea K Hampton, Kenneth S Plante, Alan C Whitmore, Colton L Linnertz, Emily A Madden, Kelsey E Noll, Samuel P Boyson, Breantie Parotti, James G Xenakis, Timothy A Bell, Pablo Hock, Ginger D Shaw, Fernando Pardo-Manuel de Villena, Martin T Ferris, Mark T Heise
Publikováno v:
PLoS Genetics, Vol 18, Iss 12, p e1010548 (2022)
Variation in immune homeostasis, the state in which the immune system is maintained in the absence of stimulation, is highly variable across populations. This variation is attributed to both genetic and environmental factors. However, the identity an
Externí odkaz:
https://doaj.org/article/15976cb8c23a4cb6bff3f652de673521
Autor:
Zhice Hu, Kenneth E. Noll
Publikováno v:
Atmosphere, Vol 14, Iss 10, p 1485 (2023)
This article delineates the characterization of traffic-induced turbulent kinetic energy (TKE) in areas proximate to roadways using real-world traffic conditions. Traffic-induced TKE serves as a pivotal tool to refine the parameters of eddy diffusivi
Externí odkaz:
https://doaj.org/article/33d36a15e8704e6bbb9528ec075aea1c
Autor:
Natasha L. Friend, Duncan R. Hewett, Vasilios Panagopoulos, Jacqueline E. Noll, Kate Vandyke, Krzysztof M. Mrozik, Stephen Fitter, Andrew C.W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 9, Pp 554-572 (2020)
Abstract The protein SAMSN1 was recently identified as a putative tumor suppressor in multiple myeloma, with re‐expression of Samsn1 in the 5TGM1/KaLwRij murine model of myeloma leading to a near complete abrogation of intramedullary tumor growth.
Externí odkaz:
https://doaj.org/article/156a98f254f24fe5bd74506dfb885296
Autor:
Krzysztof M. Mrozik, Chee M. Cheong, Duncan R. Hewett, Jacqueline E. Noll, Khatora S. Opperman, Alaknanda Adwal, Darryl L. Russell, Orest W. Blaschuk, Kate Vandyke, Andrew C. W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 6, Pp 339-353 (2020)
Abstract N‐cadherin is a homophilic cell‐cell adhesion molecule that plays a critical role in maintaining vascular stability and modulating endothelial barrier permeability. Pre‐clinical studies have shown that the N‐cadherin antagonist pepti
Externí odkaz:
https://doaj.org/article/c6826197d1b54a479b78471d9ab82b5d
Autor:
Jonathan Tucci, Ting Chen, Katherine Margulis, Etan Orgel, Rebecca L. Paszkiewicz, Michael D. Cohen, Matthew J. Oberley, Rachel Wahhab, Anthony E. Jones, Ajit S. Divakaruni, Cheng-Chih Hsu, Sarah E. Noll, Xia Sheng, Richard N. Zare, Steven D. Mittelman
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThere is increasing evidence that adipocytes play an active role in the cancer microenvironment. We have previously reported that adipocytes interact with acute lymphoblastic leukemia (ALL) cells, contributing to chemotherapy resistance and
Externí odkaz:
https://doaj.org/article/a6c22b32684a48d097ddadfb7d3deaf1
Autor:
Kelsey E. Noll, Alan C. Whitmore, Ande West, Mary K. McCarthy, Clayton R. Morrison, Kenneth S. Plante, Brea K. Hampton, Heike Kollmus, Carolin Pilzner, Sarah R. Leist, Lisa E. Gralinski, Vineet D. Menachery, Alexandra Schäfer, Darla Miller, Ginger Shaw, Michael Mooney, Shannon McWeeney, Fernando Pardo-Manuel de Villena, Klaus Schughart, Thomas E. Morrison, Ralph S. Baric, Martin T. Ferris, Mark T. Heise
Publikováno v:
Cell Reports, Vol 31, Iss 4, Pp - (2020)
Summary: Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the Collaborative Cross (CC), a mouse genetic reference population, to study genetic regulati
Externí odkaz:
https://doaj.org/article/19d188bf28dc4ed39c07dd53afa84de9