Zobrazeno 1 - 10
of 51
pro vyhledávání: '"E. Nerland"'
Autor:
Donald E. Nerland
Publikováno v:
Drug Metabolism Reviews. 39:235-248
Cells exposed to oxidative stress or electrophilic xenobiotics respond by transcriptionally up-regulating a battery of genes that contain a cis-acting element in their promoter region known as the antioxidant/electrophile response element (ARE). Muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60ab0f323340685273785ba712843d8
https://doi.org/10.1080/03602530601125000
https://doi.org/10.1080/03602530601125000
Autor:
B. Kjølhamar, Daniel Baltar, Pål T. Gabrielsen, S. Fanavoll, R. Svendsen, E. Nerland, Kim Senger
Publikováno v:
Third EAGE Workshop on Rock Physics.
In frontier exploration, explorationists often struggle with lack of information, particularly due to lack of well data. Exploration thus relies primarily on elastic (e.g., 2D/3D seismic) and electric (e.g., 3D controlled-source electromagnetic surve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8611a0ebfa86d7994bf6ec90a9fda8
https://doi.org/10.3997/2214-4609.201414404
https://doi.org/10.3997/2214-4609.201414404
Publikováno v:
Fundamental and Applied Toxicology. 36:141-148
Three markers of acute acrylonitrile (AN) intoxication, namely, tissue glutathione (GSH), tissue cyanide (CN), and covalent binding to tissue protein, were studied as a function of dose and time. Doses administered and responses expected were 20 mg/k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c39df8d76ea1214f962ca2fd057aa0a
https://doi.org/10.1006/faat.1997.2294
https://doi.org/10.1006/faat.1997.2294
Publikováno v:
Toxicological Sciences. 36:141-148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::929649fc3c98da10c712a646edda9a4c
https://doi.org/10.1093/toxsci/36.2.141
https://doi.org/10.1093/toxsci/36.2.141
Autor:
Michael S. Wells, Donald E. Nerland
Publikováno v:
Toxicology Letters. 56:159-166
Benzene is metabolized to one or more hematotoxic species. Saturation of benzene metabolism could limit the production of toxic species. Saturation of phase II enzymes involved in the conjugation of the phenolic metabolites of benzene also could affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330f167821d54cf98ba3f44db8d13497
https://doi.org/10.1016/0378-4274(91)90102-c
https://doi.org/10.1016/0378-4274(91)90102-c
Publikováno v:
Molecular carcinogenesis. 45(4)
N-acetyltransferase 1 (NAT1) and 2 (NAT2) enzymes catalyzing both deactivation (N-acetylation) and activation (O-acetylation) of arylamine carcinogens such as 4-aminobiphenyl (ABP) were investigated in a Syrian hamster model congenic at the NAT2 locu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515b6a856eca000746f91ae758252915
https://pubmed.ncbi.nlm.nih.gov/16482518
https://pubmed.ncbi.nlm.nih.gov/16482518
Autor:
Frederick W. Benz, Donald E. Nerland
Publikováno v:
Archives of toxicology. 79(10)
Some of the more striking expressions of toxicity are the tremors and seizures observed approximately 100 min after exposure of rats to an acutely toxic dose of acrylonitrile (AN). These early events are followed by a second wave of severe clonic con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3e994e30563bc47b6095169cd08df4
https://pubmed.ncbi.nlm.nih.gov/15864551
https://pubmed.ncbi.nlm.nih.gov/15864551
Publikováno v:
Chemical research in toxicology. 16(5)
Covalent binding of reactive chemical species to tissue proteins is a common, but poorly understood, mechanism of toxicity. Identification of the proteins and the specific amino acid residues within the proteins that are chemically modified will aid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64cc72bf1b654d35daf9e687597adc2
https://pubmed.ncbi.nlm.nih.gov/12755587
https://pubmed.ncbi.nlm.nih.gov/12755587
Publikováno v:
Chemical research in toxicology. 14(7)
Acrylonitrile (AN) is an industrial vinyl monomer that is acutely toxic. When administered to rats, AN covalently binds to tissue proteins in a dose-dependent but nonlinear manner [Benz, F. W., Nerland, D. E., Li, J., and Corbett, D. (1997) Fundam. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12db832646df4829afea9496ac146c9
https://pubmed.ncbi.nlm.nih.gov/11453725
https://pubmed.ncbi.nlm.nih.gov/11453725
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 36(2)
LI, J., AND CORBETT, D. (1997). Fundam. Appl. ToxicoL 36, 149-156. The dose dependence of acrylonitrile (AN) covalent binding to tissue protein, following a single acute exposure over a 100-fold range in dose, was measured. Covalent binding was a lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51253d55011d8510aa6b714f70d62af8
https://pubmed.ncbi.nlm.nih.gov/9143484
https://pubmed.ncbi.nlm.nih.gov/9143484