Zobrazeno 1 - 10
of 38
pro vyhledávání: '"E. N. Ulomskii"'
Publikováno v:
Chimica Techno Acta, Vol 2, Iss 3, Pp 234-246 (2015)
Chimica Techno Acta; Том 2, № 3 (2015); 234-246
Chimica Techno Acta; Том 2, № 3 (2015); 234-246
As a model of metabolic transformations of antiviral drug “Triazaverin” and its analogues‑2-alkylthio‑6-nitro‑1,2,4-triazolo[5,1-c][1,2,4]triazine‑7-ones 1a-d examined the oxidation of alkylthio groups to the corresponding sulfoxides 2a-d
Autor:
Gennady L. Rusinov, Maksim L. Isenov, Evgeny B. Gorbunov, E. N. Ulomskii, Valery N. Charushin
Publikováno v:
Chemistry of Heterocyclic Compounds. 51:491-495
6-Nitroazolo[1,5-а]pyrimidines were used as dipolarophiles in a reaction with sodium azide providing previously unknown 2Н-azolo[1,5-а]-[1,2,3]triazolo[4,5-е]pyrimidines.
Autor:
Oleg N. Chupakhin, E. N. Ulomskii, Igor A. Khalymbadzha, G. L. Rusinov, Vladimir L. Rusinov, O. S. El´tsov, Victor G. Kartsev, Evgeny B. Gorbunov, V. N. Charushin
Publikováno v:
Chem. Nat. Compd.
Chemistry of Natural Compounds
Chemistry of Natural Compounds
The work was sponsored by the Russian Science Foundation (Project 14-13-01301).
Autor:
A. N. Korovina, Inna L. Karpenko, T. S. Shestakova, Galegov Ga, V.L. Andronova, Vladimir L. Rusinov, Oleg N. Chupakhin, Anastasia L. Khandazhinskaya, Marina K. Kukhanova, Sergey L. Deev, Maxim V. Yasko, E. N. Ulomskii
Publikováno v:
Bioorganic Chemistry. 38:265-270
A new class of inhibitors of herpes simplex virus replication was found. The compounds under study are derived from condensed 1,2,4-triazolo[5,1-c][1,2,4]triazines and 1,2,4-triazolo[1,5-a]pyrimidines, structural analogues of natural nucleic bases. A
Autor:
S. L. Deev, T. S. Shestakova, Oleg I. Kiselev, Rusinova Larisa I, E. G Deeva, O. N. Chupakhin, E. N. Ulomskii, Vladimir L. Rusinov
Publikováno v:
Russian Chemical Bulletin. 59:136-143
Nucleoside analogs containing hydroxybutyl, hydroxyethoxymethyl, allyloxymethyl, and propargyloxymethyl fragments were synthesized based on 1,2,4-triazolo[3,2-c][1,2,4]triazin-7-ones isosteric to purine bases. Some of the compounds obtained inhibit i
Autor:
V. I. Saloutin, M. V. Pryadeina, Ya. V. Burgart, E. N. Ulomskii, Pavel A. Slepukhin, E. V. Sadchikova
Publikováno v:
Russian Journal of Organic Chemistry. 45:242-247
Methods were developed of the synthesis of alkyl 2-hydroxy-2-fluoroalkyl-4-phenyl-1,2,3,4—tetrahydroimidazo-[1,5-a]pyrimidine-3-carboxylates and alkyl-5-hydroxy-2,7-diphenyl-5-fluoroalkyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-6-carboxylates b
Publikováno v:
Russian Chemical Bulletin. 57:985-1014
Synthetic methods, reactivity, and the properties of a new class of antiviral compounds, pyrazolo-, imidazo-, 1,2,4-triazolo[5,1-c]-1,2,4-triazinones, tetrazolo[5,1-b]-1,2,4-triazinones, and azoloannulated amino-1,2,4-triazines having structural simi
Autor:
Maksim L. Isenov, Gennady L. Rusinov, Valery N. Charushin, E. N. Ulomskii, Evgeny B. Gorbunov
Publikováno v:
ChemInform. 46
Title compounds are conveniently and in high yields synthesized by a regioselective reaction from 6-nitroazolo[1,5-a]pyrimidines with sodium azide.
Publikováno v:
Russian Chemical Bulletin. 54:726-732
A new in principle method for the synthesis of 6-aryl(hetaryl)-3,5-diamino-1,2,4-triazines by decomposition of pre-synthesized tetrazolo[1,5-b][1,2,4]triazines was developed. The advantages of this method over traditional methods were demonstrated us
Autor:
V. I. Saloutin, M. I. Kodess, Ya. V. Burgart, E. N. Ulomskii, M. V. Pryadeina, Vladimir L. Rusinov
Publikováno v:
Russian Journal of Organic Chemistry. 40:902-907
Fluorinated 3-oxo esters react with aldehydes and 3-amino-1,2,4-triazoles and 5-aminotetrazoles to give, respectively, 7-alkyl(aryl)-6-alkoxycarbonyl-5-fluoroalkyl-1,2,4-triazolo[1,5-a]pyrimidines and -tetra-zolo[1,5-a]pyrimidines. The same heterocyc