Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E. N. Nabirochkina"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 2, Pp 174-179 (2019)
SAGA/TFTC, which is a histone acetyltransferase complex, plays an important role in the regulation of transcription. We have identified that the metazoan TFTC/STAGA complexes had histone H2A and H2B deubiquitinase activity that is carried out by a DU
Externí odkaz:
https://doaj.org/article/f2406e2493774e13a275af31fe56d00d
Autor:
J. V. Nikolenko, Y. A. Vdovina, E. I. Fefelova, A. A. Glukhova, E. N. Nabirochkina, D. V. Kopytova
Publikováno v:
Molecular Biology. 55:432-440
Publikováno v:
RNA Biol
The TREX-2 complex is essential for the general nuclear mRNA export in eukaryotes. TREX-2 interacts with the nuclear pore and transcriptional apparatus and links transcription to the mRNA export. However, it remains poorly understood how the TREX-2-d
Publikováno v:
Molekuliarnaia biologiia. 55(3)
SAGA, the multicomponent complex responsible for acetylation of histone N-terminal lysine residues, is involved in the transcription activation of a wide range of eukaryote genes. SAGA contains a protein module, DUB, which is responsible for histone
Publikováno v:
Molekuliarnaia biologiia. 47(6)
SAGA is a histone acetyltransferase complex, that cotranscriptionally performs histone modifications and is implicated in regulation of gene expression at the level of changes in chromatin structure. SAGA is also involved in mRNP biogenesis and expor
Publikováno v:
Molekuliarnaia biologiia. 47(6)
Eukaryotic gene expression is known as a multistep process of high complexity. Transcription is one of cardinal and tightly regulated phase during gene expression. To provide accurate and precise work of gene regulation apparatus including a plethora
Autor:
A V, Shaposhnikov, A S, Kryndushkin, Iu V, Nikolenko, V V, Panov, E N, Nabirochkina, L A, Lebedeva, Iu V, Shidlovskiĭ
Publikováno v:
Molekuliarnaia biologiia. 47(3)
JAK/STAT signaling pathway plays a critical role in different ontogenesis processes of higher eukaryotes. Fruit fly drosophila is a handy model system used to study this pathway since major components of the pathway are represented by unique factors.
Autor:
N E, Vorob'eva, Iu V, Nikolenko, A N, Krasnov, Iu L, Kuz'mina, V V, Panov, E N, Nabirochkina, S G, Georgieva, Iu V, Shidlovskiĭ
Publikováno v:
Genetika. 48(1)
The role of metazoan coactivator SAYP in nuclear receptor-driven gene activation in the ecdysone cascade of Drosophila is considered. SAYP interacts with DHR3 nuclear receptor and activates the corresponding genes by recruiting the BTFly (Brahma and
Autor:
D Ia, Gurskiĭ, A V, Orlova, D V, Kopytova, A N, Krasnov, E N, Nabirochkina, S G, Georgieva, Iu V, Shidlovskiĭ
Publikováno v:
Genetika. 46(12)
The ENY2/Sus1 is a multifunctional transcription factor which couples transcription with mRNA export. It is the component of the SAGA/TFTC and TREX-2/AMEX protein complexes. Recently, we described the interaction of ENY2 with one more protein complex
Autor:
N E, Vorob'eva, N V, Soshnikova, Iu V, Nikolenko, Iu L, Kuz'mina, E N, Nabirochkina, S G, Georgieva, Iu V, Shidlovskiĭ
Publikováno v:
Molekuliarnaia biologiia. 44(5)
In the S2 cell system of Drosophila melanogaster a key protein domain mediating the interaction of TFIID and Brahma transcriptional complexes into the BTFly supercomplex has been shown to be an evolutionary conserved SAY domain of the SAYP. TFIID and