Zobrazeno 1 - 10
of 27
pro vyhledávání: '"E. N. Fish"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 2, Pp 171-180 (2024)
Introduction. The number of peptide drugs being developed and registered has increased in recent years. Therefore, modern analytical approaches and methods are required to determine these substances in biological matrices during pharmacokinetic studi
Externí odkaz:
https://doaj.org/article/ca229898dcb64eb98ed226927dc02bf9
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 14, Iss 1, Pp 42-52 (2024)
SCIENTIFIC RELEVANCE. Biowaiver is a procedure for establishing the bioequivalence of generic and reference products without in vivo studies. Regulatory requirements for this procedure, as described in a variety of documents, differ in certain featur
Externí odkaz:
https://doaj.org/article/82ae18b02df645fb9464495a3d62b9a7
Autor:
A. M. Poluyanov, A. Kochug, L. S. Mitrofanova, I. D. Nikitin, O. Yu. Vergasov, I. E. Shohin, E. N. Fisher
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 2, Pp 62-72 (2023)
Introduction. Taurine is a non-proteinogenic amino acid. The molecule is involved in lipid metabolism, adsorbs fat-soluble vitamins, and its conjugates with bile acids contribute to the emulsification of fats in the intestine. Drugs, which include a
Externí odkaz:
https://doaj.org/article/a5904b31952b43d09088d9f99f58ab2b
Publikováno v:
Applied Clinical Informatics. :472-482
SummaryBackground: Clinical trials are widely accepted as a necessary step in evaluating the safety and efficacy of new pharmaceutical products. In order for a sufficiently powered study, a clinical trial depends on the effective and unbiased recruit
Autor:
D. Kashiwakuma, H. Sanjo, I. Ho, S. Tsai, S. Teh, M. Niu, Rachel Kelly Beach, O. Usami, A. T. Ting, S. Andersson, M. Liu, Y. Yamashita, O. Ikeda, S. Lin, Y. Amano, T. Onoda, M. Grusby, E. Raducan, R. Stanculescu, H. Teh, M. Obata, N. Khorana, L. Wang, X. Guo, M. C. Letellier, Y. Jacques, M. Rahman, T. Kasahara, L. Lu, J. Vakkila, K. Hirose, T. Matsuda, J. Wauman, P. Kim, H. Hase, H. Li, Y. Wang, H. Nara, T. Naka, H. Seong, M. Tsubouchi, Y. Kuninaka, G. Seo, E. Codorean, R. Lissilaa, A. J. Tormo, M. Bokarewa, M. Mihara, Y. Tomita, N. Mukaida, George N. Pavlakis, Z. Liu, Q. L. Lam, H. Tsao, D. Sykes, S. Kamitani, S. R. McColl, M. Dehlin, T. Nishikawa, L. Forfang, S. G. Tangye, N. Tanaka, M. Hashizume, N. Tsuyama, Y. Hiramatsu, P. Jeannin, Antonio Valentin, A. Suto, Cristina Bergamaschi, N. Watanabe, S. Crabé, T. T. Murooka, K. Shimoda, S. Nakazawa, C. N. Tanase, S. L. Reynolds, Brunda Ganneru, K. Satoh, A. Araki, H. Nakajima, A. Kimura, S. Miaw, M. Abe, V. I. Hilden, K. Yoshino, E. B. Smeland, W. Ferlin, S. Kagami, K. Sugiura, K. Ikeda, S. Mustjoki, S. Kawakami, U. Magoungou-Bigouagou, J. Kamishimoto, M. S. Iqbal, H. Yoshida, M. Nakajima, K. Oritani, S. Lievens, A. Hellvard, T. Kobata, E. N. Benveniste, T. Imaizumi, M. Erlandsson, D. Ma, J. Reynolds, I. Iwamoto, V. Solé, R. Manoharan, Y. Ishida, H. Fujii, H. Ishikawa, R. Muromoto, G. Bouchaud, S. Jalkanen, Y. Sekine, M. Brisslert, K. Tago, E. Mortier, N. Bethge, A. Domaszewska-Szostek, J. Kim, T. Li, S. Mahajan, T. Kondo, Y. Muro, S. Chuchawankul, Y. Méliani, W. Olszewski, R. Grenningloh, B. Lin, J. Tavernier, W. Han, A. Manjang, Y. Twu, G. Elson, H. Qin, H. Lee, D. Duluc, M. Zaleska, J. H. Myklebust, R. Albulescu, M. Suzuki, S. Togi, P. Tsai, S. A. Schwartz, L. De Ceuninck, X. Ma, N. Moheghi, M. P. Oksvold, M. Shiina, T. Matsumiya, I. D. Popescu, M. Funakoshi-Tago, C. Lin, M. Yamaki, K. Porkka, X. Cui, H. Perdreau, C. F. Ware, A. Plet, C. Akekawatchai, R. Aalinkeel, F. M. Juliana, G. Zhang, K. Yoshizaki, J. F. Gauchat, J. C. Wallace, H. Asao, B. J. Baker, E. N. Fish, C. Tsai, L. Albulescu, W. Hsieh, O. Chan, K. Kojima, H. Ha, T. Takeshita, K. Chadha
Publikováno v:
International Immunology. 22:ii138-ii145
Autor:
I. A. Pozharnov, A. S. Simakov, N. A. Shulga, A. Yu. Savchenko, O. I. Perederyaev, L. S. Synkova, Yu. V. Medvedev, E. N. Fisher
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 2, Pp 153-158 (2022)
Introduction. Hygienic monitoring of air pollution at the pharmaceutical enterprise required by the law of the Russian Federation (orders, standards, methodological guidelines and guidelines). This requirement follows from the need to protect the per
Externí odkaz:
https://doaj.org/article/5397b2835c6540e3bf3a39e2f88033cd
Publikováno v:
Allergy. 69(7)
Background The inflammatory immune response associated with allergic airway inflammation in asthma involves T helper type 2 (Th2) immunity. Given the data that a newly described late activator antigen-presenting cell (LAPC) population promotes Th2 im
Autor:
V. G. Nesterenko, R. N. Bolgarin, B. A. Rudoy, D. K. Salakhetdinov, Yu. G. Kazaishvili, V. S. Scherbakova, N. A. Nikitina, Yu. V. Medvedev, E. N. Fisher, E. A. Malashenko, I. E. Shohin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 3, Pp 55-69 (2021)
Introduction. Due to increase in the frequency of detecting cases of tuberculosis caused by strains of mycobacteria with resistance not only to traditional, but also recently introduced into clinical circulation anti-tuberculosis drugs, it is urgent
Externí odkaz:
https://doaj.org/article/1077dff211704e05b2bc1083b9eb0534
Publikováno v:
The Journal of Immunology. 158:2390-2397
During engagement of the type I IFN receptor, IRS-1 is phosphorylated on tyrosine and associates with the p85 regulatory subunit of the phosphatidylinositol (PI) 3'-kinase, which is a dual-specificity enzyme possessing both lipid and serine kinase ac
Autor:
Yu. V. Medvedev, M. A. Kolganova, O. A. Sas, T. N. Komarov, E. N. Fisher, I. E. Shohin, Yu. I. Ammour
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 9, Iss 2, Pp 140-144 (2020)
Introduction. Neutropenia, which is an abnormally low concentration of neutrophils in the blood, is one of the common side effects in patients receiving radio- or chemotherapy. Neutropenia usually leads to higher risks of severe bacterial and fungal
Externí odkaz:
https://doaj.org/article/b0e3df8c29cb4260ba757cb13bbddecf