Modulation of genetic associations with serum urate levels by body-mass-index in humans.

Autor: Jennifer E Huffman, Eva Albrecht, Alexander Teumer, Massimo Mangino, Karen Kapur, Toby Johnson, Zoltán Kutalik, Nicola Pirastu, Giorgio Pistis, Lorna M Lopez, Toomas Haller, Perttu Salo, Anuj Goel, Man Li, Toshiko Tanaka, Abbas Dehghan, Daniela Ruggiero, Giovanni Malerba, Albert V Smith, Ilja M Nolte, Laura Portas, Amanda Phipps-Green, Lora Boteva, Pau Navarro, Asa Johansson, Andrew A Hicks, Ozren Polasek, Tõnu Esko, John F Peden, Sarah E Harris, Federico Murgia, Sarah H Wild, Albert Tenesa, Adrienne Tin, Evelin Mihailov, Anne Grotevendt, Gauti K Gislason, Josef Coresh, Pio D'Adamo, Sheila Ulivi, Peter Vollenweider, Gerard Waeber, Susan Campbell, Ivana Kolcic, Krista Fisher, Margus Viigimaa, Jeffrey E Metter, Corrado Masciullo, Elisabetta Trabetti, Cristina Bombieri, Rossella Sorice, Angela Döring, Eva Reischl, Konstantin Strauch, Albert Hofman, Andre G Uitterlinden, Melanie Waldenberger, H-Erich Wichmann, Gail Davies, Alan J Gow, Nicola Dalbeth, Lisa Stamp, Johannes H Smit, Mirna Kirin, Ramaiah Nagaraja, Matthias Nauck, Claudia Schurmann, Kathrin Budde, Susan M Farrington, Evropi Theodoratou, Antti Jula, Veikko Salomaa, Cinzia Sala, Christian Hengstenberg, Michel Burnier, Reedik Mägi, Norman Klopp, Stefan Kloiber, Sabine Schipf, Samuli Ripatti, Stefano Cabras, Nicole Soranzo, Georg Homuth, Teresa Nutile, Patricia B Munroe, Nicholas Hastie, Harry Campbell, Igor Rudan, Claudia Cabrera, Chris Haley, Oscar H Franco, Tony R Merriman, Vilmundur Gudnason, Mario Pirastu, Brenda W Penninx, Harold Snieder, Andres Metspalu, Marina Ciullo, Peter P Pramstaller, Cornelia M van Duijn, Luigi Ferrucci, Giovanni Gambaro, Ian J Deary, Malcolm G Dunlop, James F Wilson, Paolo Gasparini, Ulf Gyllensten, Tim D Spector, Alan F Wright, Caroline Hayward, Hugh Watkins, Markus Perola, Murielle Bochud, W H Linda Kao, Mark Caulfield, Daniela Toniolo, Henry Völzke, Christian Gieger, Anna Köttgen, Veronique Vitart

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119752 (2015)

We tested for interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, in up to 42569 participants. Both stratified genome-wide association (GWAS) analyses, in lean, overweight and obese indivi

Externí odkaz: https://doaj.org/article/adaf5b3ebb05477891a1b783a439bd5e

Prognostication via early computed tomography head in patients treated with targeted temperature management after cardiac arrest

Autor: Jason J. Chang, Marc D. Malkoff, Dipen Kadaria, Andrei Yankovich, Georgios Tsivgoulis, Srishti Sareen, Amik Sodhi, Lucas Elijovich, Khalid Alsherbini, Jeffrey E. Metter, Luis C. Murillo, Craig Schuring, Rabin Shrestha, Nitin Goyal, Andrei V. Alexandrov

Publikováno v: Journal of the neurological sciences. 406

Background We evaluated computed tomography head (CTH) imaging obtained prior to targeted temperature management (TTM) in patients after cardiac arrest, and its role in prognostication. Methods In this retrospective cohort study in a tertiary-care ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fe99c7536f4367aef65add13f9481e
https://pubmed.ncbi.nlm.nih.gov/31521958

Abstract 166: Supervised Learning Based Detection of Stroke and Stroke Mimic

Autor: Vida Abedi, Nitin Goyal, Niyousha Hosseinichimeh, Georgios Tsivgoulis, Raquel Hontecillas, Josep Bassaganya-Riera, Pinyi Lu, Jason Chang, Navid Ghaffarzadegan, Lucas Elijovich, Jeffrey E Metter, Anne W Alexandrov, David S Liebeskind, Andrei Alexandrov, Ramin Zand

Publikováno v: Stroke. 47

Background & Purpose: Up to 30% of treated patients for suspected acute ischemic stroke (AIS) could be stroke mimic (SM). Using a balanced clinical dataset, we have developed a supervised learning method from artificial intelligence to classify AIS/t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bbbdf93c1598cac3bd09582ec3be62a
https://doi.org/10.1161/str.47.suppl_1.166

Effect of strength training on resting metabolic rate and physical activity: age and gender comparisons

Autor: Alice S. Ryan, Jeffrey E. Metter, James L. Fozard, Frederick M. Ivey, Jeffrey T. Lemmer, Jerome L. Fleg, Ben F. Hurley, Greg F. Martel, D. E. Hurlbut

Publikováno v: Medicine and science in sports and exercise. 33(4)

The purpose of this study was to compare age and gender effects of strength training (ST) on resting metabolic rate (RMR), energy expenditure of physical activity (EEPA), and body composition.RMR and EEPA were measured before and after 24 wk of ST in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdef6c978ffc07ee76fd3f9f7f0b7103
https://pubmed.ncbi.nlm.nih.gov/11283427

What should be the morphologic criteria for the subdivision of follicular lymphomas?

Autor: B N, Nathwani, G E, Metter, T P, Miller, J S, Burke, R B, Mann, M, Barcos, C R, Kjeldsberg, D O, Dixon, C D, Winberg, C C, Whitcomb

Publikováno v: Blood. 68:837-845

The members of the Pathology Panel for Lymphoma Clinical Studies undertook a collaborative study with the hope of resolving some of the controversies regarding the criteria and methods for the subclassification of follicular lymphomas (FLs). A group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4b8dc9c8669b2d01ca5a08f4a9e576
https://doi.org/10.1182/blood.v68.4.837.bloodjournal684837