Zobrazeno 1 - 10
of 2 882
pro vyhledávání: '"E. McCloskey"'
Autor:
Yanping Yang, Huan Yang, Yago Alcaina, Janusz Puc, Alyssa Birt, Yogindra Vedvyas, Michael Gallagher, Srinija Alla, Maria Cristina Riascos, Jaclyn E. McCloskey, Karrie Du, Juan Gonzalez-Valdivieso, Irene M. Min, Elisa de Stanchina, Matt Britz, Eric von Hofe, Moonsoo M. Jin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The limited number of targetable tumor-specific antigens and the immunosuppressive nature of the microenvironment within solid malignancies represent major barriers to the success of chimeric antigen receptor (CAR)-T cell therapies. Here, us
Externí odkaz:
https://doaj.org/article/1773c1a113ad431dbfb194f4da0fc107
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The ability to image adoptively transferred T cells in the body and to eliminate them to avoid toxicity will be vital for chimeric antigen receptor (CAR) T cell therapy, particularly against solid tumors with higher risk of off-tumor toxicit
Externí odkaz:
https://doaj.org/article/b4d931c057124558b1311f10901b0857
Autor:
Ryan Brisbin, Mark Bartolo, Michael Leville, Arya K. Rajan, Basharat Jahan, Kara E. McCloskey, Ajay Gopinathan, Sayantani Ghosh, Ryan Baxter
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract We investigate the effect of bis(imino)pyridine (BIP) ligands in guiding self-assembly of semiconducting CdSe/ZnS quantum dots (QDs) into three-dimensional multi-layered shells with diameters spanning the entire mesoscopic range, from 200 nm
Externí odkaz:
https://doaj.org/article/5a84d3b1a4f44c1491905b5a1b812aad
Autor:
Shiwani Limbu, Kara E McCloskey
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294171 (2023)
Lung cancer makes up one-fourth of all cancer-related mortality with the highest mortality rate among all cancers. Despite recent scientific advancements in cancer therapeutics, the 5-year survival rate of lung adenocarcinoma (LUAD) cancer patients r
Externí odkaz:
https://doaj.org/article/28367b54529d47c18d73f97cd2598d29
Autor:
Willner, Don S.
Publikováno v:
Oregon Historical Quarterly, 1972 Sep 01. 73(3), 275-276.
Externí odkaz:
https://www.jstor.org/stable/20613312
Autor:
Minkyu Jung, Yanping Yang, Jaclyn E. McCloskey, Marjan Zaman, Yogindra Vedvyas, Xianglan Zhang, Dessislava Stefanova, Katherine D. Gray, Irene M. Min, Raza Zarnegar, Yoon Young Choi, Jae-Ho Cheong, Sung Hoon Noh, Sun Young Rha, Hyun Cheol Chung, Moonsoo M. Jin
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 587-601 (2020)
Cancer therapy utilizing adoptive transfer of chimeric antigen receptor (CAR) T cells has demonstrated remarkable clinical outcomes in hematologic malignancies. However, CAR T cell application to solid tumors has had limited success, partly due to th
Externí odkaz:
https://doaj.org/article/2d219804286b4b9eabd7428add107045
Autor:
Basharat Jahan, Kara E. McCloskey
Publikováno v:
Stem Cell Research, Vol 42, Iss , Pp - (2020)
Human endothelial cells (ECs) are important tools in research and development of new therapies in the fields of angiogenesis, vasculogenesis, engineering organoids and multicellular tissues, drug discovery, and disease modeling. Efficient and robust
Externí odkaz:
https://doaj.org/article/3728242e392240b5a12f918d629b049d
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background Vascular progenitor cells (VPCs) derived from embryonic stem cells (ESCs) are a valuable source for cell- and tissue-based therapeutic strategies. During the optimization of endothelial cell (EC) inductions from mouse ESCs using o
Externí odkaz:
https://doaj.org/article/f349aa99471e4090bb4e46cd16334275
Autor:
Moonsoo M. Jin, Eric von Hofe, Irene M. Min, Elisa de Stanchina, Elizabeth Ortiz-Sánchez, Angel A. Gomez Gallegos, Yogindra Vedvyas, Yago Alcaina, Janusz Puc, Huan Yang, Jaclyn E. McCloskey, Yanping Yang
Supplementary figure S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dfdb9e9b827e7f29066eba501eb4c2
https://doi.org/10.1158/2326-6066.22543752
https://doi.org/10.1158/2326-6066.22543752
Autor:
Moonsoo M. Jin, Eric von Hofe, Irene M. Min, Elisa de Stanchina, Elizabeth Ortiz-Sánchez, Angel A. Gomez Gallegos, Yogindra Vedvyas, Yago Alcaina, Janusz Puc, Huan Yang, Jaclyn E. McCloskey, Yanping Yang
Adoptive transfer of chimeric antigen receptor (CAR) T cells has demonstrated unparalleled responses in hematologic cancers, yet antigen escape and tumor relapse occur frequently. CAR T-cell therapy for patients with solid tumors faces even greater c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34596a68357300f1ed8c25f75b8631de
https://doi.org/10.1158/2326-6066.c.6550395.v1
https://doi.org/10.1158/2326-6066.c.6550395.v1