Zobrazeno 1 - 10
of 772
pro vyhledávání: '"E. McCall"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Skeletal muscle hypertrophy is generally associated with a fast-to-slow phenotypic adaptation in both human and rodent models. Paradoxically, this phenotypic shift is not paralleled by a concomitant increase in mitochondrial content and aerobic marke
Externí odkaz:
https://doaj.org/article/8b2f298f8b5f4e10b6c146b292250ffa
Autor:
Ella M. Samuel, Jennifer K. Meineke, Laine E. McCall, Lea B. Selby, Alison C. Foster, Zoe M. Davidson, Carol A. Dawson, Catherine S. Jarnevich, Sarah K. Carter
Publikováno v:
Conservation Science and Practice, Vol 6, Iss 6, Pp n/a-n/a (2024)
Abstract Public lands are often managed for multiple uses ranging from energy development to rare plant conservation. Habitat models can help land managers assess and mitigate potential effects of projects on rare plants, but it is unclear how models
Externí odkaz:
https://doaj.org/article/870569ff2b504b149c6ddc34d23afdf7
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102841- (2023)
Lipopolysaccharide (LPS) is a known inducer of inflammatory signaling which triggers generation of reactive oxygen species (ROS) and cell death in responsive cells like THP-1 promonocytes and freshly isolated human monocytes. A key LPS-responsive met
Externí odkaz:
https://doaj.org/article/3f8315755fd84d899189a7b058cb3110
Autor:
Allison K. Meyers, Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan, Juan Liu, Qianyi Zhang, Rajesh K. Manne, Felipe Lorenzo, Matthew A. Quinn, Qianqian Song, Daping Fan, Hui-Kuan Lin, Cristina M. Furdui, Jason W. Locasale, Charles E. McCall, Xuewei Zhu
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111941- (2023)
Summary: Activating the macrophage NLRP3 inflammasome can promote excessive inflammation with severe cell and tissue damage and organ dysfunction. Here, we show that pharmacological or genetic inhibition of pyruvate dehydrogenase kinase (PDHK) signif
Externí odkaz:
https://doaj.org/article/9e44575ee34a4202a7a3e462e4561170
Publikováno v:
Journal of Innate Immunity, Pp 1-12 (2021)
Sepsis-induced myeloid-derived suppressor cells (MDSCs) increase mortality risk. We previously identified that long non-coding RNA Hotairm1 supports myeloid precursor shifts to Gr1+CD11b+ MDSCs during mouse sepsis. A major unanswered question is what
Externí odkaz:
https://doaj.org/article/e05f50ddef4a4addaaec5261642bf9f1
Autor:
Tae Seok Oh, Manal Zabalawi, Shalini Jain, David Long, Peter W. Stacpoole, Charles E. McCall, Matthew A. Quinn
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection. The metabolic aberrations associated with sepsis underly an acute and organism-wide hyperinflammatory response and multiple organ dysfunction; howeve
Externí odkaz:
https://doaj.org/article/5d981fcaf4444ba598df155e5fb19c2a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/93b47db0ab19473eb07a8d3237ca4c07
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Myeloid-derived suppressor cells (MDSCs) prolong sepsis by promoting immunosuppression. We reported that sepsis MDSC development requires long non-coding RNA Hotairm1 interactions with S100A9. Using a mouse model that simulates the immunobiology of s
Externí odkaz:
https://doaj.org/article/a392f19a3324495d81ecb915b3b4ed51
Autor:
L Madison Kirk, Charlotte Mae K Waits, Alexander C Bashore, Beverly Dosso, Allison K Meyers, Antonio C Renaldo, Thomas J DePalma, Kelli N Simms, Nathaniel Hauser, Chia-Chi Chuang Key, Charles E McCall, John S Parks, Susan Sergeant, Carl D Langefeld, Aleksander Skardal, Elaheh Rahbar
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262173 (2022)
The Modern Western Diet has been associated with the rise in metabolic and inflammatory diseases, including obesity, diabetes, and cardiovascular disease. This has been attributed, in part, to the increase in dietary omega-6 polyunsaturated fatty aci
Externí odkaz:
https://doaj.org/article/f2c6eac11b404b5b9fab58864eb69f57
Autor:
Qingxia Zhao, Zhan Wang, Allison K. Meyers, Jennifer Madenspacher, Manal Zabalawi, Qianyi Zhang, Elena Boudyguina, Fang-Chi Hsu, Charles E. McCall, Cristina M. Furdui, John S. Parks, Michael B. Fessler, Xuewei Zhu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Macrophages play a central role in the pathogenesis of atherosclerosis. Our previous study demonstrated that solute carrier family 37 member 2 (SLC37A2), an endoplasmic reticulum-anchored phosphate-linked glucose-6-phosphate transporter, negatively r
Externí odkaz:
https://doaj.org/article/faf5fd19e0c94aa199d2c274dfbde07e