Zobrazeno 1 - 10 of 34 pro vyhledávání: '"E. M. Southern"'
2
Ellipsometric and Interferometric Characterization of DNA Probes Immobilized on a Combinatorial Array
Autor: S. C. Case-Green, D. E. Gray, E. M. Southern, P. J. Dobson, T. S. Fell
Publikováno v: Langmuir. 13:2833-2842
We have used ellipsometry to study oligonucleotides bound on an array by observing changes in the optical thickness of the organic material attached to the surface. Interferometry has been used as a complementary technique to confirm our ellipsometry
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f25ca16e40030d5a6e4dea51f6e25296
https://doi.org/10.1021/la962139m
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3
DNA fingerprinting by hybridisation to oligonucleotide arrays
Autor: E. M. Southern
Publikováno v: Electrophoresis. 16:1539-1542
Most methods for analysing variation in DNA sequences rely on gel electrophoresis, a method which is difficult to automate and to quantify. Hybridisation to oligonucleotides bound to a solid surface offers alternatives, with the advantage that they c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95b65ca50b7f44cd41f6f1503f301ae
https://doi.org/10.1002/elps.11501601256
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4
Oligonucleotide scanning arrays: application to high-throughput screening for effective antisense reagents and the study of nucleic acid interactions
Autor: M, Sohail, E M, Southern
Publikováno v: Advances in biochemical engineering/biotechnology. 77
Oligonudeotide scanning arrays are useful tools in the study of nucleic acid interaction. Such arrays of oligonucleotides, corresponding to a full set of complements of a known sequence, can be readily made in a single series of coupling reactions, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::668c242c4eaf26b4f2f89d03ff7afe1f
https://pubmed.ncbi.nlm.nih.gov/12227736
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7
Hybridization of antisense reagents to RNA
Autor: M, Sohail, E M, Southern
Publikováno v: Current opinion in molecular therapeutics. 2(3)
Despite the simplicity of the concept, almost every step in an antisense experiment poses difficulties. Finding a site that is accessible to intermolecular hybridization with complementary nucleic acids is a major problem and determines the success o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a19f8cd0ef3c41f8013bd005ab773a0d
https://pubmed.ncbi.nlm.nih.gov/11249620
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8
DNA Variation and Its Analysis by Hybridisation to Oligonucleotide Arrays
Autor: E. M. Southern
Publikováno v: Advances in Forensic Haemogenetics ISBN: 9783540576433
DNA analysis is now widely used in medical and forensic science. As an indicator for the presence of an infectious agent, as a means of detecting mutation associated with an inherited disease gene, or as an individual fingerprint, DNA analysis surpas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4089e2c6a516adfab23923d0b9838d9
https://doi.org/10.1007/978-3-642-78782-9_19
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