Zobrazeno 1 - 10
of 31
pro vyhledávání: '"E. M. Saeed"'
Publikováno v:
ACS Omega, Vol 5, Iss 30, Pp 18662-18674 (2020)
Externí odkaz:
https://doaj.org/article/3715a1a075944b64920ea3c0a69f24b3
Publikováno v:
International Journal of Analysis and Applications, Vol 20, Pp 53-53 (2022)
In this paper, a mathematical model of hepatitis B virus with vaccination and treatments is studied, Stability analysis discussed and the disease-free equilibrium and endemic equilibrium points obtained, the basic reproductive number R0 determined an
Externí odkaz:
https://doaj.org/article/f72d83f2500c4fc1b108f749a8cc8811
Autor:
Mohamed E. M. Saeed, Rümeysa Yücer, Mona Dawood, Mohamed-Elamir F. Hegazy, Assia Drif, Edna Ooko, Onat Kadioglu, Ean-Jeong Seo, Fadhil S. Kamounah, Salam J. Titinchi, Beatrice Bachmeier, Thomas Efferth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3966 (2022)
The improvement of cancer chemotherapy remains a major challenge, and thus new drugs are urgently required to develop new treatment regimes. Curcumin, a polyphenolic antioxidant derived from the rhizome of turmeric (Curcuma longa L.), has undergone e
Externí odkaz:
https://doaj.org/article/66f69f61e67b475180bbaa830d1dd633
Autor:
Onat Kadioglu, Mohamed E M Saeed, Markus Munder, Andreas Spuller, Henry Johannes Greten, Thomas Efferth
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss , Pp 110718- (2020)
ATP-binding cassette (ABC) transporters mediate multidrug resistance in cancer. In contrast to DNA single nucleotide polymorphisms in normal tissues, the role of mutations in tumors is unknown. Furthermore, the significance of their expression for pr
Externí odkaz:
https://doaj.org/article/eb35e82d742a4a19808300b31c269eaf
Autor:
Joelle C. Boulos, Mohamed E. M. Saeed, Manik Chatterjee, Yagmur Bülbül, Francesco Crudo, Doris Marko, Markus Munder, Sabine M. Klauck, Thomas Efferth
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1126 (2021)
Crizotinib was a first generation of ALK tyrosine kinase inhibitor approved for the treatment of ALK-positive non-small-cell lung carcinoma (NSCLC) patients. COMPARE and cluster analyses of transcriptomic data of the NCI cell line panel indicated tha
Externí odkaz:
https://doaj.org/article/0287c6085c9e4590b630f9d66419fce4
Autor:
Leander Geske, Ulrich Kauhl, Mohamed E. M. Saeed, Anja Schüffler, Eckhard Thines, Thomas Efferth, Till Opatz
Publikováno v:
Molecules, Vol 26, Iss 11, p 3224 (2021)
The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses. The total synthesis of shancigusin C (1) was conducted by employing the Perkin reaction
Externí odkaz:
https://doaj.org/article/ee3cff6e205f45be9168ced622b4541f
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Artemisinin and its derivatives are not only approved antimalarial drugs but also exert strong anticancer activity. Based on the clinical activity of artesunate (ART) that has been previously reported in cervix carcinoma, we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49565fd6a4795685f87354022cb9a11f
https://europepmc.org/articles/PMC9620444/
https://europepmc.org/articles/PMC9620444/
Autor:
Xiaohua Lu, Mohamed E. M. Saeed, Mohamed-Elamir F. Hegazy, Christopher J. Kampf, Thomas Efferth
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1000 (2020)
The popular beverage green tea possesses chemopreventive activity against various types of tumors. However, the effects of its chemopreventive effect on hematological malignancies have not been defined. In the present study, we evaluated antitumor ef
Externí odkaz:
https://doaj.org/article/722e8a3b97e44592ab3fd20e8a425986
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lin
Externí odkaz:
https://doaj.org/article/2e63aae3d82b4776903432f59075cc1c
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
For decades, natural products represented a significant source of diverse and unique bioactive lead compounds in drug discovery field. In Clinical oncology, complete tumors remission is hampered by the development of drug-resistance. Therefore, devel
Externí odkaz:
https://doaj.org/article/98153297744c480c8b26e1e2bf407cef