Zobrazeno 1 - 10
of 39
pro vyhledávání: '"E. M. Price"'
Autor:
A. Khan, A. M. Inkster, M. S. Peñaherrera, S. King, S. Kildea, T. F. Oberlander, D. M. Olson, C. Vaillancourt, U. Brain, E. O. Beraldo, A. G. Beristain, V. L. Clifton, G. F. Del Gobbo, W. L. Lam, G. A. S. Metz, J. W. Y. Ng, E. M. Price, J. M. Schuetz, V. Yuan, É. Portales-Casamar, W. P. Robinson
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina Infinium Methylation bead arrays is often used to explore the connections between in utero exposures, placental pathology, and fetal development. However,
Externí odkaz:
https://doaj.org/article/8b96f07395584eb49a0b50d3239d7f7e
Autor:
E. M. Price, Wendy P. Robinson
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
It is well-known, but frequently overlooked, that low- and high-throughput molecular data may contain batch effects, i.e., systematic technical variation. Confounding of experimental batches with the variable(s) of interest is especially concerning,
Externí odkaz:
https://doaj.org/article/7258ffe5820d433aa70db433243ddf70
Autor:
Colin J. D. Ross, Aisha Ghani, C. van Karnebeek, E. M. Price, Harold Siden, Britt I. Drögemöller, Wyeth W. Wasserman, Allison Matthews, Ingrid Blydt-Hansen, Maja Tarailo-Graovac, Wendy P. Robinson
Publikováno v:
European journal of medical genetics, 60(10), 548-552. Elsevier Masson SAS
Here we report a 12 year old male with an extreme presentation of spastic paraplegia along with autism and dysmorphisms. Whole exome sequencing identified a predicted pathogenic pair of missense variants in SPAST at the same chromosomal location, eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f69f4e0420ca6a75c7143e9bbcf8ea1
https://doi.org/10.1016/j.ejmg.2017.07.015
https://doi.org/10.1016/j.ejmg.2017.07.015
Autor:
E. M. Price, Wendy P. Robinson
Publikováno v:
Cold Spring Harbor perspectives in medicine. 5(5)
This review provides an overview of the unique features of DNA methylation in the human placenta. We discuss the importance of understanding placental development, structure, and function in the interpretation of DNA methylation data. Examples are gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed13711a2ffc579966f706c8b543433
https://pubmed.ncbi.nlm.nih.gov/25722473
https://pubmed.ncbi.nlm.nih.gov/25722473
Publikováno v:
Journal of Endocrinology. 185:111-119
Thyroid disease has profound effects on cardiovascular function. Hypo- and hyperthyroidism, for example, are associated with reduced and increased maximal endothelium-dependent vasodilation respectively. We therefore hypothesized that the capacity fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee9340c68e9464c6173e3aadbc65976
https://doi.org/10.1677/joe.1.06022
https://doi.org/10.1677/joe.1.06022
Publikováno v:
The Journal of General Physiology
The endogenous Cl- conductance of Spodoptera frugiperda (Sf9) cells was studied 20-35 h after plating out of either uninfected cells or cells infected by a baculovirus vector carrying the cloned beta-galactosidase gene (beta-Gal cells). With the cati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53280de6d3f0e8ddd4ccf9e4e26388ad
https://doi.org/10.1085/jgp.107.6.695
https://doi.org/10.1085/jgp.107.6.695
Publikováno v:
Clinical pharmacology and therapeutics. 92(6)
Drug, hormonal, and nutritional exposures in pregnancy can cause birth defects, or have more subtle influences that may affect adult health through epigenetic developmental programming. Characterizing these epigenetic changes may provide valuable ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a758c3792d95b08fe69fec12bac7b9f
https://pubmed.ncbi.nlm.nih.gov/23047650
https://pubmed.ncbi.nlm.nih.gov/23047650
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(1)
Cystic fibrosis (CF) is an autosomal genetic disease associated with impaired epithelial ion transport. Mutations in the CF gene alter the primary sequence of the CF transmembrane conductance regulator (CFTR). Several therapeutic modalities have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d78d254a559a7c4e9fc970b963b4258
https://pubmed.ncbi.nlm.nih.gov/10991979
https://pubmed.ncbi.nlm.nih.gov/10991979
Publikováno v:
Cellular signalling. 7(7)
Differential regulation of PLC-beta 1 and -beta 2 by the G-protein alpha-subunit, G alpha 11, and by G-protein beta gamma-subunits was studied utilizing recombinant PLC-beta 1 and -beta 2. Rat PLC-beta 1 and human PLC-beta 2 were purified after recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66009aba4bba29a35a84224c860ab857
https://pubmed.ncbi.nlm.nih.gov/8519600
https://pubmed.ncbi.nlm.nih.gov/8519600
Publikováno v:
The Journal of biological chemistry. 269(12)
Cl- conductance of the apical membrane of airway epithelial cells has properties of a passive diffusion mechanism but is decreased by inhibition of oxidative metabolism. Recent reports that cAMP-dependent Cl- conductance also requires ATP at the intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3bcd9c1e6429c2f3caa506bb5d6d93d
https://pubmed.ncbi.nlm.nih.gov/7510695
https://pubmed.ncbi.nlm.nih.gov/7510695