Diagnostic strategy for the assessment of rheumatoid vasculitis

Autor: F J M van der Meer, F. C. Breedveld, J. M. W. Hazes, E M Paleolog, M. R. Daha, Alexandre E. Voskuyl, A. H. Zwinderman

Publikováno v: Annals of the Rheumatic Diseases, 62, 407-413. BMJ Publishing Group
Annals of the Rheumatic Diseases, 62(5), 407-13. BMJ Publishing Group
Voskuijl, A E, Hazes, JM, Zwinderman, A H, Paleolog, EM, van der Meer, FJ, Daha, MR & Breedveld, F C 2003, ' Diagnostic strategy for the assessment of rheumatoid vasculitis. ', Annals of the Rheumatic Diseases, vol. 62, no. 5, pp. 407-13 . https://doi.org/10.1136/ard.62.5.407
Annals of the rheumatic diseases, 62(5), 407-413. BMJ Publishing Group

Objective: To determine the clinical features associated with histologically proven rheumatoid vasculitis (HRV) and the additional diagnostic value of serological markers in an inception cohort of 81 patients with rheumatoid arthritis (RA) suspected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e62b5f3cd6ecb3a75c323f3edd1c47
https://doi.org/10.1136/ard.62.5.407

In vitro target validation and in vivo efficacy of p38 MAP kinase inhibition in established chronic collagen-induced arthritis model: a pre-clinical study

Autor: K, Triantaphyllopoulos, L, Madden, I, Rioja, D, Essex, J, Buckton, R, Malhotra, K, Ray, M, Binks, E M, Paleolog

Publikováno v: Clinical and experimental rheumatology. 28(2)

The aim of the present study was to determine the in vivo efficacy of p38 mitogen-activated protein kinase (MAPK) inhibitors, namely GW856553X and GSK678361, in murine models of arthritis.The effect of p38 MAPK inhibitors was tested in 2 variants of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b10bf92cfb1c3a032596265c0ece87a6
https://pubmed.ncbi.nlm.nih.gov/20406612

Angiogenesis in arthritis: role in disease pathogenesis and as a potential therapeutic target

Autor: E M, Paleolog, J M, Miotla

Publikováno v: Angiogenesis. 2(4)

Rheumatoid arthritis (RA) is a chronic destructive musculo-skeletal disorder, associated with thickening of the synovial membrane lining the joints, inflammation and hyperproliferation of synovial cells, as well as a pro-inflammatory cytokine cascade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::063d1ac4985ec08e969ce66b52a1fc07
https://pubmed.ncbi.nlm.nih.gov/14517450

Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis

Autor: S, Ballara, P C, Taylor, P, Reusch, D, Marmé, M, Feldmann, R N, Maini, E M, Paleolog

Publikováno v: Arthritis and rheumatism. 44(9)

To determine whether elevated levels of the angiogenic cytokine vascular endothelial growth factor (VEGF), detected on presentation to an early arthritis clinic, are associated with the development of chronic and erosive arthritis.Concentrations of V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1625304893bc707f94fc114f581ffce2
https://pubmed.ncbi.nlm.nih.gov/11592367

Vascular endothelial growth factor in normal human salivary glands and saliva: a possible role in the maintenance of mucosal homeostasis

Autor: N S, Taichman, A T, Cruchley, L M, Fletcher, E P, Hagi-Pavli, E M, Paleolog, W R, Abrams, V, Booth, R M, Edwards, D, Malamud

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 78(7)

Saliva is an enriched milieu containing biologically active proteins, including several different growth factors and cytokines. This study documents that vascular endothelial growth factor (VEGF), a potent, multifunctional, angiogenic cytokine, is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a9e4a422ffe75a0c1410806cf730350
https://pubmed.ncbi.nlm.nih.gov/9690564