Zobrazeno 1 - 10
of 12
pro vyhledávání: '"E. M. Delaey"'
Publikováno v:
Photochemistry and Photobiology. 74:331-338
Autor:
Peter de Witte, Bin Chen, Patrizia Agostinis, Tania Roskams, Jackie R. Vandenheede, Yan Xu, E. M. Delaey
Publikováno v:
International Journal of Cancer. 93:275-282
We investigated the hypericin-mediated PDT effects on the tumor and normal skin and in correlation with its biodistribution. These studies were carried out on C3H mice bearing RIF-1 tumors. The hypericin distribution and PDT effects were recorded at
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 56:19-24
The normoxic and hypoxic photocytotoxicity of hypericin has been examined on A431 cells as assessed by the Neutral Red method, using cell-culture flasks made of polystyrene and glass, different hypericin concentrations and light fluences. Using polys
Autor:
A. Vandenbogaerde, Bernard Himpens, E. M. Delaey, Wilfried Merlevede, Peter de Witte, Appolinary Kamuhabwa
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 45:87-94
Pseudohypericin and hypericin, the major photosensitizing constituents of Hypericum perforatum, are believed to cause hypericism. Since hypericin has been proposed as a photosensitizer for photodynamic cancer therapy, the photocytotoxicity of its con
Autor:
Peter de Witte, Annelies Vantieghem, Wilfried Merlevede, E. M. Delaey, A. Vandenbogaerde, Bernard Himpens
Publikováno v:
Scopus-Elsevier
The toxicity on three human tumor cell lines (A431, HeLa and MCF7) of five phenanthroperylenequinones (hypericin and derivatives) and two perylenequinones (cercosporin and calphostin C) was investigated after photosensitization (4 J/cm2). Furthermore
Publikováno v:
Photochemistry and photobiology. 74(2)
In the present study, hypericin analogs with an increased hydrophilic character were synthesized. As chemical modifications alter the lipophilicity/hydrophilicity balance together with the photophysical/chemical background of the molecule the influen
Publikováno v:
Photochemistry and photobiology. 74(2)
We have previously shown that the rhodacyanine dye, Rhodac, exhibits a potent photocytotoxic activity in HeLa cells. In this study several aspects of the photobiological activity of Rhodac were further examined. Rhodac displayed no selective cytotoxi
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 55(1)
The present work has been carried out to explore the potential application of cyanines in photodynamic therapy. After photosensitization, the in vitro cytotoxic and antiproliferative activity on HeLa cells of a total of 35 cyanines belonging to sever
Publikováno v:
Planta medica. 65(8)
In the present study, protohypericin was synthesised in order to compare its intrinsic photocytotoxicity with that of hypericin. The experimental work was performed in specific filtered light conditions that prevented both an unintended photoconversi
Autor:
A L, Vandenbogaerde, E M, Delaey, A M, Vantieghem, B E, Himpens, W J, Merlevede, P A, de Witte
Publikováno v:
Photochemistry and photobiology. 67(1)
The toxicity on three human tumor cell lines (A431, HeLa and MCF7) of five phenanthroperylenequinones (hypericin and derivatives) and two perylenequinones (cercosporin and calphostin C) was investigated after photosensitization (4 J/cm2). Furthermore