Zobrazeno 1 - 10
of 693
pro vyhledávání: '"E. Lippman"'
Stay on top of the latest knowledge in the field with this must-have resource for all clinicians who treat breast diseases. Expand your knowledge of every aspect of breast diseases as a diverse and distinguished group of internationally-recognized ex
Autor:
Chloe J. Taub, Alain Diaz, Bonnie B. Blomberg, Devika R. Jutagir, Hannah M. Fisher, Lisa M. Gudenkauf, Marc E. Lippman, Barry I. Hudson, Michael H. Antoni
Publikováno v:
Psychosomatic medicine. 84(7)
Elevated inflammation and psychological distress in patients with breast cancer (BCa) have been related to poorer health outcomes. Regulation of the hypothalamic-pituitary-adrenal axis and signaling of the receptor for advanced glycation end products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16b090d75b42d1c86132eb312df17a31
https://pubmed.ncbi.nlm.nih.gov/35980780
https://pubmed.ncbi.nlm.nih.gov/35980780
Publikováno v:
Cancer Research. 82:P1-08
Background: The human apolipoprotein E (APOE) gene has three major allelic variants: APOE2, -E3 and -E4. Carriers of the E4 allele are at increased risk for Alzheimer’s and other age-related neurodegenerative disorders. Recently, APOE4 has been ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11456623b74d2b27137210f69ae86ba2
https://doi.org/10.1158/1538-7445.sabcs21-p1-08-05
https://doi.org/10.1158/1538-7445.sabcs21-p1-08-05
Supplementary Figure 1. A) Rac1 DNA copy number in blood, normal prostate, and prostate adenocarcinoma from patients in the TCGA PRAD dataset B) Rac1 mRNA expression of normal prostate and prostate adenocarcinoma from the TCGA PRAD dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cd65b53b8fb2f45ad6ab4fa4c545d7
https://doi.org/10.1158/1535-7163.22522678
https://doi.org/10.1158/1535-7163.22522678
Supplemental Figure 1. Rac1 is a driver of ccRCC. (A) Rac1 mRNA expression in normal kidney and ccRCC patients from Jones Renal Cohort. (B) Rac1 DNA copy number analysis of normal blood, normal kidney, and kidney tumors from the KIRC TCGA dataset. (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086fbe27dfb087e23f8f0b1bd09d46e4
https://doi.org/10.1158/1535-7163.22520851
https://doi.org/10.1158/1535-7163.22520851
Autor:
Marc E. Lippman, Adriana De La Garza, Dayrelis T. Mesa Lopez, Pallavi Chaturvedi, Erik T. Goka
Figure S1 shows Rac1 expression analysis of Normal Colon and Colon Adenocarcinoma patients obtained from the TCGA COAD dataset using Oncomine. Data is represented as Log2 Median centered ratio.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1971083d607cda0cbd0746e43ef7207b
https://doi.org/10.1158/1535-7163.22510693.v1
https://doi.org/10.1158/1535-7163.22510693.v1
Supplemental Figure 2. HACE1 overexpression reduces activated Rac1 and attenuates ccRCC growth and survival. (A) Rac1 and HACE1 mRNA expression correlation from the KIRC TCGA Dataset (B) Rac1-GTP Pull-down assay of empty vector or HACE1 overexpressin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e065093048929aa8b49bdcf2a058b6
https://doi.org/10.1158/1535-7163.22520848
https://doi.org/10.1158/1535-7163.22520848
Autor:
Marc E. Lippman, Adriana De La Garza, Dayrelis T. Mesa Lopez, Pallavi Chaturvedi, Erik T. Goka
Resistance to chemotherapy represents a major limitation in the treatment of colorectal cancer. Novel strategies to circumvent resistance are critical to prolonging patient survival. Rac1b, a constitutively activated isoform of the small GTPase Rac1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae18a6ed14a9f18a462950fdfc154ed
https://doi.org/10.1158/1535-7163.c.6539680
https://doi.org/10.1158/1535-7163.c.6539680
Clear cell renal cell carcinoma (ccRCC) remains a common cause of cancer mortality. Better understanding of ccRCC molecular drivers resulted in the development of antiangiogenic therapies that block the blood vessels that supply tumors with nutrients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adcd074a0df5b1e87a152d210b5b1b0
https://doi.org/10.1158/1535-7163.c.6542812.v1
https://doi.org/10.1158/1535-7163.c.6542812.v1
Supplemental Figure 3. In vitro and In Vivo characterization of GYS32661. (A) Cellular proliferation assay of 786-O cells treated with vehicle, 2.5, and 5 μM GYS32661. (B) Plasma and tumor concentrations of GYS32661 at 0.25, 1, 4, and 8 hour t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26163115917bc2a151f9a1f56b5c33a1
https://doi.org/10.1158/1535-7163.22520845.v1
https://doi.org/10.1158/1535-7163.22520845.v1