Zobrazeno 1 - 10 of 27 pro vyhledávání: '"E. Laura Moyano"'
1
Akademický článek
Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3
Autor: M. Lourdes Sciú, Victor Sebastián-Pérez, Loreto Martinez-Gonzalez, Rocio Benitez, Daniel I. Perez, Concepción Pérez, Nuria E. Campillo, Ana Martinez, E. Laura Moyano
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 87-96 (2019)
Numerous studies have highlighted the implications of the glycogen synthase kinase 3 (GSK-3) in several processes associated with Alzheimer’s disease (AD). Therefore, GSK-3 has become a crucial therapeutic target for the treatment of this neurodege
Externí odkaz: https://doaj.org/article/02eaf3ea1ac54fe49215488f90ef2ccd
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2
Akademický článek
Biochars from Spirulina as an alternative material in the purification of lactic acid from a fermentation broth
Autor: Roxana Verónica Piloni, Luciana Fontes Coelho, Daiane Cristina Sass, Mario Lanteri, Maria Aparecida Zaghete Bertochi, E. Laura Moyano, Jonas Contiero
Publikováno v: Current Research in Green and Sustainable Chemistry, Vol 4, Iss , Pp 100084- (2021)
In this study, Spirulina biochar obtained from fast pyrolysis was evaluated as an alternative to commercial activated carbon for lactic acid (LA) purification from a fermentation broth. Thermally (350 and 400 ​°C treatment of the biochar in N2 atm
Externí odkaz: https://doaj.org/article/d773de96144e4a4f8e97edf89df605fb
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3
Akademický článek
Synthesis and preliminary structure-activity relationship study of 2-aryl-2H-pyrazolo[4,3-c]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors
Autor: Ivana Malvacio, Alberto Cuzzolin, Mattia Sturlese, D. Mariano A. Vera, E. Laura Moyano, Stefano Moro
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 171-183 (2018)
The serine-threonine checkpoint kinase 1 (Chk1) plays a critical role in the cell cycle arrest in response to DNA damage. In the last decade, Chk1 inhibitors have emerged as a novel therapeutic strategy to potentiate the anti-tumour efficacy of cytot
Externí odkaz: https://doaj.org/article/5f64f7eec8024ce68274172a772c8777
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8
Uncovering the Mechanism Leading to the Synthesis of Symmetric and Asymmetric Tröger′s Bases
Autor: Alejandro R. Parise, E. Laura Moyano, Diego Dusso, D. Mariano A. Vera, Carlos A. Chesta, Priscila A. Lanza, Cristina L. Ramírez
Publikováno v: European Journal of Organic Chemistry. 2019:7644-7655
Fil: Lanza, Priscila Ailin. Universidad Nacional de Mar del Plata; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Mar del Plata. Instituto de Investigaciones En Biodiversidad y Biotecnol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64d6d2720d062414b4b5678ae569b92a
https://doi.org/10.1002/ejoc.201901141
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10
Identification of pyrazolotriazinones as potential agents for hyperuricemia treatment by using in vitro and in silico studies
Autor: E. Laura Moyano, M. Daniela Santi, Jorge Cantero, Juan P. Colomer, M. Gabriela Ortega, M. Lourdes Sciú, Margot Paulino-Zunini
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Heterocyclic compounds structurally related to purine bases have been described as anticonvulsants, antifungal, antiviral, anticancer, enzyme inhibitors, among others. In this work, pyrazolo[3,4-d][1-3]triazin-4-ones (2) and pyrazolo[4,3-d][1-3]triaz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ad8ce0671ede86801fb017195d8b19
https://doi.org/10.1007/s42452-020-2756-6
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