Zobrazeno 1 - 10
of 63
pro vyhledávání: '"E. Landree"'
Autor:
Leslie E. Landree, Francis P. Kuhajda, Edward A. Wydysh, Khadija Daniels, Yajun Tu, Wan Fang Han, Susan M. Medghalchi, Jonathan M. Peterson, Craig A. Townsend, Kody Wong, Gabriele V. Ronnett, Susan Aja, Rajaa El Meskini
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 301:R116-R130
Storage of excess calories as triglycerides is central to obesity and its associated disorders. Glycerol-3-phosphate acyltransferases (GPATs) catalyze the initial step in acylglyceride syntheses, including triglyceride synthesis. We utilized a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d90a0025cb30411f85b3328e144809b
https://doi.org/10.1152/ajpregu.00147.2011
https://doi.org/10.1152/ajpregu.00147.2011
Autor:
Matthew H. Kemm, Leslie E. Landree, Jagan N. Thupari, Francis P. Kuhajda, Jayson Hyun, Susan M. Medghalchi, Khadija Daniels, Erica Plummer, Andrea Aplasca, Susan Aja, Amy M. Kleman, Gabriele V. Ronnett, Craig A. Townsend, Aravinda Vadlamudi, Jill M. McFadden, Timothy H. Moran
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 294:R352-R361
Inhibition of brain carnitine palmitoyl-transferase-1 (CPT-1) is reported to decrease food intake and body weight in rats. Yet, the fatty acid synthase (FAS) inhibitor and CPT-1 stimulator C75 produces hypophagia and weight loss when given to rodents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501cd28916cdcec594873dcd0ed7cff6
https://doi.org/10.1152/ajpregu.00862.2006
https://doi.org/10.1152/ajpregu.00862.2006
Autor:
Gabriele V. Ronnett, Leslie E. Landree, Louise D. McCullough, Francis P. Kuhajda, Eun Kyoung Kim
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 6:15-25
The regulation of cellular energy homeostasis within the CNS is crucial not only to neuronal survival, but to the brains function as an integrator of hormonal and neural inputs that regulate many functions, such as feeding behavior. The sensing and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::869e30c4b18a9f2febc438ab3d1b7bfe
https://doi.org/10.2174/187152406776056564
https://doi.org/10.2174/187152406776056564
Publikováno v:
Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents. 5:439-450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f768808855f9cefd114552fe1c504c7b
https://doi.org/10.2174/156801305774322402
https://doi.org/10.2174/156801305774322402
Publikováno v:
Physiology & Behavior. 85:25-35
Although metabolites and energy balance have long been known to play roles in the regulation of food intake, the potential role of fatty acid metabolism in this process has been considered only recently. Fatty acid synthase (FAS) catalyzes the conden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72732ddc480eeb31271868dd05e36a1
https://doi.org/10.1016/j.physbeh.2005.04.014
https://doi.org/10.1016/j.physbeh.2005.04.014
Autor:
Francis P. Kuhajda, Eun Kyoung Kim, Leslie E. Landree, Susan Aja, Michael L. Pinn, Jill M. McFadden, Ian Miller, Timothy H. Moran, Gabriele V. Ronnett
Publikováno v:
Journal of Biological Chemistry. 279:19970-19976
Energy homeostasis and feeding are regulated by the central nervous system. C75, a fatty acid synthase (FAS) inhibitor, causes weight loss and anorexia, implying a novel central nervous system pathway(s) for sensing energy balance. AMP-activated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edf7aa4b7f10a1199b625063bae78ef
https://doi.org/10.1074/jbc.m402165200
https://doi.org/10.1074/jbc.m402165200
Publikováno v:
Proceedings of the National Academy of Sciences. 99:9498-9502
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an α-methylene-γ-butyrolactone, reduces adipose tissue and fatty liver,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b6530ef86365f2bc768f8075bbbb08f
https://doi.org/10.1073/pnas.132128899
https://doi.org/10.1073/pnas.132128899
Publikováno v:
Science. 285:1719-1722
A method based on a controlled solid-solid reaction was used to fabricate heterostructures between single-walled carbon nanotubes (SWCNTs) and nanorods or particles of silicon carbide and transition metal carbides. Characterization by high-resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e993d8c1450bbff1fe198c4029134a
https://doi.org/10.1126/science.285.5434.1719
https://doi.org/10.1126/science.285.5434.1719
Publikováno v:
Microscopy Research and Technique. 46:160-177
Surface structure analysis is an important area of research, and in recent years notable advances have been made in this field, both in improved techniques for studying surfaces and in methods of analyzing them. This review aims to summarize the tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa5c8708f285695bf14b3a2aae900bf6
https://doi.org/10.1002/(sici)1097-0029(19990801)46:3<160::aid-jemt2>3.0.co
https://doi.org/10.1002/(sici)1097-0029(19990801)46:3<160::aid-jemt2>3.0.co
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 55:601-612
The connection between the crystallographic phase problem and the feasible set approach is explored. It is argued that solving the crystallographic phase problem is formally equivalent to a feasible set problem using a statistical operator interpreta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a2e3512af6e74993291725656b871b
https://doi.org/10.1107/s0108767398014408
https://doi.org/10.1107/s0108767398014408