Zobrazeno 1 - 10
of 368
pro vyhledávání: '"E. L. Hewlett"'
Publikováno v:
The Journal of Immunology. 145:1537-1544
Human rTNF-alpha (greater than or equal to U/ml) decreased PMN nondirected and directed migration to FMLP to approximately 50% of control. Adenosine (100 microM) almost completely restored hrTNF-inhibited migration (nondirected from 54 to 92% and dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6d5c032937ad395db11667b59a2be7
https://doi.org/10.4049/jimmunol.145.5.1537
https://doi.org/10.4049/jimmunol.145.5.1537
Publikováno v:
Infection and Immunity. 58:1402-1407
We examined the effect of protein kinase C (PKC) activation on the cyclic GMP response to heat-stable enterotoxin (STa) in a colonic carcinoma intestinal epithelial cell line, T84 cells. Our results demonstrate that the active phorbol ester analog, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bee803b752463fef4b1f3f17695b691
https://doi.org/10.1128/iai.58.5.1402-1407.1990
https://doi.org/10.1128/iai.58.5.1402-1407.1990
Publikováno v:
Molecular microbiology. 53(6)
Adenylate cyclase (AC) toxin is present on the surface of Bordetella pertussis organisms and their addition to eukaryotic cells results in increases in intracellular cAMP. To test the hypothesis that surface-bound toxin is the source for intoxication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa2b71f191eaa9c554aed96fe6bbfd52
https://pubmed.ncbi.nlm.nih.gov/15341649
https://pubmed.ncbi.nlm.nih.gov/15341649
Autor:
E L, Hewlett
Publikováno v:
Developments in biological standardization. 89
An evaluation of possible relationships between the preparation and content of acellular pertussis vaccines and their efficacy reveals that, in most instances, there is much more extensive variability in content and mode of preparation of these produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0ac8905b98124fc38018f3cd82d6a2c
https://pubmed.ncbi.nlm.nih.gov/9272344
https://pubmed.ncbi.nlm.nih.gov/9272344
Autor:
E L, Hewlett
Publikováno v:
Pediatrics. 98(4 Pt 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb019093196edf3b06d89f89c11778df
https://pubmed.ncbi.nlm.nih.gov/7659475
https://pubmed.ncbi.nlm.nih.gov/7659475
Publikováno v:
Canadian journal of physiology and pharmacology. 74(1)
The mechanism by which adenosine 5'-triphosphate (ATP) shortens atrial action potential duration was studied in a canine model in vivo. Previous studies have indicated that the negative chronotropic and dromotropic actions of ATP in the canine heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84621a8510bc7321d919de3bb46dbccd
https://pubmed.ncbi.nlm.nih.gov/8963948
https://pubmed.ncbi.nlm.nih.gov/8963948
Publikováno v:
The Journal of biological chemistry. 269(36)
Adenylate cyclase toxin (AC toxin) from Bordetella pertussis enters target cells to produce supraphysiologic levels of cAMP and, by a cAMP-independent process, is hemolytic. In the present study, we show for the first time that this toxin also produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9773c1ff574ca88faaffc4982f8105df
https://pubmed.ncbi.nlm.nih.gov/8077197
https://pubmed.ncbi.nlm.nih.gov/8077197
Autor:
E L, Hewlett, M C, Gray, I E, Ehrmann, N J, Maloney, A S, Otero, L, Gray, M, Allietta, G, Szabo, A A, Weiss, E M, Barry
Publikováno v:
The Journal of biological chemistry. 268(11)
Bordetella pertussis adenylate cyclase (AC) toxin has the abilities to 1) enter target cells where it catalyzes cyclic AMP production and 2) lyse sheep erythrocytes, and these abilities require post-translational modification by the product of an acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab34c59cfd577999bfbea0f689262b9d
https://pubmed.ncbi.nlm.nih.gov/8385122
https://pubmed.ncbi.nlm.nih.gov/8385122
Publikováno v:
The Journal of biological chemistry. 266(26)
Adenylate cyclase (AC) toxin from Bordetella pertussis interacts with and enters eukaryotic cells to catalyze the production of supraphysiologic levels of cyclic AMP. Although the calmodulin-activated enzymatic activity (ability to convert ATP to cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::810ef81990ee777bd9a769fd5fcdf319
https://pubmed.ncbi.nlm.nih.gov/1894634
https://pubmed.ncbi.nlm.nih.gov/1894634
Autor:
McCoy, Reece1 (AUTHOR), Oldroyd, Sophie1 (AUTHOR), Yang, Woojin1,2 (AUTHOR), Wang, Kaixin1 (AUTHOR), Hoven, Darius1 (AUTHOR), Bulmer, David3 (AUTHOR), Zilbauer, Matthias2 (AUTHOR), Owens, Róisín M.1 (AUTHOR) rmo37@cam.ac.uk
Publikováno v:
Advanced Science. 2/23/2024, Vol. 11 Issue 8, p1-36. 36p.