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Akademický článek

M urraya koenigii (L.) Sprengel seeds and pericarps in relation to their chemical profiles: new approach for multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia

Autor: Riham A. El-Shiekh, Rana Elshimy, Asmaa A. Mandour, Hanaa A. H. Kassem, Amal E. Khaleel, Saleh Alseekh, Alisdair R. Fernie, Mohamed A. Salem

Publikováno v: Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-19 (2024)

Abstract Acinetobacter baumannii is without a doubt one of the most problematic bacteria causing hospital-acquired nosocomial infections in today's healthcare system. To solve the high prevalence of multi-drug resistant (MDR) in A. baumannii, we inve

Externí odkaz: https://doaj.org/article/00596760958d4d79ad425be63e4df277

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Akademický článek

Cytotoxic and antiviral activities of Jatropha variegata and Jatropha spinosa in relation to their metabolite profile

Autor: Khawlah Shari, Osama G. Mohamed, Khaled M. Meselhy, Ashootosh Tripathi, Amal E. Khaleel, Essam Abdel-Sattar, Rania A. El Gedaily

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

Abstract Jatropha variegata and Jatropha spinosa (family: Euphorbiaceae) are utilized in Yemeni traditional medicine to treat respiratory tract infection and in different skin conditions such as wound healing, as antibacterial and hemostatic. In this

Externí odkaz: https://doaj.org/article/7fc2253fb14e484aa3e5504752953dde

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Akademický článek

Evaluation of exercise capacity in chronic obstructive pulmonary disease patients with pulmonary hypertension

Autor: Ashraf Z E-A Mohamed, Lamiaa H Shaaban, Amira E E-d Abdalah, Ali Tohamy, Waleed G E Khaleel

Publikováno v: Egyptian Journal of Chest Disease and Tuberculosis, Vol 73, Iss 1, Pp 54-64 (2024)

Background Chronic obstructive pulmonary disease (COPD) is ordinarily associated with social and economic burden. Pulmonary hypertension attributed to COPD varies greatly among studies; and accounts for worse quality of life and hence increased morbi

Externí odkaz: https://doaj.org/article/8e5171be165242bc996171921bc85ce4

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Akademický článek

Correlation between secondary metabolites of Iris confusa Sealy and Iris pseudacorus L. and their newly explored antiprotozoal potentials

Autor: Passent M. Abdel-Baki, Moshera M. El-Sherei, Amal E. Khaleel, Essam Abdel-Sattar, Mohamed A. Salem, Mona M. Okba

Publikováno v: BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-16 (2023)

Abstract Background In the last few decades, the use of plant extracts and their phytochemicals as candidates for the management of parasitic diseases has increased tremendously. Irises are aromatic and medicinal plants that have long been employed i

Externí odkaz: https://doaj.org/article/8b2029ec046541f8ac9105e9ee4f9887

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Akademický článek

Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells

Autor: Khawlah Shari, Rania A. El Gedaily, Rasha M. Allam, Khaled M. Meselhy, Amal E. Khaleel, Essam Abdel-Sattar

Publikováno v: BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-10 (2023)

Abstract Background Breast cancer is a prevalent malignant tumor that affects women worldwide. The primary challenge in treating breast cancer is combating drug resistance, which contributes to relapse and metastasis. Jatrophone is a unique macrocycl

Externí odkaz: https://doaj.org/article/6528cc7286f14d27b0fe9f29b7c11509

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Akademický článek

Irigenin, a novel lead from Iris confusa for management of Helicobacter pylori infection with selective COX-2 and HpIMPDH inhibitory potential

Autor: Passent M. Abdel-Baki, Moshera M. El-Sherei, Amal E. Khaleel, Marwa M. Abdel-Aziz, Mona M. Okba

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract The development of new natural drugs for Helicobacter pylori (H. pylori) management has recently received significant attention. Iris confusa (I. confusa) was long used for the treatment of bacterial infections and gastritis. This study aime

Externí odkaz: https://doaj.org/article/84af5a718961439b93bca6320b012c10

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Akademický článek

Isolated cutaneous Pseudallescheria boydii abscess in an immunocompetent man

Autor: Connor J. Stonesifer, BA, Alexandra E. Khaleel, BA, Tiffany J. Garcia-Saleem, MD, Sameera Husain, MD, Larisa J. Geskin, MD

Publikováno v: JAAD Case Reports, Vol 21, Iss , Pp 160-164 (2022)

Externí odkaz: https://doaj.org/article/523a5e6f33564f6b96efca0eaa4d543b

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Akademický článek

Immune Checkpoint Inhibition in Non-Melanoma Skin Cancer: A Review of Current Evidence

Autor: Connor J. Stonesifer, A. Reza Djavid, Joseph M. Grimes, Alexandra E. Khaleel, Yssra S. Soliman, Amanda Maisel-Campbell, Tiffany J. Garcia-Saleem, Larisa J. Geskin, Richard D. Carvajal

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Immuno-oncology is a rapidly evolving field with growing relevance in the treatment of numerous malignancies. The prior study of immunotherapy in dermatologic oncology has largely focused on cutaneous melanoma. However, recent focus has shifted to th

Externí odkaz: https://doaj.org/article/f12053fcd40c4fbda69da7fa92d7bb4a

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