Zobrazeno 1 - 10
of 19
pro vyhledávání: '"E. Kemmerich"'
Autor:
Marius Rutkauskas, Inga Songailiene, Patrick Irmisch, Felix E. Kemmerich, Tomas Sinkunas, Virginijus Siksnys, Ralf Seidel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Based on thorough single-molecule analysis of off-target binding by the CRISPR-Cas surveillance complex Cascade, a mechanism-based model is presented that quantitatively describes the recognition dynamics of mutated targets by this protein.
Externí odkaz:
https://doaj.org/article/c899fa03b0a74176bb9813625f974959
Autor:
Pierre Aldag, Marius Rutkauskas, Julene Madariaga-Marcos, Inga Songailiene, Tomas Sinkunas, Felix E Kemmerich, Dominik J Kauert, Virginijus Siksnys, Ralf Seidel
CRISPR-Cas effector complexes enable the defense against foreign nucleic acids and have recently been exploited as molecular tools for precise genome editing at a target locus. To bind and cleave their target, the CRISPR-Cas effectors first have to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466430953456cc1be4b1c98eb0173af7
https://doi.org/10.1101/2022.12.18.520913
https://doi.org/10.1101/2022.12.18.520913
Publikováno v:
Methods. 108:4-13
Magnetic tweezers provide a versatile toolkit supporting the mechanistic investigation of helicases. In the present article, we show that custom magnetic tweezers setups are straightforward to construct and can easily be extended to provide adaptable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efbadbe78045a0048c560ffe8d63a7a
https://doi.org/10.1016/j.ymeth.2016.07.004
https://doi.org/10.1016/j.ymeth.2016.07.004
Publikováno v:
Nucleic Acids Research
Nucleic acids research
Nucleic acids research
Replication protein A (RPA) is a single-stranded DNA binding protein, involved in most aspects of eukaryotic DNA metabolism. Here, we study the behavior of RPA on a DNA substrate that mimics a replication fork. Using magnetic tweezers we show that bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1ab0041153a426d9a6c1519b1a0705
http://europepmc.org/articles/PMC4937307
http://europepmc.org/articles/PMC4937307
Autor:
Ralf Seidel, Pierre Aldag, Felix E. Kemmerich, Inga Songailiene, Julene Madariaga Marcos, Virginijus Siksnys
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d17ac825ac8d9bdb9af89b81c5bcb4
https://doi.org/10.1016/j.bpj.2017.11.1392
https://doi.org/10.1016/j.bpj.2017.11.1392
Autor:
Steffen Hahn, M. Svea Grieb, Felix E. Kemmerich, Michael Schlierf, Marko Swoboda, Dominik J. Kauert, Ralf Seidel, Friedrich W. Schwarz
Publikováno v:
Nano letters. 16(1)
We present a hybrid single-molecule technique combining magnetic tweezers and Forster resonance energy transfer (FRET) measurements. Through applying external forces to a paramagnetic sphere, we induce conformational changes in DNA nanostructures, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fd132f68921e7215ae8810510dc953
https://pubmed.ncbi.nlm.nih.gov/26632021
https://pubmed.ncbi.nlm.nih.gov/26632021
Autor:
Hakim Meskine, Viktor Bezugly, Felix E. Kemmerich, Gianaurelio Cuniberti, Jens Kunstmann, Hagen Eckert
Publikováno v:
Physical Review B. 87
The zone-folding method is a widely used technique in computing the electronic structure of carbon nanotubes. In this paper, curvature effects of boron and carbon nanotubes of different diameters and chiralities are systematically quantified using th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bda3d2726d897b9c403ac36a2edb890
https://doi.org/10.1103/physrevb.87.245409
https://doi.org/10.1103/physrevb.87.245409
Autor:
Daniel Klaue, Felix E. Kemmerich, Ralf Seidel, Alicja Kozikowska, Daniela Kobbe, Holger Puchta
Publikováno v:
Nature Communications
RecQ helicases have essential roles in maintaining genome stability during replication and in controlling double-strand break repair by homologous recombination. Little is known about how the different RecQ helicases found in higher eukaryotes achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10bf5609b056df4847a87e81b525d2d
https://pubmed.ncbi.nlm.nih.gov/23771268
https://pubmed.ncbi.nlm.nih.gov/23771268
Autor:
E. Kemmerich
Publikováno v:
bchm. 18:409-422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d5c2a642064b318f4767e6901108f1
https://doi.org/10.1515/bchm1.1894.18.5-6.409
https://doi.org/10.1515/bchm1.1894.18.5-6.409
Autor:
E. Kemmerich
Publikováno v:
Pflüger, Archiv für die Gesammte Physiologie des Menschen und der Thiere. 1:120-124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07552b0db3c1bde1ead0ca1fb8fa6662
https://doi.org/10.1007/bf01640313
https://doi.org/10.1007/bf01640313