Zobrazeno 1 - 10
of 71
pro vyhledávání: '"E. K. Jackson"'
Publikováno v:
Oncoimmunology. 5(2)
CD39 and CD73 are key enzymes in the adenosine (ADO) pathway. ADO modulates pathophysiological responses of immune cells, including B cells. It has recently emerged that a subpopulation of ADO-producing CD39+CD73+ B cells has regulatory properties. H
Publikováno v:
Revista Panamericana de Salud Pública, Vol 4, Iss 2, Pp 100-105 (1998)
El cambio climático debido a actividades humanas pone en peligro los ecosistemas y la salud humana a escala mundial. Con el fin de hacer frente a las amenazas que se ciernen sobre los ecosistemas en todo el mundo, en el decenio de 1980 se introdujo
Publikováno v:
Research communications in molecular pathology and pharmacology. 110(1-2)
Sepsis depletes intracellular stores of ATP and NAD+, leading to cellular energy failure. Liposome encapsulation improves intracellular delivery of bulky, charged molecules and substrates susceptible to extracellular enzyme degradation. We hypothesiz
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(3)
A pandemic of obesity is contributing importantly to the prevalence of the metabolic syndrome characterized by hypertension, insulin resistance, and hyperlipidemia. In turn, the metabolic syndrome is contributing to vascular disease and the accelerat
Autor:
R K, Dubey, E K, Jackson
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 91(4)
17beta-estradiol (estradiol), the most abundant endogenous estrogen, affords cardiovascular protection. However, in a given cohort of postmenopausal women, estradiol replacement therapy provides cardiovascular protection in only a subset. The reasons
Autor:
C L, Robertson, K S, Hendrich, P M, Kochanek, E K, Jackson, J A, Melick, S H, Graham, D W, Marion, D S, Williams, C, Ho
Publikováno v:
Acta neurochirurgica. Supplement. 76
Adenosine is a putative endogenous neuroprotectant. Its action at A1 receptors mitigates excitotoxicity while action at A2 receptors increases cerebral blood flow (CBF). We hypothesized that cerebral injection of the adenosine analog, 2-chloroadenosi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(1)
To examine the effects of chronic type IV phosphodiesterase (PDE4) inhibition on renal function and renal and mesenteric vascular resistance and blood flow in a sublethal model of multiple organ dysfunction syndrome (MODS) we used a prospective, rand
Publikováno v:
Molecular and cellular biochemistry. 212(1-2)
Altered regulation of cAMP may contribute to enhanced renal reactivity to angiotensin II (Ang II) in spontaneously hypertensive rats (SHR). Such a phenomenon may occur in renal preglomerular arterioles and may involve changes in expression of GTP-bin
Publikováno v:
Alimentary pharmacologytherapeutics. 14(10)
Adenosine exerts actions which may be beneficial in treating diseases of the gastrointestinal tract. However, administered systemically, adenosine causes a 'stress reaction' and may adversely affect blood pressure and cardiac and renal function.To de
Autor:
E K, Jackson, Z, Mi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(1)
The purpose of this study was to investigate whether the extracellular cAMP-adenosine pathway (i.e., transport of cAMP out of cells followed by extracellular conversion of cAMP to adenosine) exists in preglomerular microvessels (PGMVs). Incubation of