Zobrazeno 1 - 10
of 10
pro vyhledávání: '"E. K. Haywood"'
Autor:
Bernard J Morley, SJ Rose, Stuart Horswell, G Fu, Mark Walport, Michelle E. K. Haywood, MJ Lees
Publikováno v:
Genes & Immunity. 7:250-263
The BXSB mouse strain is an important model of glomerulonephritis observed in systemic lupus erythematosus (SLE). Linkage studies have successfully identified disease-susceptibility intervals; however, extracting the identity of the susceptibility ge
Autor:
Akinori Ida, Shozo Izui, EM Thompson, Aileen McDermott, Bernard J Morley, Michelle E. K. Haywood, Timothy J. Vyse, Mark Walport
Publikováno v:
The Journal of Immunology. 167:1728-1733
Retroviral envelope glycoprotein gp70 is present in the sera of immunologically normal and autoimmune-prone strains of mice. However, only lupus-prone mice spontaneously develop gp70-anti-gp70 immune complexes (gp70IC), and these have been implicated
Publikováno v:
Immunogenetics. 51:370-372
Publikováno v:
Photochemistry and Photobiology. 54:781-788
The long-term data base on atmospheric ozone combined with a set of radiative transfer calculations provides estimates of the variability in ultraviolet (UV) sunlight that should have occurred over the period1957–1988 under clear, pollution-free sk
Autor:
L Gabriel, Shozo Izui, S. Jane Rose, Bernard J Morley, Nicola J. Rogers, Michelle E. K. Haywood
Publikováno v:
Journal of Immunology, Vol. 179, No 4 (2007) pp. 2428-2434
The BXSB strain of recombinant inbred mice develops a spontaneous pathology that closely resembles the human disease systemic lupus erythematosus. Six non-MHC loci, Yaa, Bxs1–4, and Bxs6, have been linked to the development of aspects of the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d45afda2323fb51a5c0b9fdf55fb005
https://archive-ouverte.unige.ch/unige:11294
https://archive-ouverte.unige.ch/unige:11294
Publikováno v:
Genes and immunity. 6(4)
The activation-induced differentiation of naive CD4+ T cells generates functionally divergent type 1 helper T cells (Th1) or type 2 helper T cells (Th2) effector cell populations, characterized by secretion of Interferon (IFN)-gamma or Interleukin (I
Autor:
Bernard J Morley, Joanna M. Rankin, Aileen McDermott, Mark Walport, Nicola J. Rogers, Shozo Izui, Liliane Fossati-Jimack, Vasuky Thiruudaian, S. Jane Rose, Michelle E. K. Haywood, Margarita Lewis, Joseph J. Boyle
Publikováno v:
Journal of Immunology, Vol. 173, No 7 (2004) pp. 4277-4285
To dissect the individual effects of the four non-MHC, autosomal loci (Bxs1 to Bxs4) that contribute to SLE susceptibility in BXSB mice, we generated congenic lines from chromosome 1 on a C57BL/10.YBXSB (B10.Yaa) background for the intervals (values
BXSB mice develop a lupus-like autoimmune syndrome. We have previously identified several intervals that were linked to disease and, in an attempt to characterise lupus susceptibility genes within these intervals, we have sought to isolate differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e819ee1eb13eea992585c8a8f906a0e7
https://europepmc.org/articles/PMC101347/
https://europepmc.org/articles/PMC101347/
Autor:
Elizabeth Simpson, SJ Rose, MA Maibaum, Michelle E. K. Haywood, MB Hogarth, Kevin A. Davies, Phillip Chandler, PJ Allen, Mark Walport, JH Slingsby, Bernard J Morley, EM Thompson
Publikováno v:
Arthritis and rheumatism. 43(2)
Objective To identify intervals containing systemic lupus erythematosus (SLE) susceptibility alleles in the BXSB strain of mice. Methods We analyzed 286 (B10 × [B10 × BXSB]F1) backcross mice for a range of phenotypic traits associated with the deve
Publikováno v:
Photochemistry and Photobiology. 50:443-450
The biologically effective ultraviolet irradiance at the earth's surface varies with the elevation of the sun, the atmospheric ozone amount, and with the abundance of scatterers and absorbers of natural and anthropogenic origin. Taken alone, the repo