Zobrazeno 1 - 10
of 44
pro vyhledávání: '"E. Joan Blanchette-Mackie"'
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 214-225 (2000)
Combined lipase deficiency (cld) is a recessive mutation in mice that causes a severe lack of lipoprotein lipase (LPL) and hepatic lipase (HL) activities, hyperlipemia, and death within 3 days after birth. Earlier studies showed that inactive LPL and
Externí odkaz:
https://doaj.org/article/9bb567761e0d4c74a9be92c39ceae296
Autor:
Vargheese M. Chennathukuzhi, Peter McNamara, E. Joan Blanchette-Mackie, Jerome F. Strauss, Rossana Sapiro, Mei Zhang, Anne Marie Curtis, Jeff Bray, Zhibing Zhang, Maja Bucan, David Kapfhamer
Publikováno v:
Molecular and Cellular Biology. 22:7993-8004
cDNAs were cloned for the murine and human orthologues of Chlamydomonas PF20, a component of the alga axoneme central apparatus that is required for flagellar motility. The mammalian genes encode transcripts of 1.4 and 2.5 kb that are highly expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ece8630b0e0ed293e13f19800e54e9
https://doi.org/10.1128/mcb.22.22.7993-8004.2002
https://doi.org/10.1128/mcb.22.22.7993-8004.2002
Autor:
Shiv Srivastava, Mei Sun, E. Joan Blanchette-Mackie, Judd W. Moul, Lanfeng Ma, Mei Zhang, Zhiqiang Zou, Jia Li, Linda Xu, Mazen Makarem, Gyorgy Petrovics, Wei Zhang, Isabell A. Sesterhenn
Publikováno v:
Molecular Medicine. 8:655-663
BACKGROUND: Deletion of chromosome 16q is frequently associated with diverse tumors. Numerous studies strongly suggest the presence of one or more tumor suppressor genes on chromosome 16q22 to 16qter including the widely studied cadherin gene family.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63438862811ac73e646a115787cec2e4
https://doi.org/10.1007/bf03402176
https://doi.org/10.1007/bf03402176
Autor:
Federico Martinez, John A. Hanover, M E Comly, Toshio Fujimoto, E. Joan Blanchette-Mackie, Pei Liu, Nancy K. Dwyer, Mei Zhang, Jerome F. Strauss, Lane K. Christenson
Publikováno v:
Journal of Biological Chemistry. 277:33300-33310
This study demonstrates that the steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing protein, MLN64, participates in intracellular cholesterol trafficking. Analysis of the intracellular itinerary of MLN64 and MLN64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7521b2919785d490626c3b4d6b85c168
https://doi.org/10.1074/jbc.m200003200
https://doi.org/10.1074/jbc.m200003200
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 2, Pp 214-225 (2000)
Combined lipase deficiency (cld) is a recessive mutation in mice that causes a severe lack of lipoprotein lipase (LPL) and hepatic lipase (HL) activities, hyperlipemia, and death within 3 days after birth. Earlier studies showed that inactive LPL and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925408534740215adffc1a96e25d0c3f
http://www.sciencedirect.com/science/article/pii/S0022227520320551
http://www.sciencedirect.com/science/article/pii/S0022227520320551
Autor:
Jane M. Glick, Jerome F. Strauss, Shutish Patel, Hidemichi Watari, Peter G. Pentchev, E. Joan Blanchette-Mackie, Edward B. Neufeld, Gwo-Shing Sun, Nancy K. Dwyer
Publikováno v:
Experimental Cell Research. 255:56-66
Steroidogenic cells represent unique systems for the exploration of intracellular cholesterol trafficking. We employed cytochemical and biochemical methods to explore the expression, regulation, and function of the Niemann-Pick C1 protein (NPC1) in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b9ec9776809c138c373cf920ac1846
https://doi.org/10.1006/excr.1999.4774
https://doi.org/10.1006/excr.1999.4774
Autor:
John P. Incardona, Adele Cooney, Roscoe O. Brady, Eugene D. Carstea, Calvin F. Roff, Nancy K. Dwyer, E. Joan Blanchette-Mackie, Marc C. Patterson, Peter G. Pentchev, Edward B. Neufeld, Jerome F. Strauss, Kousaku Ohno, Sundar Suresh, Shutish C. Patel, Marie T. Vanier, Meryl E. Wastney, Jill A. Morris
Publikováno v:
Journal of Biological Chemistry. 274:9627-9635
Niemann-Pick C disease (NP-C) is a neurovisceral lysosomal storage disorder. A variety of studies have highlighted defective sterol trafficking from lysosomes in NP-C cells. However, the heterogeneous nature of additional accumulating metabolites sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb284b1995a817ea3f62d2a15c797d40
https://doi.org/10.1074/jbc.274.14.9627
https://doi.org/10.1074/jbc.274.14.9627
Autor:
E. Joan Blanchette-Mackie, Roscoe O. Brady, Nancy K. Dwyer, Jerome F. Strauss, Shutish C. Patel, Edward B. Neufeld, Hidemichi Watari, Jane M. Glick, Peter G. Pentchev
Publikováno v:
Proceedings of the National Academy of Sciences. 96:805-810
Niemann-Pick type C (NPC) disease is an inherited lipid storage disorder that affects the viscera and central nervous system. A characteristic feature of NPC cells is the lysosomal accumulation of low density lipoprotein-derived cholesterol. To eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8231a9bf60c05b598fb359742eccd84e
https://doi.org/10.1073/pnas.96.3.805
https://doi.org/10.1073/pnas.96.3.805
Publikováno v:
Journal of Laboratory and Clinical Medicine. 131:215-221
Glycosylphosphatidylinositol-anchored proteins (GPI-proteins) expressed on the outer leaflet of cell membranes are involved in diverse physiologic as well as pathologic processes in humans. Previously, we demonstrated the intercellular transfer of ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5486d54d6e4873f69facb86e0f6fe2
https://doi.org/10.1016/s0022-2143(98)90092-0
https://doi.org/10.1016/s0022-2143(98)90092-0
Autor:
Rivka Carmi, Laura Liscum, Marcella E. Comly, Christine R. Kaneski, Marsha Zeigler, Adele Cooney, Roscoe O. Brady, Yiannis A. Ioannou, Peter G. Pentchev, Marc C. Patterson, James W. Nagle, E. Joan Blanchette-Mackie, Maureen E. Higgins, David B. Krizman, J Sokol, Raymond R. O'Neill, Jill A. Morris, Jerome F. Strauss, Stephen L. Sturley, Christiano Cummings, O. P. van Diggelen, Ta-Yuan Chang, Edward B. Neufeld, Danilo A. Tagle, Katherine G. Coleman, Jessie Z. Gu, Kousaku Ohno, Stacie K. Loftus, M H Polymeropoulos, Nancy K. Dwyer, David Markie, Melissa A. Rosenfeld, Marie T. Vanier, Anthony Brown, Eugene D. Carstea, Milan Elleder, Dana Zhang, William J. Pavan
Publikováno v:
Science, 277, 228-231. American Association for the Advancement of Science
Niemann-Pick type C (NP-C) disease, a fatal neurovisceral disorder, is characterized by lysosomal accumulation of low density lipoprotein (LDL)–derived cholesterol. By positional cloning methods, a gene (NPC1)with insertion, deletion, and missense
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5537b8141c320370b8c9c9951d5ad1a0
https://doi.org/10.1126/science.277.5323.228
https://doi.org/10.1126/science.277.5323.228