Výsledky vyhledávání - "E. J. Ziegler"

Amebic meningoencephalitis caused by Balamuthia mandrillaris: case report and review

Autor: V. J. Iragui, L. D. Uber Zak, E. J. Ziegler, C. F. Denney, N. C. Karpinski, Sharon L. Reed, G. S. Visvesvara

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 25(6)

Balamuthia mandrillaris, formerly referred to as a leptomyxid ameba, is a free-living ameba that has recently been identified as a cause of meningoencephalitis. Previously, only two genera, Naegleria and Acanthamoeba, were recognized as causes of cen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df345d3617ebfa49055f06f9dceb7be3
https://pubmed.ncbi.nlm.nih.gov/9431377

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Influence of alterations in foregoing life-sustaining treatment practices on a clinical sepsis trial. The HA-1A Sepsis Study Group

Autor: C L, Sprung, L A, Eidelman, R, Pizov, C J, Fisher, E J, Ziegler, J C, Sadoff, R C, Straube, R V, McCloskey

Publikováno v: Critical care medicine. 25(3)

To evaluate the timing of foregoing life-sustaining treatments in patients enrolled in a sepsis trial and to determine their influence on patient outcome and trial results.Subset of patients in a prospective, randomized, double-blind, placebo-control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ffa02754c6a5c07ac34da18f536b7b42
https://pubmed.ncbi.nlm.nih.gov/9118650

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HA-1A. A human monoclonal antibody for the treatment of gram-negative sepsis

Autor: C R, Smith, R C, Straube, E J, Ziegler

Publikováno v: Infectious disease clinics of North America. 6(1)

HA-1A is a human monoclonal IgM antibody that binds to endotoxin. The results of the clinical trials of HA-1A demonstrate that HA-1A reduces mortality among patients with sepsis and gram-negative bacteremia. Secondary endpoints, including resolution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf4b3815d54b1a7ecbb109e91d3388cf
https://pubmed.ncbi.nlm.nih.gov/1578120

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Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group

Autor: E J, Ziegler, C J, Fisher, C L, Sprung, R C, Straube, J C, Sadoff, G E, Foulke, C H, Wortel, M P, Fink, R P, Dellinger, N N, Teng

Publikováno v: The New England journal of medicine. 324(7)

HA-1A is a human monoclonal IgM antibody that binds specifically to the lipid A domain of endotoxin and prevents death in laboratory animals with gram-negative bacteremia and endotoxemia.To evaluate the efficacy and safety of HA-1A, we conducted a ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b63161fa58efc2081f25a0adba1ba4bf
https://pubmed.ncbi.nlm.nih.gov/2057029

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Therapy of gram-negative sepsis in man with anti-endotoxin antibodies: a review

Autor: C H, Wortel, E J, Ziegler, S J, van Deventer

Publikováno v: Progress in clinical and biological research. 367

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::acf254d00714287edf16895fa0669b1a
https://pubmed.ncbi.nlm.nih.gov/1924425

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Neutralization of meningococcal endotoxin by antibody to core glycolipid

Autor: Charles E. Davis, K F Arnold, E J Ziegler

Publikováno v: The Journal of Experimental Medicine

Antibodies to Escherichia coli J5, a uridine 5'-diphosphate-galactose epimerase-less mutant of E. coli 0111, neutralized meningococcal endotoxemia from all three major capsular serogroups. We chose the dermal necrosis of the local Shwartzman phenomen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1c86fd0a179566109a5405009491e2
https://doi.org/10.1084/jem.147.4.1007

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Analysis of the fine specificity and cross-reactivity of monoclonal anti-lipid A antibodies

Autor: T N Kirkland, D E Colwell, S M Michalek, J R McGhee, E J Ziegler

Publikováno v: The Journal of Immunology. 137:3614-3619

We have investigated the fine specificity of anti-lipid A antibodies to identify conserved lipid A antigens. Because lipid A derived from many different Gram-negative bacteria has similar biologic activities, the conserved regions may be of particula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32613f7f48da0ccf2bb7edf3bf9bb82e
https://doi.org/10.4049/jimmunol.137.11.3614

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Inhibition of lipopolysaccharide activation of 7OZ/3 cells by anti-lipopolysaccharide antibodies

Autor: T N Kirkland, E J Ziegler, P Tobias, D C Ward, S M Michalek, J R McGhee, I Macher, K Urayama, B J Appelmelk

Publikováno v: The Journal of Immunology. 141:3208-3213

We have investigated the ability of mAb against LPS to inhibit LPS-induced activation of 7OZ/3 pre-B cells. The fine specificity and relative affinity of these mAb for lipid A and LPS were also determined. We found that antibodies inhibited only the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0b99e536e1d260a67906e1f6ee4e620
https://doi.org/10.4049/jimmunol.141.9.3208

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An immunoprotective monoclonal antibody to lipopolysaccharide

Autor: T N Kirkland, E J Ziegler

Publikováno v: The Journal of Immunology. 132:2590-2592

The ability of antisera against lipopolysaccharide (LPS) raised by immunization with gram-negative bacteria to prevent LPS toxicity and death from gram-negative bacteremia is well established. To demonstrate conclusively that the protective antibody

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e7d011c71fd8f21128af8e0208772f7
https://doi.org/10.4049/jimmunol.132.5.2590

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