Zobrazeno 1 - 10
of 38
pro vyhledávání: '"E. J. Mufson"'
Autor:
Lemoine, L., A. Ledreux, E. J. Mufson, S. E. Perez, G. Simic, E. Doran, I. Lott, S. Carroll, K. Bharani, S. Thomas, A. Gilmore, E. D. Hamlett, A. Nordberg, A. C. Granholm
Additional file 1: Supplemental Fig. 1: 3H-PIB/Amylo-Glo and 3H-THK5117/AT8 distribution in hippocampus of 1 LOAD a: 3H-PIB autoradiography, b:3H-THK5117 Autoradiography, c: Amylo-Glo, d:AT8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d287c5450400db9f8e652f034a0495c
Publikováno v:
Journal of Neuroscience Research. 31:327-335
It is well established that iron, which is of considerable importance for normal neurological function, is highly regulated in all organ systems. However, until recently, iron regulation in the nervous system has received little attention. This study
Publikováno v:
Cellular and molecular life sciences : CMLS. 65(12)
Galanin (GAL) and GAL receptors (GALRs) are overexpressed in degenerating brain regions associated with cognitive decline in Alzheimer’s disease (AD). The functional consequences of GAL plasticity in AD are unclear. GAL inhibits cholinergic transmi
Publikováno v:
Microscopy research and technique. 55(1)
Apolipoprotein E (ApoE) genotype is a risk factor for Alzheimer's disease (AD) but its relationship with neurofibrillary degeneration remains obscure. To further analyze this relationship, hippocampal, entorhinal, temporopolar, and insular cortices o
Autor:
N, Ghoshal, F, García-Sierra, Y, Fu, L A, Beckett, E J, Mufson, J, Kuret, R W, Berry, L I, Binder
Publikováno v:
Journal of neurochemistry. 77(5)
We have characterized a novel monoclonal antibody, Tau-66, raised against recombinant human tau. Immunohistochemistry using Tau-66 reveals a somatic-neuronal stain in the superior temporal gyrus (STG) that is more intense in Alzheimer's disease (AD)
Publikováno v:
The Journal of comparative neurology. 434(2)
The distribution of galaninergic immunoreactive (-ir) profiles was studied in the brain of colchicine-pretreated and non-pretreated mice. Galanin (GAL)-ir neurons and fibers were observed throughout all encephalic vesicles. Telencephalic GAL-ir neuro
Publikováno v:
Annals of neurology. 49(2)
Layer II of the entorhinal cortex contains the cells of origin for the perforant path, plays a critical role in memory processing, and consistently degenerates in end-stage Alzheimer's disease. The extent to which neuron loss in layer II of entorhina
Autor:
E J, Mufson, S Y, Ma, E J, Cochran, D A, Bennett, L A, Beckett, S, Jaffar, H U, Saragovi, J H, Kordower
Publikováno v:
The Journal of comparative neurology. 427(1)
Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals wit
Publikováno v:
The Journal of comparative neurology. 426(4)
Guanosine triphosphate cyclohydrolase I (GTPCHI) is a critical enzyme in catecholamine function and is rate limiting for the synthesis of the catecholamine co-factor tetrahydrobiopterin. The present study assessed the distribution of GTPCHI immunorea
Autor:
J H, Kordower, S, Palfi, E Y, Chen, S Y, Ma, T, Sendera, E J, Cochran, E J, Mufson, R, Penn, C G, Goetz, C D, Comella
Publikováno v:
Annals of neurology. 46(3)
As part of a safety and tolerability study, a 65-year-old man with Parkinson's disease (PD) received monthly intracerebroventricular injections of glial-derived neurotrophic factor (GDNF). His parkinsonism continued to worsen following intracerebrove