Zobrazeno 1 - 8
of 8
pro vyhledávání: '"E. J. M. van der Valk"'
Autor:
A. van der Laarse, Soban Umar, Douwe E. Atsma, E. E. van der Wall, M.J. Schalij, E. J. M. van der Valk
Publikováno v:
Molecular and Cellular Biochemistry. 320:75-84
Prolonged myocardial stretch typically leads to hypertrophy of cardiomyocytes. As integrins are cellular receptors of stretch, we hypothesize that integrin stimulation induces cardiomyocyte hypertrophy. Integrins of neonatal rat cardiomyocytes (NRCMs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f79553d45ecd04fb2b23ce7f215efc7
https://doi.org/10.1007/s11010-008-9900-8
https://doi.org/10.1007/s11010-008-9900-8
Publikováno v:
Pflügers Archiv. 451:588-595
The myocardial stretch-induced increase in intracellular [Ca2+] ([Ca2+]i) is considered to be caused by integrin stimulation. Myocardial stretch is also associated with increased nitric oxide (NO) formation. We hypothesised that NO is implicated in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9140509f0775eea041a224c697ff2f3e
https://doi.org/10.1007/s00424-005-1402-x
https://doi.org/10.1007/s00424-005-1402-x
Autor:
M.P. van Dieijen-Visser, Douwe E. Atsma, E. J. M. van der Valk, Etienne C.H.J. Michielsen, A. van der Laarse, Marleen H. M. Hessel, Wim Th. Hermens, M.J. Schalij, Wilhelmina H. Bax
Publikováno v:
Experimental and molecular pathology. 85(2)
Purpose We characterized the release kinetics of cardiac troponin I and T in relation to lactate dehydrogenase (LDH) from cardiomyocytes before and after the transition from reversible to irreversible cell damage. Methods Cardiomyocytes were exposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb01aecd46be25787eabeae8ff8d47f
https://pubmed.ncbi.nlm.nih.gov/18721805
https://pubmed.ncbi.nlm.nih.gov/18721805
Autor:
F.J.M. Van Ravels, L. Hollaar, E. J. M. van der Valk, Nicolaas A. P. Franken, C.T. Le, J. Wondergem, A. van der Laarse
Publikováno v:
European heart journal. 16(4)
The primary defence mechanism of myocytes against peroxides and peroxide-derived peroxyl and alkoxyl radicals is the glutathione redox cycle. The purpose of the present study was to increase the turnover rate of this cycle by stimulating the glutathi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69c9e44fbaa7a7a5b41dca9ab688103
https://pubmed.ncbi.nlm.nih.gov/7671903
https://pubmed.ncbi.nlm.nih.gov/7671903
Publikováno v:
Journal of molecular and cellular cardiology. 25(5)
Mammalian heart myocytes have a limited capacity to withstand the deleterious effects of free radical generating compounds. To assess the role of the glutathione redox cycle relative to this capacity, rat heart cell cultures were subjected for 90 min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f84fdd4ce4f12561caf6cd7e2e43f36
https://pubmed.ncbi.nlm.nih.gov/8104252
https://pubmed.ncbi.nlm.nih.gov/8104252
Publikováno v:
Cardiovascular research. 26(2)
Objective: The aim was to find effective protection of myocytes against peroxide induced damage in terms of preservation of contractile activity, protection against lipid peroxidation, and protection against cell death. Methods: The components of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa075c871119e381c4f8899f91723ba6
https://pubmed.ncbi.nlm.nih.gov/1571933
https://pubmed.ncbi.nlm.nih.gov/1571933
Autor:
A. van der Laarse, M.J. Schalij, Marleen H. M. Hessel, Wilhelmina H. Bax, Douwe E. Atsma, E. J. M. van der Valk
Publikováno v:
Pflugers Archiv
Elevated cardiac troponin-I (cTnI) levels have been demonstrated in serum of patients without acute coronary syndromes, potentially via a stretch-related process. We hypothesize that this cTnI release from viable cardiomyocytes is mediated by stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f736c676e4678241d32b6165da3e39cc
Autor:
H A Davids, L. Hollaar, E. J. M. van der Valk, A. van der Laarse, Wim Th. Hermens, S. A. G. J. Witteveen
Publikováno v:
British heart journal. 41(6)
Serial plasma enzyme determinations were carried out in 32 patients who underwent cardiac surgery with the aid of extracorporeal circulation. Plasma creatine kinase (CK), the cardiospecific isoenzyme of CK (CKMB), and alpha-hydroxybutyrate dehydrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19e17311e8d146618d9a77506c10906
https://pubmed.ncbi.nlm.nih.gov/313803
https://pubmed.ncbi.nlm.nih.gov/313803