Zobrazeno 1 - 10
of 16
pro vyhledávání: '"E. J. Harfenist"'
Autor:
R L, Kinlough-Rathbone, M A, Packham, M A, Guccione, M, Richardson, E J, Harfenist, J F, Mustard
Publikováno v:
Thrombosis and haemostasis. 65(4)
A method has been developed for preparing suspensions of washed human platelets that have lost as much as 90% of their dense granule and alpha granule contents as a result of stimulation by thrombin (0.9 U/ml for 3 min at 37 degrees C), and recoverin
Publikováno v:
Blood. 60:905-911
Because there was a possibility that activated factor XIII (factor XIIIa) might stabilize a platelet-fibrinogen aggregate through its crosslinking action, we have isolated plasma factor XIII, activated it, and studied the effect of factor XIIIa at a
Publikováno v:
Blood. 56:189-198
Publikováno v:
Blood. 64:1163-1168
When platelets are stimulated with adenosine diphosphate (ADP), fibrinogen binds to receptors on the platelet membrane, and the platelets aggregate. The primary platelet recognition sites of human fibrinogen are reported to be at the COOH-terminal en
Publikováno v:
Blood. 70:827-831
To investigate the suggestion that von Willebrand factor (vWf) can substitute for fibrinogen in supporting ADP-induced aggregation of human platelets, we studied platelet reactions in two media: (1) a high calcium medium, Tyrode-albumin solution cont
Publikováno v:
The Journal of laboratory and clinical medicine. 97(5)
125I-fibrinogen binds to washed rabbit platelets when they ar stimulated wit ADP, and it has previously been observed that fibrinogen binding is prevented by several inhibitors of ADP-induced aggregation. We have now shown that other inhibitors of ag
Autor:
M A, Guccione, R L, Kinlough-Rathbone, M A, Packham, E J, Harfenist, M L, Rand, J P, Greenberg, D W, Perry, J F, Mustard
Publikováno v:
Thrombosis and haemostasis. 53(1)
The effects of plasmin have been examined because platelets may be exposed to plasmin in vivo and treatment of platelets with plasmin shortens platelet survival. Rabbit plasmin was prepared by urokinase activation of plasminogen immobilized on lysine
Publikováno v:
Thrombosis and Haemostasis Vth Congress.
A polypeptide with a molecular weight of approximately 20,000 daltons, produced at an early stage in the degradation of human fibrinogen by plasmin, has been isolated. Its amino acid composition is unique in that most of the residues are hydrophilie,
Publikováno v:
Thrombosis and haemostasis. 35(1)
Distinction between fibrinopeptide A (FPA) and larger polypeptides containing the FPA sequence is critical for the interpretation of clinical results with FPA immunoassay methods. Therefore, the immunochemical reactivity of 14 rabbit anti-FPA sera wi
Publikováno v:
Thrombosis and haemostasis. 49(3)
Washed human platelets aggregated by ADP can be deaggregated by EDTA or PGE1, provided the release reaction does not occur; when the release reaction occurs platelets deaggregate less readily. Platelets treated with chymotrypsin are aggregated by fib