Výsledky vyhledávání - "E. J. ALEXANDER"

Serum IGFBP-2 levels are associated with reduced insulin sensitivity in obese children

Autor: S W, Yau, B E, Harcourt, K-T, Kao, E J, Alexander, V C, Russo, G A, Werther, M A, Sabin

Publikováno v: Clinical obesity. 8(3)

Insulin-like growth factor binding protein 2 (IGFBP-2) may represent a critical link between body composition and insulin sensitivity. We investigated the relationship between circulating IGFBP-2 levels, body composition, insulin sensitivity, energy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21ac4b6e764379e0d42fe26b3b3ded62
https://pubmed.ncbi.nlm.nih.gov/29493116

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Aminoalkylindoles: Structure-Activity Relationships of Novel Cannabinoid Mimetics

Autor: Malcolm R. Bell, Eissenstat Ma, E. J. Alexander, Olefirowicz Em, James H. Ackerman, Gruett, Thomas E. D'Ambra, Kumar, Sol J. Daum, Estep Kg

Publikováno v: Journal of Medicinal Chemistry. 38:3094-3105

Aminoalkylindoles (AAIs) are a novel series of cannabinoid receptor ligands. In this report we disclose the structural features of AAIs which are important for binding to this receptor as measured by inhibition of binding of [ 3 H]Win 55212-2 (5). Fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7ed5c57cee63b2a01fc4e34b76e307
https://doi.org/10.1021/jm00016a013

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Akademický článek

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Synthesis and antidepressant properties of novel 2-substituted 4,5-dihydro-1H-imidazole derivatives

Autor: R A Ferrari, E. J. Alexander, Daniel Luttinger, Mark H. Perrone, Dean R. Haubrich, Denis M. Bailey, M. J. Castaldi, Mark P. Wentland

Publikováno v: Journal of Medicinal Chemistry. 30:1482-1489

A unique combination of alpha 2-adrenoreceptor antagonist and serotonin-selective reuptake inhibitory activities has been identified in a series of 2-substituted 4,5-dihydro-1H-imidazole derivatives. This combination of blocking activities has provid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4ef70b38752bd43e5f60a3da88a730
https://doi.org/10.1021/jm00391a034

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Syntheses and complement inhibitory activities of 4-(2-phenyl-1H-indol-3-yl)cyclohexane-1-carboxylic acids

Autor: R. A. Patrick, G. D. Degrazia, R. G. Powles, Denis M. Bailey, M. E. Fairbain, Robert E. Johnson, D. J. Pruden, E. J. Alexander, B. G. Heerdt

Publikováno v: Journal of Medicinal Chemistry. 28:160-164

The syntheses of 4-(2-phenyl-1H-indol-3-yl)cyclohexane-1-carboxylic acids are described. These compounds express potent in vitro inhibition of the human classical complement pathway, and qualitative SAR have been determined. Several of the in vitro a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2bff5ede92e09340a8f63ef7c0fbdd
https://doi.org/10.1021/jm00380a002

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