Výsledky vyhledávání - "E. Imogen Wilding"

Enterococcus faecalis Acetoacetyl-Coenzyme A Thiolase/3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase, a Dual-Function Protein of Isopentenyl Diphosphate Biosynthesis

Autor: Cynthia V. Stauffacher, John W. Burgner, Autumn Sutherlin, Kevin R. Lehnbeuter, E. Imogen Wilding, Victor W. Rodwell, Damien McDevitt, Marie J. Mazzulla, Pamela Lane, Michael N. Gwynn, Matija Hedl

Publikováno v: Bindley Publications

Many bacteria employ the nonmevalonate pathway for synthesis of isopentenyl diphosphate, the monomer unit for isoprenoid biosynthesis. However, gram-positive cocci exclusively use the mevalonate pathway, which is essential for their growth (E. I. Wil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35170e53caf399a86f3f6bf2124d3d0
https://doi.org/10.1128/jb.184.8.2116-2122.2002

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Identification, Evolution, and Essentiality of the Mevalonate Pathway for Isopentenyl Diphosphate Biosynthesis in Gram-Positive Cocci

Autor: E. Imogen Wilding, Serban Iordanescu, Michael N. Gwynn, David J. Holmes, Karen A. Ingraham, Alison F. Chalker, James R. Brown, Chi Y. So, Martin Rosenberg, Alexander P. Bryant

Publikováno v: Journal of Bacteriology. 182:4319-4327

The mevalonate pathway and the glyceraldehyde 3-phosphate (GAP)–pyruvate pathway are alternative routes for the biosynthesis of the central isoprenoid precursor, isopentenyl diphosphate. Genomic analysis revealed that the staphylococci, streptococc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25759c53263559af49a612c74074256
https://doi.org/10.1128/jb.182.15.4319-4327.2000

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Essentiality, Expression, and Characterization of the Class II 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase of Staphylococcus aureus

Autor: Cynthia V. Stauffacher, Damien McDevitt, E. Imogen Wilding, R. Dwayne Lunsford, Joseph E. Myers, Alexander P. Bryant, Michael N. Gwynn, Victor W. Rodwell, Martin Rosenberg, Dong-Yul Kim, Sylvester Daniel R

Sequence comparisons have implied the presence of genes encoding enzymes of the mevalonate pathway for isopentenyl diphosphate biosynthesis in the gram-positive pathogen Staphylococcus aureus . In this study we showed through genetic disruption exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4a563f17568f06d40e27a343734162
https://europepmc.org/articles/PMC94663/

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