Zobrazeno 1 - 10
of 14
pro vyhledávání: '"E. I. Walter"'
Autor:
E I Walter, Hui Kuo G. Shu, Chi Ming Chang, Lakshmeswari Ravi, Hsing Jien Kung, Lei Ling, Chris M. Castellano, Robert J. Pelley
Publikováno v:
Molecular and Cellular Biology. 14:6868-6878
Avian c-erbB is activated to a leukemia oncogene following truncation of its amino-terminal ligand-binding domain by retroviral insertion. The insertionally activated transcripts encode protein products which have constitutive tyrosine kinase activit
Publikováno v:
Journal of Biological Chemistry. 267:1245-1252
The inositol ring in the glycoinositolphospholipid (GPI) anchor of human decay-accelerating factor (DAF) is unmodified in nucleated cells, whereas it is fatty acid acylated in erythrocytes (Ehu). To assess the effect of this and of the glycerol sn-2-
Publikováno v:
The Journal of Immunology. 145:3836-3841
Decay-accelerating factor (DAF) is a C regulatory protein which functions in membranes to inhibit autologous C activation on cell surfaces. A liposome model was used to study the mechanism of DAF action and examine the effects of membrane-bound glyco
Publikováno v:
The Journal of Immunology. 144:1030-1036
Human decay-accelerating factor (DAF) proteins expressed on E and nucleated cells differ in their susceptibility to phosphatidylinositol (PI)-specific phospholipase C (PLC) cleavage/release. To investigate the mechanism of this difference, the glycoi
Publikováno v:
The Journal of biological chemistry. 267(2)
The inositol ring in the glycoinositolphospholipid (GPI) anchor of human decay-accelerating factor (DAF) is unmodified in nucleated cells, whereas it is fatty acid acylated in erythrocytes (Ehu). To assess the effect of this and of the glycerol sn-2-
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(11)
Decay-accelerating factor (DAF) is a C regulatory protein which functions in membranes to inhibit autologous C activation on cell surfaces. A liposome model was used to study the mechanism of DAF action and examine the effects of membrane-bound glyco
Autor:
J H, Lass, E I, Walter, T E, Burris, H E, Grossniklaus, M I, Roat, D L, Skelnik, L, Needham, M, Singer, M E, Medof
Publikováno v:
Investigative ophthalmologyvisual science. 31(6)
Complement is present in ocular fluids, but the molecular mechanism(s) restricting its activation to exogenous targets and not to autologous ocular cells are currently unknown. To clarify how this control is achieved, monoclonal antibody (mAb)-based
Publikováno v:
The Journal of Experimental Medicine
Decay-accelerating factor (DAF) is a 70 kD membrane regulatory protein that prevents the activation of autologous complement on cell surfaces. Using immunohistochemical methods and a radioimmunometric assay based on mAbs to DAF, we found large amount
Publikováno v:
The Journal of Immunology. 141:2924-2928
Recent studies have identified cell-associated proteins that are membrane anchored by glycosyl-inositol-phospholipid structures but the biologic implications of this mode of membrane attachment are incompletely understood. Among proteins anchored in
Autor:
Hui Kuo G. Shu, D J Ayers, E I Walter, Christopher A. Hauer, Robert R. Getty, Richard K. Groger, M E Medof, Mark L. Tykocinski
Publikováno v:
Proceedings of the National Academy of Sciences. 85:3555-3559
Decay-accelerating factor (DAF) is one of a family of cell-associated proteins that undergo posttranslational modifications in which glycolipid anchoring structures are substituted for membrane-spanning sequences. The signals that direct the covalent