Zobrazeno 1 - 5
of 5
pro vyhledávání: '"E. I. Magura"'
Publikováno v:
Neuroscience. 81:345-351
The action of synthetic kava pyrones, (+)-methysticin and (+/-)-kavain, on voltage-operated Na(+)-channels was studied in whole-cell patch-clamped CA1 hippocampal neurons. In doses of 1-400 microM, both compounds exerted a rapid and reversible inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4343c946b67046aa90dff65e6530f81e
https://doi.org/10.1016/s0306-4522(97)00177-2
https://doi.org/10.1016/s0306-4522(97)00177-2
Publikováno v:
Scopus-Elsevier
The effects of a synthetic 5,6-dihydro-alpha-kava-pyrone (+)-methysticin on voltage-operated Na+ channels was studied in isolated whole-cell patch-clampedCA1 hippocampal neurons. Within a concentration range of 1–400 µM, (+)-methysticin induced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b34318c2e011cc1258dfa0183d81fcd
https://doi.org/10.1007/bf02262775
https://doi.org/10.1007/bf02262775
Autor:
E. I. Magura
Publikováno v:
Neurophysiology. 28:173-177
Effects of a kava-pyrone (±)-kavain on fast inactivation of Na+ channels were studied in experiments on isolated neurons from the rat hippocampus. (±)-Kavain was found to block Na+ channels, and its effect was voltage-dependent. At the holding pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ee604a7dddad679fc4554bb971e41a
https://doi.org/10.1007/bf02262780
https://doi.org/10.1007/bf02262780
Publikováno v:
Scopus-Elsevier
The dependence of the efficacy of the influence of a kava-pyrone (±)-kavain (330 µM) on the frequency of activation of Na+ channels and voltage dependence of the effects of (±)-kavain on the rate of inactivation of these channels were studied in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b89695a0cd8b36b993f904c61fee642
http://www.scopus.com/inward/record.url?eid=2-s2.0-27544502601&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-27544502601&partnerID=MN8TOARS
Publikováno v:
Scopus-Elsevier
A study of the effects of (+)-methysticin on sodium channels of isolated neurons from theCA1 hippocampal area of rats showed that this drug considerably accelerabed the inactivation processes providing that the membrane potential was within the −80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cf27722b344a0cbc47c5bcd9c86d01
http://www.scopus.com/inward/record.url?eid=2-s2.0-33750137119&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-33750137119&partnerID=MN8TOARS