Výsledky vyhledávání - "E. I. Kvasyuk"

Molnupiravir as a promising prodrug agent for therapy of COVID-19

Autor: L. L. Birichevskaya, E. I. Kvasyuk, A. I. Zinchenko

Publikováno v: Proceedings of the National Academy of Sciences of Belarus, Biological Series. 67:426-432

The ongoing COVID-19 pandemic accompanied by the emergence of new successive pathogenic variants makes problematic the prospects of the approach based on application of exclusively prophylactic vaccines to combat SARSCoV-2. This reason motivated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86f2b0c073525f2e967877f7cd1d640d
https://doi.org/10.29235/1029-8940-2022-67-4-426-432

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Distribution of fluorescence decay times for 1-anilinonaphthalene-8-sulfonate in human oxyhemoglobin A1b solution

Autor: B. A. Bushuk, O. S. Bokut, V. E. Syakhovich, A. S. Drazdou, E. I. Kvasyuk, A. N. Sobchuk, S. B. Bokut

Publikováno v: Journal of Applied Spectroscopy. 79:437-445

We have studied complex formation between molecules of the fluorescent probe 1-anilinonaphthalene-8-sulfonate (1,8-ANS) and the major form (A1) and a minor form (Ab) of hemoglobin. The contribution of the longlived component f3 to the kinetic curves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7eb8f8c0172945ebff5cba3d437aadc
https://doi.org/10.1007/s10812-012-9620-4

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Nucleotides, Part LXVII, The 2-Cyanoethyl and (2-Cyanoethoxy)carbonyl Group for Base Protection in Nucleoside and Nucleotide Chemistry

Autor: Wolfgang Pfleiderer, Tilman Reiner, E. I. Kvasyuk, Claudia Merk

Publikováno v: Helvetica Chimica Acta. 83:3198-3210

The amino functions of the common 2′-deoxyribo- and ribonucleosides were blocked by the (2-cyanoethoxy)carbonyl group on treatment with 2-cyanoethyl carbonochloridate (5) or 1-[(2-cyanoethoxy)carbonyl]-3-methyl-1H-imidazolium chloride (6) leading t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee854b219faebf21bb6dc639b80eac19
https://doi.org/10.1002/1522-2675(20001220)83:12<3198::aid-hlca3198>3.0.co

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Nucleotides, Part LXVI,β-Heteroarylethyl Groups - New Phosphate-Protecting Groups for Phosphotriester Chemistry

Autor: Wolfgang Pfleiderer, Tilman Reiner, E. I. Kvasyuk

Publikováno v: Helvetica Chimica Acta. 83:3053-3063

The β-heteroaryl-substituted ethanols 6 – 10 were synthesized and, together with pyridine-2-ethanols and pyridine-4-ethanols, were tested as a new type of phosphate-protecting groups in the synthesis of oligonucleotides by the phosphotriester appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff607ef4f0984d6b744b55d745072536
https://doi.org/10.1002/1522-2675(20001108)83:11<3053::aid-hlca3053>3.0.co

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New Photolabile Protecting Groups in Nucleoside and Nucleotide Chemistry—Synthesis, Cleavage Mechanisms and Applications

Autor: Ramamurthy Charubala, Wolfgang Pfleiderer, H. Giegrich, Chr Hermann, S. Eisele-Bühler, E. I. Kvasyuk

Publikováno v: Nucleosides and Nucleotides. 17:1987-1996

New photolabile protecting groups have been found in the 2-(2-nitrophenyl)ethoxycarbonyl and the 2-(2-nitrophenyl)ethylsulfonyl group, respectively. The influence of substituents at the phenyl ring as well as the side-chain has been investigated rega

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b90e24d1600e9aa0ef36932ec7f17fd
https://doi.org/10.1080/07328319808004738

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Chemical-Enzymatic Synthesis of 3′-Amino-2′, 3′-dideoxy-β-D-ribofuranosides of Natural Heterocyclic Bases and Their 5′-Monophosphates

Autor: Vladimir N. Barai, A. I. Zinchenko, E. V. Vaaks, E. I. Kvasyuk, S. B. Bokut, G. V. Zaitseva, Igor A. Mikhailopulo

Publikováno v: Nucleosides and Nucleotides. 13:819-834

Treatment of O2, 3′-anhydro-5′-O-trityl derivatives of thymidine (1) and 2′-deoxyuridine (2) with lithium azide in dimethylformamide at 150 °C resulted in the formation of the corresponding isomeric 3′-azido-2′, 3′-dideoxy-5′-O-trityl-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9622356ada780c2fc775e4621f768bc1
https://doi.org/10.1080/15257779408013281

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ChemInform Abstract: Synthesis and Antiviral and Cytostatic Properties of 3′-Deoxy-3′- fluoro- and 2′-Azido-3′-fluoro-2′,3′-dideoxy-D-ribofuranosides of Natural Heterocyclic Bases

Autor: Igor A. Mikhailopulo, Tamara I. Pricota, E. I. Kvasyuk, Jan Balzarini, Grigorii G. Sivets, Nicolai E. Poopeiko, E. De Clercq

Publikováno v: ChemInform. 22

A series of 3'-deoxy-3'-fluoro- and 2'-azido-2',3'-dideoxy-3'-fluoro-D-ribofuranosides of natural heterocyclic bases have been synthesized with the use of universal carbohydrate precursors, viz., 1-O-acetyl-2,5-di-O-benzoyl-3-deoxy-3-fluoro-D-ribofur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2218de298a52b7b0f21c316f24acd6c5
https://doi.org/10.1002/chin.199152311

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