Renal Handling of Glucagon and Insulin

Autor: Peterson Dr, S. Oparil, E. I. Christensen, J. T. Hjelle, Frank A. Carone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8945ebff3d7ce4f393f2bbb997fa7e81
https://doi.org/10.1159/000409958

Renal albumin absorption in physiology and pathology

Autor: Henrik Birn, E. I. Christensen

Publikováno v: Birn, H & Christensen, E I 2006, ' Renal albumin absorption in physiology and pathology ' Kidney International, vol. 69, pp. 440-449 .

Albumin is the most abundant plasmaprotein serving multiple functions as a carrier of metabolites, hormones, vitamins, and drugs, as an acid/base buffer, as antioxidant and by supporting the oncotic pressure and volume of the blood. The presence of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bcfc3322ef480360f522a8e2292dae

An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

Autor: E. I. Christensen, Henrik Vorum, Duska Dragun, Thomas E. Willnow, Diego J. Walther, Anders Nykjaer, Joachim Herz, Flemming Melsen, Christian Jacobsen

Publikováno v: Nykjaer, A, Dragun, D, Walther, D, Vorum, H, Jacobsen, C, Herz, J, Melsen, F, Christensen, E I & Willnow, T E 1999, ' An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3 ' Gekkan Saibo, bind 96, nr. 4, s. 507-515 .
Nykjaer, A, Dragun, D, Walther, D, Vorum, H, Jacobsen, C, Herz, J, Melsen, F, Christensen, E I & Willnow, T E 1999, ' An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3 ', Cell, vol. 96, no. 4, pp. 507-15 .

Steroid hormones may enter cells by diffusion through the plasma membrane. However, we demonstrate here that some steroid hormones are taken up by receptor-mediated endocytosis of steroid-carrier complexes. We show that 25-(OH) vitamin D3 in complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e0a60c5e757e9f0f7155573f0676f7
https://doi.org/10.1016/s0092-8674(00)80655-8

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

Autor: Søren K. Moestrup, E I Christensen, Timothy G. Hammond, Bellur Seetharam, Pierre J. Verroust

Publikováno v: Scopus-Elsevier

Previous studies in the rat have shown that antibodies to gp280, a protein > 200 kD and closely associated with the early endocytic system can induce fetal malformations. Although gp280 is thought to act as a receptor, its ligand(s) is not known. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6f67009cfcc6326e34b8358afd2028
https://doi.org/10.1172/jci119411

Stepwise degradation of NT in pars convoluta and recta of rabbit proximal tubules: evidence of axial heterogeneity

Autor: E. I. Christensen, Torbjørn Bjerke, M I Sheikh, S. Nielsen

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 264:E45-E53

Reabsorption and degradation of the neuropeptide neurotensin (NT) in rabbit proximal pars convoluta (PC) and pars recta (PR) nephron segments were characterized. Brush-border membrane vesicle fractions (PC or PR) were incubated with [3H]NT, and the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efb6ed859ff527cdb53c2a6d13b2b13
https://doi.org/10.1152/ajpendo.1993.264.1.e45