Zobrazeno 1 - 10
of 66
pro vyhledávání: '"E. Hom"'
Autor:
Anand T.N. Kumar, Eben L. Rosenthal, Mark A. Varvares, Srinivas V. Saladi, Eric Yang, William Faquin, Andrey Prilutskiy, Yu-Jin Lee, Thinzar M. Lwin, Nynke S. van den Berg, Marisa E. Hom, Rahul Pal
Supplementary Figure from First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dca4e04422f3341d24e96768f2a4c4
https://doi.org/10.1158/1078-0432.22486265
https://doi.org/10.1158/1078-0432.22486265
Autor:
Anand T.N. Kumar, Eben L. Rosenthal, Mark A. Varvares, Srinivas V. Saladi, Eric Yang, William Faquin, Andrey Prilutskiy, Yu-Jin Lee, Thinzar M. Lwin, Nynke S. van den Berg, Marisa E. Hom, Rahul Pal
Purpose:Fluorescence molecular imaging, using cancer-targeted near infrared (NIR) fluorescent probes, offers the promise of accurate tumor delineation during surgeries and the detection of cancer specific molecular expression in vivo. However, nonspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020c6bdd5215b3c95dfb9e9045aad1c6
https://doi.org/10.1158/1078-0432.c.6532280.v1
https://doi.org/10.1158/1078-0432.c.6532280.v1
Autor:
Gun Min Youn, Ayden G. Case, Trent Jarin, BaoXiang Li, Aditi Swarup, Andrea Naranjo, Charbel Bou-Khalil, Jacqueline Yao, Quan Zhou, Marisa E. Hom, Eben L. Rosenthal, Albert Y. Wu
Publikováno v:
Translational vision sciencetechnology. 11(7)
Conjunctival squamous cell carcinoma (SCC) is a sight-threatening ocular surface malignancy with the primary treatment modality being surgical resection. To evaluate surgical imaging modalities to improve surgical resection, we established a novel mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6d1502a658c9390858487af0060b9f
https://pubmed.ncbi.nlm.nih.gov/35895055
https://pubmed.ncbi.nlm.nih.gov/35895055
Autor:
Zhiping Feng, Marisa E. Hom, Thomas E. Bearrood, Zachary C. Rosenthal, Daniel Fernández, Alison E. Ondrus, Yuchao Gu, Aaron K. McCormick, Madeline G. Tomaske, Cody R. Marshall, Toni Kline, Che-Hong Chen, Daria Mochly-Rosen, Calvin J. Kuo, James K. Chen
Publikováno v:
Nat Chem Biol
Aldehyde dehydrogenases (ALDHs) are promising cancer drug targets, as certain isoforms are required for the survival of stem-like tumor cells. We have discovered the first selective inhibitors of ALDH1B1, a mitochondrial enzyme that promotes colorect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc28c7f3c7ffb9570bd5f24d18d433b2
https://europepmc.org/articles/PMC9529790/
https://europepmc.org/articles/PMC9529790/
Autor:
Reena Thomas, Wenying Kang, Melanie Hayden Gephart, Eben L. Rosenthal, Johana C. M. Vega Leonel, Guolan Lu, Quan Zhou, Grace Yi, Gordon Li, Marisa E. Hom, Michael, Lawrence Recht, Monica Granucci, Shannon Walters, Hannes Vogel, Gerald A. Grant, Romain Cayrol, Seema Nagpal, Nynke S. van den Berg, Chirag B. Patel, Roan C Raymundo, Naoki Nishio, Yu-Jin Lee, Michael Zhang
Publikováno v:
Theranostics
Rationale: First-line therapy for high-grade gliomas (HGGs) includes maximal safe surgical resection. The extent of resection predicts overall survival, but current neuroimaging approaches lack tumor specificity. The epidermal growth factor receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3425f6ee1b690b6fa3b96a4768d47f
https://doi.org/10.7150/thno.60582
https://doi.org/10.7150/thno.60582
Autor:
Rahul Pal, Marisa E. Hom, Nynke S. van den Berg, Thinzar M. Lwin, Yu-Jin Lee, Andrey Prilutskiy, William Faquin, Eric Yang, Srinivas V. Saladi, Mark A. Varvares, Eben L. Rosenthal, Anand T.N. Kumar
Publikováno v:
Clin Cancer Res
Purpose: Fluorescence molecular imaging, using cancer-targeted near infrared (NIR) fluorescent probes, offers the promise of accurate tumor delineation during surgeries and the detection of cancer specific molecular expression in vivo. However, nonsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5739271104bbe48ad68a752a29bd91
https://europepmc.org/articles/PMC9167767/
https://europepmc.org/articles/PMC9167767/
Autor:
Melanie Hayden Gephart, Roan C Raymundo, Glenn Shields, Hannes Vogel, Monica Granucci, Nynke S. van den Berg, Marisa E. Hom, Eben L. Rosenthal, Wenying Kang, Gordon Li, Mark Roesner, Quan Zhou, Brock A. Martin, Grace Yi, Johana C. M. Vega Leonel, Natalie S. Lui, Stan van Keulen, Jacqueline Pei, Gerald A. Grant, Zachary P Hart, Naoki Nishio, Romain Cayrol, Myrthe Adriana Engelen, Yu-Jin Lee
BackgroundAs receptor-ligand based strategies emerge for surgical imaging, the relative importance of receptor expression in different tumor types is unknown. Near-infrared (NIR) labeled epidermal growth factor receptor (EGFR) antibody, panitumumab-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93117c917a9d24453feeb4c16006c9bd
https://doi.org/10.1101/2021.10.15.21265068
https://doi.org/10.1101/2021.10.15.21265068
Autor:
Ryan K. Orosco, Marisa E. Hom, Quyen T. Nguyen, Fernanda V Pacheco, Yu-Jin Lee, Eben L. Rosenthal, Kayva L Crawford
Publikováno v:
The LaryngoscopeBIBLIOGRAPHY. 132(1)
Objective Fluorescence-guided surgery (FGS) is a rapidly developing intraoperative technology, and many contrast agents are currently under investigation. We sought to provide a review of the current state of FGS clinical trials in Otolaryngology, em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c758048765490444d5da4f1d51fc6401
https://pubmed.ncbi.nlm.nih.gov/34633092
https://pubmed.ncbi.nlm.nih.gov/34633092
Autor:
Marisa E. Hom, Eben L. Rosenthal
Publikováno v:
JAMA Otolaryngol Head Neck Surg
This proof-of-principle clinical trial examines use of intraoperative molecular imaging for localizing visually occult parathyroid glands in both anatomic and ectopic locations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614ad211bb35cba9320edf93846b9c79
https://pubmed.ncbi.nlm.nih.gov/33956088
https://pubmed.ncbi.nlm.nih.gov/33956088
Publikováno v:
ChemMedChem
Gli transcription factors within the Hedgehog (Hh) signaling pathway direct key events in mammalian development and promote a number of human cancers. Current therapies for Gli-driven tumors target Smoothened (SMO), a G protein-coupled receptor-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2c7d600154f819a2f15736942790e2
https://europepmc.org/articles/PMC7311267/
https://europepmc.org/articles/PMC7311267/