Zobrazeno 1 - 10 of 117 pro vyhledávání: '"E. Hodgkin"'
2
Outcomes From a Patient-Centered Residential Treatment Plan for Tobacco Dependence
Autor: David P.L. Sachs, Janet Brigham, Bonnie L. Sachs, Susan J.S. Waldron, Gary E. Swan, Betsy L. Titus, Lisa M. Jack, John E. Hodgkin
Publikováno v: Mayo Clinic Proceedings. 88:970-976
St. Helena Hospital launched the first US residential stop-smoking program, The St. Helena Center for a Smoke-Free Life, in 1969. This observational report describes the center's treatment outcome rate for using a patient-centered approach to the use
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5bf9ea99d652e8c426de2f1805ae53
https://doi.org/10.1016/j.mayocp.2013.05.027
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3
Prediction of bond length variation in classical β-lactam structures and enzymatic ring instability
Autor: R. H. Davies, R. P. Sidebotham, E. E. Hodgkin, C. M. Warwick, Martin J. Scanlan, Ian H. Hillier
Publikováno v: International Journal of Quantum Chemistry. 24:231-249
Comparison of intrinsic, solvational, and enzymatic rates of β-lactam ring opening allows rate enhancement due to specific enzyme interactions with given β-lactam moieties to be identified and modeled. Enzymatic rates of β-lactam ring opening may
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::575fedeac07981903f28eee636d36940
https://doi.org/10.1002/qua.560240724
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4
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin
Autor: D. R. Ferry, J. E. Cook, D. Anderson, E. Hodgkin, Leonard W. Seymour, Syed A. Hussain, David J. Kerr, Annie M. Young, Paul Mulholland
Publikováno v: Annals of Oncology. 12:245-248
Summary Background: Quercetin is a naturally occurring flavonoid with many biological activities including inhibition of a number of tyrosine kinases. A phase I, dose-escalati on trial of quercetin defined the maximum tolerated dose (MTD) as 1700 mg/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a7fa11077d6516e1a6a22b500a21ea
https://doi.org/10.1023/a:1008372017097
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6
A Monte Carlo pharmacophore generation procedure: Application to the human PAF receptor
Autor: Edward E. Hodgkin, Mark Whittaker, Andrew Miller
Publikováno v: Journal of Computer-Aided Molecular Design. 7:515-534
A novel pharmacophore definition procedure is described, which uses a Monte Carlo method to superimpose molecules. Pharmacophore space is searched by a technique similar to high temperature annealing. Subsequent refinement of candidate pharmacophores
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8756dd19c985d0983ff470eafff45cbc
https://doi.org/10.1007/bf00124360
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8
Similarity screening of molecular data sets
Autor: Edward E. Hodgkin, A. C. Good, W. G. Richards
Publikováno v: Journal of Computer-Aided Molecular Design. 6:513-520
Three-dimensional (3D)-database searches are now being widely applied to determine potential new active molecules. Many structural data sets obtained as a result of these searches are still large in size. In this paper we apply molecular similarity c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e3ae688085186b0f6f23733bd275ec
https://doi.org/10.1007/bf00130401
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