Zobrazeno 1 - 10
of 446
pro vyhledávání: '"E. Hackett"'
Autor:
Cian J.H. Horneck Johnston, Anna E. Ledwith, Mimmi L.E. Lundahl, Hugo Charles-Messance, Emer E. Hackett, Simon D. O’Shaughnessy, Jonah Clegg, Hannah Prendeville, John P. McGrath, Aaron M. Walsh, Sarah Case, Hollie Austen Byrne, Parth Gautam, Elaine Dempsey, Sinead C. Corr, Frederick J. Sheedy
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109030- (2024)
Summary: Fungal β-glucans are major drivers of trained immunity which increases long-term protection against secondary infections. Heterogeneity in β-glucan source, structure, and solubility alters interaction with the phagocytic receptor Dectin-1
Externí odkaz:
https://doaj.org/article/a82f686f0bfb42e89b2067f61614d09d
Autor:
Sarah Case, Tara O'Brien, Anna E. Ledwith, Shilong Chen, Cian J. H. Horneck Johnston, Emer E. Hackett, Michele O'Sullivan, Hugo Charles-Messance, Elaine Dempsey, Supriya Yadav, Jude Wilson, Sinead C. Corr, Shipra Nagar, Frederick J. Sheedy
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionMacrofungi, such as edible mushrooms, have been used as a valuable medical resource for millennia as a result of their antibacterial and immuno-modulatory components. Mushrooms contain dietary fibers known as β-glucans, a class of polysa
Externí odkaz:
https://doaj.org/article/37c87c6ed6af4e67bcb9f284c3e610a4
Publikováno v:
Atmosphere, Vol 15, Iss 6, p 718 (2024)
This study utilizes in situ measurements and numerical weather prediction forecasts curated during the Coupled Air–Sea Processes Electromagnetic Ducting Research (CASPER) east field campaign to assess how thermodynamic properties in the marine atmo
Externí odkaz:
https://doaj.org/article/d27bba2b188b47f4a7eec99ee1b38e15
Autor:
Clive Drakeford, Sonia Aguila, Fiona Roche, Karsten Hokamp, Judicael Fazavana, Mariana P. Cervantes, Annie M. Curtis, Heike C. Hawerkamp, Sukhraj Pal Singh Dhami, Hugo Charles-Messance, Emer E. Hackett, Alain Chion, Soracha Ward, Azaz Ahmad, Ingmar Schoen, Eamon Breen, Joe Keane, Ross Murphy, Roger J. S. Preston, Jamie M. O’Sullivan, Frederick J. Sheedy, Padraic Fallon, James S. O’Donnell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
von Willebrand factor (VWF) plays a critical role in primary hemostasis following vascular injury by tethering platelets to exposed collagen. Here, VWF binding to macrophages is shown to trigger NF-κB activation and induce pro-inflammatory responses
Externí odkaz:
https://doaj.org/article/0abf998c232d43bcab767dde021ae471
Autor:
Laura E. D’Acunto, Leonard Pearlstine, Saira M. Haider, Caitlin E. Hackett, Dilip Shinde, Stephanie S. Romañach
Publikováno v:
Frontiers in Ecology and Evolution, Vol 11 (2023)
Understanding of the Everglades’ ecological vulnerabilities and restoration needs has advanced over the past decade but has not been applied in an integrated manner. To address this need, we developed the Everglades Vulnerability Analysis (EVA), a
Externí odkaz:
https://doaj.org/article/b5d005f4636846dbaf45dfb43e398ac4
Publikováno v:
Atmosphere, Vol 14, Iss 7, p 1085 (2023)
Direct measurements of profiles of atmospheric properties near the ocean surface and within the marine atmospheric surface layer often contain a large degree of variability. The variability observed can be explained by numerous technical and natural
Externí odkaz:
https://doaj.org/article/34154d76dbf04cee8462fafb40a3bdf4
Publikováno v:
Sensors, Vol 23, Iss 8, p 4099 (2023)
Large knowledge gaps concerning the effect of ocean surface waves on near-surface vertical distributions of temperature and humidity exist due to practical limitations and sensor fidelity challenges of direct measurements. Measurements of temperature
Externí odkaz:
https://doaj.org/article/24d74ed3c4ac44c5a6a46719e5f4b7e2
Publikováno v:
Ecological Indicators, Vol 133, Iss , Pp 108406- (2021)
Indicator species are species which can be monitored as an index to measure the overall health of an ecosystem. Crocodylians have been shown to be good indicators of wetland condition as they respond to changes in hydrology, can be efficiently monito
Externí odkaz:
https://doaj.org/article/8404840498e742f5917dbc3d24298bef
Publikováno v:
Royal Society Open Science, Vol 8, Iss 7 (2021)
Rotor blades can be found in many engineering applications, mainly associated with converting energy from fluids to work (or electricity). Rotor blade geometry is a key factor in the mechanical efficiency of the energy conversion process. For example
Externí odkaz:
https://doaj.org/article/999f488cb0e64c5b8b95528994cbb06a
Autor:
Emer E. Hackett, Frederick J. Sheedy
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The cells of the immune system are reliant on their metabolic state to launch effective responses to combat mycobacterial infections. The bioenergetic profile of the cell determines the molecular fuels and metabolites available to the host, as well a
Externí odkaz:
https://doaj.org/article/8439fcc87fac4791b14e0cde1bfc4f33