Zobrazeno 1 - 10 of 12 pro vyhledávání: '"E. H. SCHACHT"'
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Polymeric prodrugs of mitomycin C designed for tumour tropism and sustained activation
Autor: L W, Seymour, H, Soyez, A, De Marre, M A, Shoaibi, E H, Schacht
Publikováno v: Anti-cancer drug design. 11(5)
Prodrugs of mitomycin C (MMC) based on soluble poly-[N-(2-hydroxyethyl)-L-glutamine] (pHEG) polymers have been evaluated as tumour-targeted drugs. These materials are designed to exploit the enhanced permeability of tumour vasculature, combining a pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::358c0d5e48af7f1b8b4ef05d99c489a1
https://pubmed.ncbi.nlm.nih.gov/8765529
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4
Biodegradable polymers. II. Degradation characteristics of hydrolysis-sensitive poly[(organo)phosphazenes]
Autor: J H, Crommen, E H, Schacht, E H, Mense
Publikováno v: Biomaterials. 13(9)
Polyphosphazenes with hydrolytic labile substituents have potential as biodegradable materials. By proper choice of the substituents, polymers can be prepared which can degrade to harmless products. The rate of biodegradation and the nature of the de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03b82df41f9785118119c524c7e3a6cf
https://pubmed.ncbi.nlm.nih.gov/1391407
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5
Phosphonylation of purified human, canine and porcine cholinesterase by soman. Stereoselective aspects
Autor: H C, De Bisschop, K W, Michiels, L B, Vlaminck, S O, Vansteenkiste, E H, Schacht
Publikováno v: Biochemical pharmacology. 41(6-7)
Cholinesterases (EC 3.1.1.8, acylcholine acylhydrolase) from the sera of man, dog and pig were purified 400-600-fold using a combination of ion-exchange and affinity chromatography. In a first approach, phosphonylation by soman was studied by using t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb4974b62ab1375b088e3a53835a3189
https://pubmed.ncbi.nlm.nih.gov/2009086
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7
Using biodegradable polymers in advanced drug delivery systems
Autor: E H, Schacht
Publikováno v: Medical device technology. 1(1)
Research currently is under way to design novel drug delivery systems that enhance the duration of activity and that provide site-specific release of the drug. Biodegradable polymers represent an important class of materials used in the manufacture o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7de29477d7c1568073239727f3906170
https://pubmed.ncbi.nlm.nih.gov/10148171
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