Výsledky vyhledávání - "E. H. M. Hulsman"

A minimal region on the integrin beta4 subunit that is critical to its localization in hemidesmosomes regulates the distribution of HD1/plectin in COS-7 cells

Autor: C. M. Niessen, Ingrid Kuikman, Arnoud Sonnenberg, L. C. J. M. Oomen, E. H. M. Hulsman

Publikováno v: Europe PubMed Central

The integrin alpha6 beta4 is a major component of hemidesmosomes, in which it mediates firm adhesion to laminin 5. Previous studies have shown that the incorporation of alpha6 beta4 into hemidesmosomes requires a 303 amino acid stretch of the cytopla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e49fc628ec761fa5dc0234de302fa4a
https://doi.org/10.1242/jcs.110.15.1705

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Integrin alpha 6 beta 4 forms a complex with the cytoskeletal protein HD1 and induces its redistribution in transfected COS-7 cells

Autor: P. Sanchez-Aparicio, Arnoud Sonnenberg, C. M. Niessen, E. S. Rots, E. H. M. Hulsman

Publikováno v: Molecular Biology of the Cell. 8:555-566

The integrin alpha 6 beta 4 is a major component of hemidesmosomes, in which it is linked to intermediate filaments. Its presence in these structures is dependent on the beta 4 cytoplasmic domain but it is not known whether beta 4 interacts directly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1075f9bad65a3f3af50f2c5b16ae6f
https://doi.org/10.1091/mbc.8.4.555

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The α6β4 Integrin Is a Receptor for both Laminin and Kalinin

Autor: C. M. Niessen, Lies H. Jaspars, Frans B. L. Hogervorst, A. Sonnenberg, Ingrid Kuikman, E. H. M. Hulsman, G. O. Delwel, A. A. De Melker

Publikováno v: Experimental Cell Research. 211:360-367

Previously, we have establish K562 transfectants that express either alpha 6A beta 1 or alpha 6B beta 1 (K alpha 6A or K alpha 6B) on their surface. Both cell lines bind to laminin and kalinin after treatment with the beta 1-stimulatory antibody TS2/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9363fa4e5b251ede6444fa730a8f050
https://doi.org/10.1006/excr.1994.1099

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Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties

Autor: L. M. H. Van Der Raaij-Helmer, M. F. Jonkman, C. M. Niessen, Arnoud Sonnenberg, R. van der Neut, E. H. M. Hulsman

Publikováno v: Europe PubMed Central

Junctional epidermolysis bullosa (JEB) comprises a group of inherited autosomal recessive blistering disorders characterized by dermo-epidermal separation through the lamina lucida of the basement membrane. We identified a patient with JEB associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175278516765a640e5688363afa6db41
http://europepmc.org/abstract/med/8832392

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