Zobrazeno 1 - 10
of 44
pro vyhledávání: '"E. H. Lebetkin"'
Publikováno v:
Xenobiotica. 36:515-534
The metabolism and disposition of 14C-labelled 2,2',4,4',5-pentabromodiphenyl ether (BDE99) were studied in F344 rats and B6C3F1 mice. Approximately 85% of a 1 micromol kg-1 oral dose was absorbed by male rats and mice. Within 24 h following oral dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e162f16f01751ac8b815dacd91576fa5
https://doi.org/10.1080/00498250600674477
https://doi.org/10.1080/00498250600674477
Publikováno v:
Drug Metabolism and Disposition. 31:892-899
Pulegone is a monoterpene ketone that is usually associated with the herb pennyroyal but is also found in the essential oils from many other mint species. It is the major constituent of pennyroyal oil. Pennyroyal is used as a flavoring and fragrance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8c0d4bd073b45b39d8c1d5cc89cb87
https://doi.org/10.1124/dmd.31.7.892
https://doi.org/10.1124/dmd.31.7.892
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 35(12)
The disposition of [ 14 C]-labeled n -butyl glycidyl ether (BGE, 3-butoxy-1,2-epoxypropane) was studied in rats and mice. The majority of a single p.o. dose (2–200 mg/kg) was excreted in urine (rats, 84–92%; mice, 64–73%) within 24 h. The rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60edde280efdbd7ca3cb41cb5e2f6b81
https://pubmed.ncbi.nlm.nih.gov/17875671
https://pubmed.ncbi.nlm.nih.gov/17875671
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 36(9)
The disposition of the 14C-labelled polybrominated diphenyl ether (PBDE) 2,2',4,4',5,5'-hexaBDE (BDE153) was investigated in rodents following single and multiple doses and in a mixture with radiolabelled 2,2',4,4'-tetraBDE (BDE47) and 2,2',4,4',5-pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f433dd2439025cd6df109e0903fcd67
https://pubmed.ncbi.nlm.nih.gov/16971346
https://pubmed.ncbi.nlm.nih.gov/16971346
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 35(10-11)
The metabolism and disposition of 14C-labelled juglone in male F344 rats following oral, intravenous and dermal administration were studied. Approximately 40-50% of an oral dose (0.1 to 10 mg kg-1) and less than 20% of the dermal dose (4 mg kg-1) wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a273a90a8753b25875f139ed4d461e53
https://pubmed.ncbi.nlm.nih.gov/16393859
https://pubmed.ncbi.nlm.nih.gov/16393859
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 31(10)
(R)-(+)-Menthofuran is a metabolite of (R)-(+)-pulegone, the chief constituent of pennyroyal oil. Menthofuran has been shown to account for a significant percentage of pulegone toxicity through further metabolism to a reactive intermediate, an enonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235414ba146b5fe01cb531a859a51791
https://pubmed.ncbi.nlm.nih.gov/12975329
https://pubmed.ncbi.nlm.nih.gov/12975329
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(12)
(R)-(+)-Pulegone, a monoterpene ketone, is a major component of pennyroyal oil. Ingestion of high doses of pennyroyal oil has caused severe toxicity and occasionally death. Studies have shown that metabolites of pulegone were responsible for the toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d631531a7138ea1e10d867b348774573
https://pubmed.ncbi.nlm.nih.gov/11717176
https://pubmed.ncbi.nlm.nih.gov/11717176
Publikováno v:
Laboratory animal science. 39(1)
Hardwood dust can cause dermatitis, respiratory disease, allergies and nasal cancer in humans. A major concern with animal hardwood bedding is its dust content and its possible effects on animals and animal technicians. Previous reports on the qualit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69b88ddb48c9c4e62a19912de0258d3e
https://pubmed.ncbi.nlm.nih.gov/2918687
https://pubmed.ncbi.nlm.nih.gov/2918687
Publikováno v:
Developmental psychobiology. 15(2)
Pregnant guinea pigs were exposed to loom room noise at 115 dB A for 7.5 hr/day for various periods during the last one-third of pregnancy. When the hearing of their offspring was tested by auditory brain stem-evoked response techniques at 6-dB inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88217d46875fbdf19463e1b8da74f990
https://pubmed.ncbi.nlm.nih.gov/7095284
https://pubmed.ncbi.nlm.nih.gov/7095284
Publikováno v:
Laboratory animal science. 37(5)
A major source of exogenous estrogenic substances, which may affect laboratory animals, comes from the diet. To test the possibility that commercially available rodent diets may significantly influence uterine weights and uterine:body weight (U:BW) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::721a5cdeefa44914c0864a691637fbb2
https://pubmed.ncbi.nlm.nih.gov/3695394
https://pubmed.ncbi.nlm.nih.gov/3695394