Výsledky vyhledávání - "E. H. Holmes"

Measurement of prostate-specific membrane antigen in the serum with a new antibody

Autor: G.M. Kenny, Alton L. Boynton, Benjamin A. Tjoa, S. L. Misrock, V.A. Bowes, Robert J. Barren, Haakon Ragde, Gerald P. Murphy, William T. Tino, S. J. Erickson, E H Holmes

Publikováno v: The Prostate. 28:266-271

Work to date has identified prostate-specific membrane antigen (PSMA) as a membrane-bound glycoprotein with high specificity for prostatic epithelial cells. PSMA reacts with the monoclonal antibody 7E11.C5, which is present in serum, seminal fluid, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8ad62a7d3077904bfd783c8d40f2ab3
https://doi.org/10.1002/(sici)1097-0045(199604)28:4<266::aid-pros7>3.0.co

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Structure-Function Analysis of Human α1→3Fucosyltransferases

Autor: E H Holmes, Zhenghai Xu, Anne L. Sherwood, Bruce A. Macher

Publikováno v: Journal of Biological Chemistry. 270:8145-8151

Human alpha 1-->3fucosyltransferases constitute a family of closely related membrane-bound enzymes distinguished by differences in acceptor specificities and inherent protein biochemical properties. One such biochemical property is sensitivity to enz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ed3c912f43b674f70e685589fc39539
https://doi.org/10.1074/jbc.270.14.8145

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Western blot assay for prostate-specific membrane antigen in serum of prostate cancer patients

Autor: Julius S. Horoszewicz, Alton L. Boynton, Gerald M. Kenny, Yvan P. Rochon, Robert J. Barren, Gerald P. Murphy, S. J. Erickson, E H Holmes

Publikováno v: The Prostate. 25:219-223

There is a need for the development of new diagnostic tools for the early detection of prostate cancer. A candidate molecule for a new screening test is a prostate-specific membrane antigen (PSM) recognized by the monoclonal antibody 7E11.C5. We carr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2744bd866d794e7b8f74f2d67f4a39
https://doi.org/10.1002/pros.2990250408

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Photoidentification of mannosyltransferases of dolichol cycle in the mammary gland. Purification and characterization of GDP-Man:Man beta 1–>4GlcNAc beta 1–>4GlcNAc-P-P-dolichol mannosyltransferase

Autor: Ashok Mudgapalli, E. H. Holmes, S. K. Roy, Inder K. Vijay

Publikováno v: Journal of Biological Chemistry. 269:11327-11336

Glc3Man9GlcNAc2-P-P-Dol serves as the major precursor for the biosynthesis of asparagine-linked glycoproteins in eukaryotes. The first 5 of the 9 mannosyl residues during the assembly of the oligosaccharide moiety within the dolichol cycle in the end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ea4bb1e2bad4a186254e764eaf4aa40
https://doi.org/10.1016/s0021-9258(19)78129-0

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De Novo Synthesis of Type 1 Lacto-Series Glycolipids in Human Colonic Adenocarcinoma Cells: Efficient Synthesis of the Lea Antigen and Absence of Brefeldin A-Induced Inhibition of Its Synthesis in Colo 205 Cells

Autor: E H Holmes, Thomas G. Greene

Publikováno v: Archives of Biochemistry and Biophysics. 305:328-340

De novo biosynthesis of lacto-series type 1 chain glycolipids was studied by [ 3 H]serine metabolic labeling of ceramide in Colo 205 and SW403 cells. Highly efficient synthesis of III 4 FucLc 4 (Le a ) from lactosylceramide was found to be characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76a66eba4163e4c8ff6833cd338f3d0
https://doi.org/10.1006/abbi.1993.1430

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Brefeldin A induced inhibition of de novo globo- and neolacto-series glycolipid core chain biosynthesis in human cells. Evidence for an effect on beta 1–>4galactosyltransferase activity

Autor: E H Holmes, Anne L. Sherwood

Publikováno v: Journal of Biological Chemistry. 267:25328-25336

De novo synthesis of neolacto-series glycolipids has been studied in human cell lines via metabolic labeling of ceramide with [3H]serine. Intense labeling of ceramide mono- and dihexoside glycolipids occurred with labeling of progressively longer cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b290a2bbb1f48a980b43941389b13f41
https://doi.org/10.1016/s0021-9258(19)74044-7

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Preclinical evaluation of a monoclonal antibody (3C6) specific for prostate-specific membrane antigen

Autor: K. Garmestani, D. E. Milenic, M. W. Brechbiel, Celeste A. S. Regino, P. L. Choyke, Karen J. Wong, E. H. Holmes

Better tumor markers are needed for early diagnosis and staging of prostate cancer, and for monitoring therapeutic response than the currently used prostate specific antigen (PSA). Prostate specific membrane antigen (PSMA) is highly expressed on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cacbab70aa3bc35dfcbb35a91805e9
https://europepmc.org/articles/PMC2678849/

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Photoaffinity labeling of GDP-fucose:nLcOse4Cer alpha 1----3-fucosyltransferase from human small cell lung carcinoma NCI-H69 cells with the GDP-fucose analog GDP-hexanolaminyl-4-azidosalicylic acid

Autor: E H Holmes

Publikováno v: Journal of Biological Chemistry. 265:13150-13156

An iodinatable photoactive analog of GDP-fucose, GDP-hexanolaminyl-4-azidosalicylic acid, has been prepared and applied to studies of the previously described alpha 1----3-fucosyltransferase from NCI-H69 cells (Holmes, E. H., Ostrander, G. K., and Ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bddb881bc7dfa7eeee4e0347bea8a514
https://doi.org/10.1016/s0021-9258(19)38279-1

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Prostate-specific antigen levels in young white and black men 20 to 45 years old

Autor: Gerald P. Murphy, Judd W. Moul, Debra J. Jacobson, Mark V. Rubertone, Steven J. Jacobsen, E H Holmes, David M. Preston, Lynn I. Levin

Publikováno v: Urology. 56(5)

Objectives. To determine the prostate-specific antigen (PSA) levels and PSA change over time in young white and black men 20 to 45 years old. Methods. The Department of Defense Serum Repository, a serum bank that stores all residual serum from the mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316ddb813e2ed6490d0e5cdd754a8c64
https://pubmed.ncbi.nlm.nih.gov/11068308

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